Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACH6FO_RS06380 Genome accession   NZ_CP172351
Coordinates   1222986..1224788 (-) Length   600 a.a.
NCBI ID   WP_038817224.1    Uniprot ID   -
Organism   Campylobacter jejuni strain YH028     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1217986..1229788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH6FO_RS06355 (ACH6FO_06355) - 1218115..1219314 (+) 1200 WP_038817225.1 MFS transporter -
  ACH6FO_RS06360 (ACH6FO_06360) ciaC 1219370..1219690 (+) 321 WP_002866237.1 invasion antigen CiaC -
  ACH6FO_RS06365 (ACH6FO_06365) hemE 1219870..1220892 (+) 1023 WP_002866238.1 uroporphyrinogen decarboxylase -
  ACH6FO_RS06370 (ACH6FO_06370) - 1220889..1221791 (+) 903 WP_002866239.1 radical SAM protein -
  ACH6FO_RS06375 (ACH6FO_06375) - 1221788..1222984 (-) 1197 WP_012006741.1 hypothetical protein -
  ACH6FO_RS06380 (ACH6FO_06380) uvrC 1222986..1224788 (-) 1803 WP_038817224.1 excinuclease ABC subunit UvrC Machinery gene
  ACH6FO_RS06385 (ACH6FO_06385) - 1224781..1225275 (-) 495 WP_002866244.1 hypothetical protein -
  ACH6FO_RS06390 (ACH6FO_06390) guaA 1225414..1226949 (+) 1536 WP_002866245.1 glutamine-hydrolyzing GMP synthase -
  ACH6FO_RS06395 (ACH6FO_06395) - 1227035..1228495 (+) 1461 WP_002866246.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69744.82 Da        Isoelectric Point: 9.3105

>NTDB_id=952127 ACH6FO_RS06380 WP_038817224.1 1222986..1224788(-) (uvrC) [Campylobacter jejuni strain YH028]
MTKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVDFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISREKYLEILDEAMHALLNPSILIKNLEKQMLVLAQNENYEEAAKVRDQIVTIKDLEV
KVEIDIAKLEDFEVFALAFENSMLSTLRFVVQNGKIISVNSKITPIKNDIQWDKNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRMLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKSYFELENLPNDIEIFDNS
HLQGVANVGAMVTYSANSWDKSKYRKFHLKHKNDYDQMREVLMRRVLDFDKIPPPDLWLIDGGKALLDLAKEIIVSSGAN
VDILAISKEKIDAKAHRAKGGARDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLNSSKLVNLGLS
SGVIQKLLAYYGNFESIYKADFKDLAMLVGKKVAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=952127 ACH6FO_RS06380 WP_038817224.1 1222986..1224788(-) (uvrC) [Campylobacter jejuni strain YH028]
TTGACTAAAGAGAATTTAGAAAATGAGTTAAAAACTCTTCCTAATAGTGCTGGAGTGTATCAATATTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGTAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTCGCTTTTACTCCAAATTTACATG
CAAACCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATCACTACTAATTCAGAA
GCCGATGCTTTGATTTTGGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTACTAAGAGATGATAAAAC
TTATCCTTATATTTATGTGGATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGTCTTGCGCCTTGTGATAAACGCATTAGCAGGGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCGCTTTTAAATCCTAGTATTTTAATAAAAAATTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTATGAAGAAGCAGCTAAAGTAAGAGATCAGATTGTAACGATTAAGGATTTAGAAGTT
AAGGTTGAAATAGATATTGCAAAATTAGAAGATTTTGAAGTATTTGCTTTAGCTTTTGAAAATTCCATGCTTTCAACCTT
GCGTTTTGTAGTGCAAAATGGAAAAATTATCAGTGTAAATTCTAAGATTACTCCTATAAAAAATGATATACAATGGGATA
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAATGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTCTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGATAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGTGCAAATTCTTGGGATAAGTCAAAATATCGCAAATT
TCATTTAAAACATAAAAATGATTATGATCAAATGCGTGAAGTTTTAATGCGTAGGGTTTTGGACTTTGATAAAATACCCC
CTCCTGATTTATGGCTTATAGATGGAGGCAAGGCTTTGCTTGATTTGGCTAAAGAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGGGCTAAAGGAGGTGCTAGAGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGCCTAAGTATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCGCATC
GTTTTGCTATCAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAATAGTTCTAAGCTTGTAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTGCAAT
GCTTGTAGGCAAGAAAGTGGCACAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-537)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

45.791

99

0.453