Detailed information NTG0951737

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ACG4I5_RS11560
• Genome accession: NZ_CP172325
• Coordinates: 2514233..2517055 (-)
• Length: 940 a.a.
• NCBI ID: WP_000357696.1
• Uniprot ID: Q9KUW5
• Organism: Vibrio cholerae strain M812
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2509233..2522055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACG4I5_RS11545	lysC	2509368..2510723 (-)	1356	WP_000102995.1	lysine-sensitive aspartokinase 3	-
ACG4I5_RS11550	-	2511187..2512305 (+)	1119	WP_000155556.1	alanine--glyoxylate aminotransferase family protein	-
ACG4I5_RS11555	-	2512384..2514168 (-)	1785	WP_000212615.1	oligosaccharyltransferase	-
ACG4I5_RS11560	uvrA	2514233..2517055 (-)	2823	WP_000357696.1	excinuclease ABC subunit UvrA	Machinery gene
ACG4I5_RS11565	galU	2517211..2518083 (-)	873	WP_001920788.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
ACG4I5_RS11570	qstR	2518256..2518900 (-)	645	WP_001188316.1	LuxR C-terminal-related transcriptional regulator	Regulator
ACG4I5_RS11575	ssb	2519192..2519725 (+)	534	WP_000168289.1	single-stranded DNA-binding protein	Machinery gene
ACG4I5_RS11580	csrD	2519849..2521861 (+)	2013	WP_165967290.1	RNase E specificity factor CsrD	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 104327.86 Da
• Isoelectric Point: 6.4814

>NTDB_id=951737 ACG4I5_RS11560 WP_000357696.1 2514233..2517055(-) (uvrA) [Vibrio cholerae strain M812]
MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG
EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD
GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML
TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI
SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG
PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV
SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES
RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD
PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH
GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN

Nucleotide

• Length: 2823 bp

>NTDB_id=951737 ACG4I5_RS11560 WP_000357696.1 2514233..2517055(-) (uvrA) [Vibrio cholerae strain M812]
ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT
TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG
TCGAATCACTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCATATTGAGGGGCTTTCA
CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACGATTACGGAAGTGTATGACTA
TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGCCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC
AGATGGTAGACAAAGTATTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC
GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC
CGATCCACCGAAACTCGAACTGCACAAAAAGCATACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC
AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTGGAACTTTCCGGCGGTATCGTCGTTGTCGCCCCGATGGAAGGCGAT
GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAACTTGAACCACGCCTGTT
CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA
TTCAAGATGCCAATTTAAGTTTGGCACAAGGTGCGATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG
ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACGCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT
GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTTAAAAAACATCCTTTTG
AAGGAATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTACGTGAGGAGCTGGCAAAATACATC
TCCAACAAGCCTTGCAGCAGCTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGCT
GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA
TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG
CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGTATTCGTCTAGCCAGTCAGATTGGTGCGGGTTTAGTCGGTGT
GATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGCTGCAAACCCTCACCCACTTAC
GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC
CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC
AGGTCAATATCTCAGTGGCGTGAAAAAAATCGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC
TTAAAGGCGCAGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT
TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACAGCACTCAATGGCGCGACGACGGC
GACACCTGCGCCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC
GCACTCCTCGCTCCAACCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTATTTGCAGGAACACAAGAGTCT
CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTTAACGTCCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT
GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAACGCTATAACCGAGAAA
CACTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC
CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGATTGTCCTACATTCGTCTTGGGCAATCAGCCAC
CACCTTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCGCGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA
TTTTGGATGAACCAACCACGGGCCTACACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT
GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGACTGGATCATCGATTTAGGCCCCGAAGG
CGGCCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT
TCCTCAAGCCTTTGTTGAATTAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-236)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-398)

• ABC transporter (ABC_tran) (622-859)

3D structure

• AlphaFold DB: Q9KUW5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.9	100	0.581
uvrA	Streptococcus pneumoniae TIGR4	57.9	100	0.581
uvrA	Streptococcus pneumoniae D39	57.9	100	0.581