Detailed information NTG0950289

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR73_RS08295
• Genome accession: NZ_CP148076
• Coordinates: 1635933..1636976 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN155
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1630933..1641976

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR73_RS08265 (UXR73_08265)	-	1631303..1631413 (+)	111	WP_001790257.1	hypothetical protein	-
UXR73_RS08270 (UXR73_08270)	-	1631442..1631855 (+)	414	WP_001549145.1	hypothetical protein	-
UXR73_RS08275 (UXR73_08275)	-	1632345..1633331 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXR73_RS08280 (UXR73_08280)	map	1633859..1634617 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR73_RS08285 (UXR73_08285)	-	1634834..1635220 (+)	387	WP_001110179.1	hypothetical protein	-
UXR73_RS08290 (UXR73_08290)	liaF	1635235..1635936 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR73_RS08295 (UXR73_08295)	vraS	1635933..1636976 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR73_RS08300 (UXR73_08300)	vraR	1636966..1637595 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXR73_RS08305 (UXR73_08305)	-	1637711..1638928 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXR73_RS08310 (UXR73_08310)	-	1639206..1639481 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR73_RS08315 (UXR73_08315)	-	1639488..1639952 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR73_RS08320 (UXR73_08320)	-	1640099..1640299 (+)	201	WP_000180461.1	DUF1128 family protein	-
UXR73_RS08325 (UXR73_08325)	-	1640302..1641558 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=950289 UXR73_RS08295 WP_001017131.1 1635933..1636976(+) (vraS) [Staphylococcus aureus strain BSN155]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=950289 UXR73_RS08295 WP_001017131.1 1635933..1636976(+) (vraS) [Staphylococcus aureus strain BSN155]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1