Detailed information NTG0948104

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ38_RS09895
• Genome accession: NZ_CP147691
• Coordinates: 1994426..1995469 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN102
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1989426..2000469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ38_RS09865 (UXQ38_09865)	-	1989844..1991100 (-)	1257	WP_001795438.1	aminopeptidase	-
UXQ38_RS09870 (UXQ38_09870)	-	1991103..1991303 (-)	201	WP_000180461.1	DUF1128 family protein	-
UXQ38_RS09875 (UXQ38_09875)	-	1991450..1991914 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ38_RS09880 (UXQ38_09880)	-	1991921..1992196 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ38_RS09885 (UXQ38_09885)	-	1992474..1993691 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ38_RS09890 (UXQ38_09890)	vraR	1993807..1994436 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ38_RS09895 (UXQ38_09895)	vraS	1994426..1995469 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ38_RS09900 (UXQ38_09900)	liaF	1995466..1996167 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ38_RS09905 (UXQ38_09905)	-	1996182..1996568 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ38_RS09910 (UXQ38_09910)	map	1996785..1997543 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ38_RS09915 (UXQ38_09915)	-	1998071..1999057 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ38_RS09920 (UXQ38_09920)	-	1999488..1999901 (-)	414	WP_001549145.1	hypothetical protein	-
UXQ38_RS09925 (UXQ38_09925)	-	1999930..2000040 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=948104 UXQ38_RS09895 WP_001017131.1 1994426..1995469(-) (vraS) [Staphylococcus aureus strain BSN102]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=948104 UXQ38_RS09895 WP_001017131.1 1994426..1995469(-) (vraS) [Staphylococcus aureus strain BSN102]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1