Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6FS_RS06235 Genome accession   NZ_CP172358
Coordinates   1199130..1200932 (-) Length   600 a.a.
NCBI ID   WP_395766042.1    Uniprot ID   -
Organism   Campylobacter jejuni strain YH024     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1194130..1205932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FS_RS06210 (ACH6FS_06210) - 1194259..1195458 (+) 1200 WP_004314672.1 MFS transporter -
  ACH6FS_RS06215 (ACH6FS_06215) ciaC 1195514..1195834 (+) 321 WP_002876791.1 invasion antigen CiaC -
  ACH6FS_RS06220 (ACH6FS_06220) hemE 1196014..1197036 (+) 1023 WP_004314676.1 uroporphyrinogen decarboxylase -
  ACH6FS_RS06225 (ACH6FS_06225) - 1197033..1197935 (+) 903 WP_004314678.1 radical SAM protein -
  ACH6FS_RS06230 (ACH6FS_06230) - 1197932..1199128 (-) 1197 WP_002882189.1 hypothetical protein -
  ACH6FS_RS06235 (ACH6FS_06235) uvrC 1199130..1200932 (-) 1803 WP_395766042.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6FS_RS06240 (ACH6FS_06240) - 1200925..1201419 (-) 495 WP_002859309.1 hypothetical protein -
  ACH6FS_RS06245 (ACH6FS_06245) guaA 1201558..1203093 (+) 1536 WP_002853189.1 glutamine-hydrolyzing GMP synthase -
  ACH6FS_RS06250 (ACH6FS_06250) - 1203179..1204639 (+) 1461 WP_002853236.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69647.65 Da        Isoelectric Point: 9.4464

>NTDB_id=952309 ACH6FS_RS06235 WP_395766042.1 1199130..1200932(-) (uvrC) [Campylobacter jejuni strain YH024]
MTKENLENELKTLPNSTGVYQYFNQEGKLLYVGKAKNLKNRVRSYFAFTPNLHANPRNSLRIQKMIEETVHLEFIATNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKLISREKYLEILDEAIHALLNPSVLLKNLEKQMLVLAQNENYEEAAKVRDQIAMIKDLEV
KVEIDIAKLEDFEVFALAFKNSVLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVIQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=952309 ACH6FS_RS06235 WP_395766042.1 1199130..1200932(-) (uvrC) [Campylobacter jejuni strain YH024]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTACTGGCGTTTATCAATACTTCAATCAAGAAGG
AAAGCTTTTATATGTAGGCAAGGCTAAAAATCTTAAAAATCGTGTTAGATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATTGCTACTAATTCAGAG
GCTGATGCTTTGATTTTAGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACTCATCAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATACACGCACTTTTAAATCCTAGTGTTTTGCTTAAAAACTTAGAAAAACAAATGC
TTGTTTTAGCACAAAATGAAAATTACGAAGAAGCAGCTAAAGTAAGAGATCAGATTGCAATGATTAAAGATTTGGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTAAAAATTCCGTGCTTTCAACCTT
GCGTTTTGTGGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATCGTAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

47.079

97

0.457