Detailed information NTG0946545

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXR82_RS14020
• Genome accession: NZ_CP147506
• Coordinates: 2756948..2757835 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN139
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2751948..2762835

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXR82_RS13990 (UXR82_13990)	-	2751967..2752059 (+)	93	WP_010956583.1	hypothetical protein	-
UXR82_RS13995 (UXR82_13995)	-	2752167..2752664 (-)	498	WP_001065268.1	glutathione peroxidase	-
UXR82_RS14000 (UXR82_14000)	-	2752674..2752934 (-)	261	WP_001789910.1	hypothetical protein	-
UXR82_RS14005 (UXR82_14005)	-	2753316..2753429 (-)	114	WP_001791776.1	hypothetical protein	-
UXR82_RS14010 (UXR82_14010)	-	2754088..2756088 (-)	2001	WP_000776751.1	ABC transporter permease	-
UXR82_RS14015 (UXR82_14015)	-	2756085..2756840 (-)	756	WP_338748366.1	ABC transporter ATP-binding protein	-
UXR82_RS14020 (UXR82_14020)	braS	2756948..2757835 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXR82_RS14025 (UXR82_14025)	braR	2757846..2758511 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXR82_RS14030 (UXR82_14030)	-	2758537..2758737 (-)	201	WP_000604728.1	hypothetical protein	-
UXR82_RS14035 (UXR82_14035)	-	2758935..2760359 (+)	1425	WP_000953744.1	alkaline phosphatase	-
UXR82_RS14580	-	2760419..2760520 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXR82_RS14045 (UXR82_14045)	-	2760642..2761097 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXR82_RS14050 (UXR82_14050)	-	2761342..2762103 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=946545 UXR82_RS14020 WP_000143419.1 2756948..2757835(-) (braS) [Staphylococcus aureus strain BSN139]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=946545 UXR82_RS14020 WP_000143419.1 2756948..2757835(-) (braS) [Staphylococcus aureus strain BSN139]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997