Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   WHO22_RS06365 Genome accession   NZ_CP148122
Coordinates   1228653..1229309 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis isolate FELIX_MS513     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1223653..1234309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHO22_RS06335 oppF 1224118..1225035 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  WHO22_RS06340 yjbB 1225142..1226359 (+) 1218 WP_010886478.1 MFS transporter -
  WHO22_RS06345 yjbC 1226523..1227101 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  WHO22_RS06350 spx 1227282..1227677 (+) 396 WP_003245483.1 transcriptional regulator Spx -
  WHO22_RS06355 yjbE 1227720..1228376 (-) 657 WP_003232944.1 TerC family protein -
  WHO22_RS06360 - 1228546..1228686 (+) 141 WP_119122854.1 hypothetical protein -
  WHO22_RS06365 mecA 1228653..1229309 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  WHO22_RS06370 - 1229304..1229426 (-) 123 WP_003245684.1 hypothetical protein -
  WHO22_RS06375 coiA 1229470..1230621 (+) 1152 WP_003245839.1 competence protein CoiA Machinery gene
  WHO22_RS06380 pepF 1230851..1232680 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  WHO22_RS06385 - 1232718..1232885 (-) 168 WP_003244944.1 hypothetical protein -
  WHO22_RS06390 spxH 1233199..1234098 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=951213 WHO22_RS06365 WP_003245194.1 1228653..1229309(+) (mecA) [Bacillus subtilis isolate FELIX_MS513]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=951213 WHO22_RS06365 WP_003245194.1 1228653..1229309(+) (mecA) [Bacillus subtilis isolate FELIX_MS513]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1