Detailed information NTG0945951

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: ACFX5S_RS23095
• Genome accession: NZ_CP171242
• Coordinates: 4789995..4791020 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli Nissle 1917
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4784995..4796020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFX5S_RS23075 (ACFX5S_23070)	metJ	4786180..4786497 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
ACFX5S_RS23080 (ACFX5S_23075)	yiiX	4786557..4787165 (+)	609	WP_000702296.1	YiiX family permuted papain-like enzyme	-
ACFX5S_RS23085 (ACFX5S_23080)	rpmE	4787226..4787438 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
ACFX5S_RS23090 (ACFX5S_23085)	priA	4787641..4789839 (+)	2199	WP_001305041.1	primosomal protein N'	Machinery gene
ACFX5S_RS23095 (ACFX5S_23090)	cytR	4789995..4791020 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
ACFX5S_RS23100 (ACFX5S_23095)	ftsN	4791112..4792071 (+)	960	WP_000068846.1	cell division protein FtsN	-
ACFX5S_RS23105 (ACFX5S_23100)	hslV	4792164..4792694 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
ACFX5S_RS23110 (ACFX5S_23105)	hslU	4792704..4794035 (+)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
ACFX5S_RS23115 (ACFX5S_23110)	menA	4794102..4795028 (+)	927	WP_001305044.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
ACFX5S_RS23120 (ACFX5S_23115)	rraA	4795121..4795606 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
ACFX5S_RS23125 (ACFX5S_23120)	zapB	4795691..4795936 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=945951 ACFX5S_RS23095 WP_000644904.1 4789995..4791020(+) (cytR) [Escherichia coli Nissle 1917]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=945951 ACFX5S_RS23095 WP_000644904.1 4789995..4791020(+) (cytR) [Escherichia coli Nissle 1917]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACTCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCACAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACTATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACAGTTCATATAGACAATCTGACCGCCGCATTTGATGCAGTAAATTATCTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGTTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628