Detailed information NTG0950354

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR46_RS14160
• Genome accession: NZ_CP148079
• Coordinates: 2792767..2793654 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN155-2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2787767..2798654

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR46_RS14130 (UXR46_14130)	-	2787786..2787878 (+)	93	WP_010956583.1	hypothetical protein	-
UXR46_RS14135 (UXR46_14135)	-	2787986..2788483 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR46_RS14140 (UXR46_14140)	-	2788493..2788753 (-)	261	WP_001789910.1	hypothetical protein	-
UXR46_RS14145 (UXR46_14145)	-	2789135..2789248 (-)	114	WP_001791776.1	hypothetical protein	-
UXR46_RS14150 (UXR46_14150)	-	2789907..2791907 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR46_RS14155 (UXR46_14155)	-	2791904..2792659 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR46_RS14160 (UXR46_14160)	braS	2792767..2793654 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR46_RS14165 (UXR46_14165)	braR	2793665..2794330 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR46_RS14170 (UXR46_14170)	-	2794356..2794556 (-)	201	WP_000604728.1	hypothetical protein	-
UXR46_RS14175 (UXR46_14175)	-	2794754..2796178 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR46_RS14820	-	2796238..2796339 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR46_RS14185 (UXR46_14185)	-	2796461..2796916 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR46_RS14190 (UXR46_14190)	-	2797161..2797922 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=950354 UXR46_RS14160 WP_000143419.1 2792767..2793654(-) (braS) [Staphylococcus aureus strain BSN155-2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=950354 UXR46_RS14160 WP_000143419.1 2792767..2793654(-) (braS) [Staphylococcus aureus strain BSN155-2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997