Detailed information NTG0948870

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR49_RS12830
• Genome accession: NZ_CP147831
• Coordinates: 2598227..2599114 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BSN140
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2593227..2604114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR49_RS12800 (UXR49_12800)	-	2593245..2593337 (+)	93	WP_010956583.1	hypothetical protein	-
UXR49_RS12805 (UXR49_12805)	-	2593445..2593942 (-)	498	WP_001065269.1	glutathione peroxidase	-
UXR49_RS12810 (UXR49_12810)	-	2593952..2594212 (-)	261	WP_001789910.1	hypothetical protein	-
UXR49_RS12815 (UXR49_12815)	-	2594594..2594707 (-)	114	Protein_2482	hypothetical protein	-
UXR49_RS12820 (UXR49_12820)	-	2595366..2597366 (-)	2001	WP_000776739.1	ABC transporter permease	-
UXR49_RS12825 (UXR49_12825)	-	2597363..2598118 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXR49_RS12830 (UXR49_12830)	braS	2598227..2599114 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR49_RS12835 (UXR49_12835)	braR	2599125..2599790 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR49_RS12840 (UXR49_12840)	-	2599816..2600016 (-)	201	WP_000604727.1	hypothetical protein	-
UXR49_RS12845 (UXR49_12845)	-	2600214..2601638 (+)	1425	WP_000953762.1	alkaline phosphatase	-
UXR49_RS13410	-	2601698..2601799 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR49_RS12855 (UXR49_12855)	-	2601921..2602376 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR49_RS12860 (UXR49_12860)	-	2602621..2603382 (-)	762	WP_000323447.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=948870 UXR49_RS12830 WP_000143420.1 2598227..2599114(-) (braS) [Staphylococcus aureus strain BSN140]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=948870 UXR49_RS12830 WP_000143420.1 2598227..2599114(-) (braS) [Staphylococcus aureus strain BSN140]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993