Detailed information NTG0948865

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXR49_RS09295
• Genome accession: NZ_CP147831
• Coordinates: 1900991..1902034 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN140
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1895991..1907034

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR49_RS09265 (UXR49_09265)	-	1896413..1897669 (-)	1257	WP_001789555.1	aminopeptidase	-
UXR49_RS09270 (UXR49_09270)	-	1897672..1897872 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXR49_RS09275 (UXR49_09275)	-	1898019..1898483 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXR49_RS09280 (UXR49_09280)	-	1898490..1898765 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXR49_RS09285 (UXR49_09285)	-	1899043..1900260 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
UXR49_RS09290 (UXR49_09290)	vraR	1900372..1901001 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXR49_RS09295 (UXR49_09295)	vraS	1900991..1902034 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXR49_RS09300 (UXR49_09300)	liaF	1902031..1902732 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXR49_RS09305 (UXR49_09305)	-	1902747..1903133 (-)	387	WP_001110179.1	hypothetical protein	-
UXR49_RS09310 (UXR49_09310)	map	1903350..1904108 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXR49_RS09315 (UXR49_09315)	-	1904636..1905622 (+)	987	WP_000999714.1	FUSC family protein	-
UXR49_RS09320 (UXR49_09320)	-	1906053..1906466 (-)	414	WP_025173836.1	hypothetical protein	-
UXR49_RS09325 (UXR49_09325)	-	1906495..1906605 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=948865 UXR49_RS09295 WP_001017131.1 1900991..1902034(-) (vraS) [Staphylococcus aureus strain BSN140]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=948865 UXR49_RS09295 WP_001017131.1 1900991..1902034(-) (vraS) [Staphylococcus aureus strain BSN140]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1