Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   AAA985_RS02870 Genome accession   NZ_AP028603
Coordinates   536133..536864 (+) Length   243 a.a.
NCBI ID   WP_000889919.1    Uniprot ID   Q8DQW7
Organism   Streptococcus pneumoniae strain Pne2     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 531133..541864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA985_RS02845 (TKY181970_05570) dnaK 531317..533140 (+) 1824 WP_000034662.1 molecular chaperone DnaK -
  AAA985_RS02850 (TKY181970_05580) - 533142..533498 (+) 357 WP_000114422.1 hypothetical protein -
  AAA985_RS02855 (TKY181970_05590) dnaJ 533900..535036 (+) 1137 WP_001066301.1 molecular chaperone DnaJ -
  AAA985_RS02860 (TKY181970_05600) - 535358..535645 (-) 288 WP_000777760.1 hypothetical protein -
  AAA985_RS02865 (TKY181970_05610) - 535655..536065 (-) 411 WP_001278301.1 HIT family protein -
  AAA985_RS02870 (TKY181970_05620) pptA 536133..536864 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  AAA985_RS02875 (TKY181970_05630) pptB 536861..537910 (+) 1050 WP_000653773.1 ABC transporter permease Regulator
  AAA985_RS02880 (TKY181970_05640) - 538078..538407 (-) 330 WP_000132572.1 hypothetical protein -
  AAA985_RS02885 (TKY181970_05650) - 538683..539021 (+) 339 WP_000682126.1 LytTR family DNA-binding domain-containing protein -
  AAA985_RS02890 (TKY181970_05660) comE/blpR 539026..539763 (+) 738 WP_001219143.1 response regulator transcription factor Regulator
  AAA985_RS02895 (TKY181970_05670) - 539777..541117 (+) 1341 WP_001028651.1 sensor histidine kinase -
  AAA985_RS02900 (TKY181970_05680) blpC 541162..541317 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27012.49 Da        Isoelectric Point: 4.7737

>NTDB_id=95214 AAA985_RS02870 WP_000889919.1 536133..536864(+) (pptA) [Streptococcus pneumoniae strain Pne2]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=95214 AAA985_RS02870 WP_000889919.1 536133..536864(+) (pptA) [Streptococcus pneumoniae strain Pne2]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTAGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACAAAAGAG
GAGGACCTATGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DQW7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.614

99.177

0.72
  pptA Streptococcus thermophilus LMD-9

71.784

99.177

0.712

Multiple sequence alignment