Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   AABA08_RS04855 Genome accession   NZ_AP028602
Coordinates   965155..965619 (+) Length   154 a.a.
NCBI ID   WP_001135779.1    Uniprot ID   A4L7M1
Organism   Streptococcus pneumoniae strain PF2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 960155..970619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA08_RS04830 - 962309..962383 (+) 75 Protein_956 dihydroxyacetone kinase subunit L -
  AABA08_RS04835 (TKY092604_09550) - 962383..962490 (+) 108 Protein_957 hypothetical protein -
  AABA08_RS04840 (TKY092604_09560) - 962980..963693 (+) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  AABA08_RS04845 (TKY092604_09570) - 963707..964354 (+) 648 WP_001824648.1 hypothetical protein -
  AABA08_RS04850 (TKY092604_09580) - 964492..965145 (+) 654 WP_001842193.1 uracil-DNA glycosylase -
  AABA08_RS04855 (TKY092604_09590) mutX 965155..965619 (+) 465 WP_001135779.1 NUDIX hydrolase Machinery gene
  AABA08_RS04860 (TKY092604_09600) - 965632..966900 (+) 1269 WP_000924504.1 dihydroorotase -
  AABA08_RS04865 (TKY092604_09610) - 966914..967174 (+) 261 WP_001105922.1 hypothetical protein -
  AABA08_RS04870 (TKY092604_09620) pdrM 967185..968546 (+) 1362 WP_000278535.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  AABA08_RS04875 (TKY092604_09630) - 968700..969668 (+) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17802.12 Da        Isoelectric Point: 4.2287

>NTDB_id=95117 AABA08_RS04855 WP_001135779.1 965155..965619(+) (mutX) [Streptococcus pneumoniae strain PF2]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTSDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=95117 AABA08_RS04855 WP_001135779.1 965155..965619(+) (mutX) [Streptococcus pneumoniae strain PF2]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACATCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7M1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.052

100

0.981

Multiple sequence alignment