Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6FZ_RS06115 Genome accession   NZ_CP172361
Coordinates   1176857..1178659 (-) Length   600 a.a.
NCBI ID   WP_002853165.1    Uniprot ID   -
Organism   Campylobacter jejuni strain YH023     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1171857..1183659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FZ_RS06090 (ACH6FZ_06090) - 1171982..1173181 (+) 1200 WP_002853238.1 MFS transporter -
  ACH6FZ_RS06095 (ACH6FZ_06095) ciaC 1173237..1173557 (+) 321 WP_002853224.1 invasion antigen CiaC -
  ACH6FZ_RS06100 (ACH6FZ_06100) hemE 1173741..1174763 (+) 1023 WP_002853233.1 uroporphyrinogen decarboxylase -
  ACH6FZ_RS06105 (ACH6FZ_06105) - 1174760..1175662 (+) 903 WP_002853222.1 radical SAM protein -
  ACH6FZ_RS06110 (ACH6FZ_06110) - 1175659..1176855 (-) 1197 WP_002853187.1 hypothetical protein -
  ACH6FZ_RS06115 (ACH6FZ_06115) uvrC 1176857..1178659 (-) 1803 WP_002853165.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6FZ_RS06120 (ACH6FZ_06120) - 1178652..1179146 (-) 495 WP_002859309.1 hypothetical protein -
  ACH6FZ_RS06125 (ACH6FZ_06125) guaA 1179285..1180820 (+) 1536 WP_002853189.1 glutamine-hydrolyzing GMP synthase -
  ACH6FZ_RS06130 (ACH6FZ_06130) - 1180906..1182366 (+) 1461 WP_002853236.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69665.69 Da        Isoelectric Point: 9.4464

>NTDB_id=952356 ACH6FZ_RS06115 WP_002853165.1 1176857..1178659(-) (uvrC) [Campylobacter jejuni strain YH023]
MTKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVRSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKLISREKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVMQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=952356 ACH6FZ_RS06115 WP_002853165.1 1176857..1178659(-) (uvrC) [Campylobacter jejuni strain YH023]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTTAGATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACTCATCAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTAAAAATTCCGTGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATCGTAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATTAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATGCAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.079

97

0.457