Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V7A40_RS02185 Genome accession   NZ_CP146750
Coordinates   444686..446176 (+) Length   496 a.a.
NCBI ID   WP_014024351.1    Uniprot ID   A0AA46TWW1
Organism   Lactococcus garvieae strain L2     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 439686..451176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V7A40_RS02160 (V7A40_02160) pfkB 439833..440759 (+) 927 WP_004259111.1 1-phosphofructokinase -
  V7A40_RS02165 (V7A40_02165) - 440774..442678 (+) 1905 WP_341785223.1 fructose-specific PTS transporter subunit EIIC -
  V7A40_RS02170 (V7A40_02170) - 442790..443032 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  V7A40_RS02175 (V7A40_02175) - 443249..443800 (+) 552 WP_014024349.1 DUF177 domain-containing protein -
  V7A40_RS02180 (V7A40_02180) covR 443902..444597 (+) 696 WP_004259096.1 response regulator transcription factor Regulator
  V7A40_RS02185 (V7A40_02185) covS 444686..446176 (+) 1491 WP_014024351.1 HAMP domain-containing histidine kinase Regulator
  V7A40_RS02190 (V7A40_02190) - 446573..448144 (+) 1572 WP_014024352.1 ABC transporter permease subunit -
  V7A40_RS02195 (V7A40_02195) - 448145..448882 (+) 738 WP_341784714.1 amino acid ABC transporter ATP-binding protein -
  V7A40_RS02200 (V7A40_02200) murD 449021..450382 (+) 1362 WP_014024354.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56753.73 Da        Isoelectric Point: 5.1966

>NTDB_id=944143 V7A40_RS02185 WP_014024351.1 444686..446176(+) (covS) [Lactococcus garvieae strain L2]
MVKFFDSKKKKTESLPERKRSIMLRWAFANTIFCFITFTIFTVLVYQLTITTFINSEKEDMMKALDNVEQSLSQSESTLS
EENLANYLAYAKDYTASSQGKENELETLGSMIGSRKSFYVFDVGENLIYSTNSHGFPLKKDVGDGTHAVRTFGEYSGYLV
ERPVYSNKTGKLIGYVQAFYDMSYYYSVRTKLLIALIILEIIALFIAQFVGYFMASRYIKPLERLHDAITTRANNLKADF
KPVVIQTGDEIEELATVYNDMMIKLNDYVDQQKRFVSDVSHELRTPLAVLDGHLNLLNRWGKNDPEVLEESLQASIEEVS
TMRTMLEEMLALARLENIDFQDEDLICDPTEVSNFLKKNFLLIHADLSLTVENNLSPGRLAHIYPNHYEQGLKILIDNAI
KYSPKDRQEVKIHLEEDDKYIITTVEDHGYGISQEDLKHVFERFFRADKARNRDIGGTGLGLSIIQRIVENYDGDVSVTS
VVGEGSKFTLKIPKIK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=944143 V7A40_RS02185 WP_014024351.1 444686..446176(+) (covS) [Lactococcus garvieae strain L2]
ATGGTAAAATTTTTTGATTCGAAGAAGAAAAAAACAGAAAGTCTTCCCGAGCGTAAGCGAAGCATCATGCTCCGTTGGGC
ATTTGCAAATACGATTTTTTGTTTTATTACCTTCACTATTTTTACAGTATTGGTTTATCAATTGACCATTACAACCTTCA
TCAATTCTGAAAAAGAGGATATGATGAAAGCTCTGGATAATGTTGAGCAAAGTTTGTCCCAATCGGAAAGCACACTGTCG
GAAGAAAATCTGGCGAATTATTTGGCTTATGCCAAAGACTATACAGCCTCCAGTCAGGGAAAAGAAAATGAGCTAGAAAC
ACTTGGAAGTATGATTGGCTCTAGGAAGTCCTTTTATGTTTTTGACGTCGGTGAAAATTTGATTTACTCGACCAATTCGC
ATGGCTTCCCTCTAAAAAAAGACGTGGGGGATGGCACTCATGCTGTACGTACATTTGGTGAATATTCTGGTTATTTGGTC
GAACGACCGGTTTATTCTAATAAAACAGGTAAGCTGATTGGCTATGTGCAGGCTTTCTATGATATGAGTTATTATTATAG
CGTGCGAACAAAGTTACTGATTGCCCTGATTATCCTAGAAATTATTGCTCTCTTTATCGCTCAGTTTGTTGGTTATTTTA
TGGCGAGTCGTTACATCAAGCCTCTAGAACGGTTGCACGATGCGATTACTACACGTGCCAATAACTTGAAGGCGGATTTC
AAACCTGTAGTGATTCAAACAGGTGATGAAATTGAAGAACTGGCGACTGTTTATAATGACATGATGATCAAGCTTAACGA
TTATGTTGATCAGCAGAAACGTTTTGTTTCTGATGTCAGTCACGAGTTACGTACGCCACTTGCGGTTTTGGATGGTCATT
TGAATCTCTTGAACCGTTGGGGGAAAAACGATCCTGAGGTGCTTGAGGAGTCTTTACAGGCCAGTATAGAAGAAGTGAGT
ACGATGAGAACGATGTTGGAAGAGATGCTTGCATTGGCCCGTCTTGAAAACATTGATTTTCAAGATGAAGACCTTATCTG
TGATCCAACAGAAGTTTCTAATTTCCTTAAGAAAAACTTCCTACTTATCCATGCTGATTTAAGCTTAACTGTGGAAAATA
ACTTGTCACCGGGAAGATTGGCTCATATCTATCCCAACCATTATGAACAAGGCTTAAAAATTTTGATTGATAATGCGATA
AAATACTCGCCTAAAGATCGCCAAGAAGTGAAAATCCATCTAGAAGAAGATGATAAATACATTATCACTACGGTTGAGGA
TCATGGCTATGGCATTAGTCAGGAAGATTTAAAACATGTCTTTGAGCGTTTCTTCCGTGCTGATAAAGCGCGAAATCGGG
ATATAGGAGGCACTGGGCTTGGACTGTCTATTATCCAACGCATAGTGGAAAACTATGATGGGGATGTCAGTGTGACTTCT
GTTGTAGGTGAGGGATCGAAATTCACTTTAAAAATTCCTAAGATTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(272-337)

ArlS sensor domain (ArlS_N)

(52-190)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(389-494)

HAMP domain (HAMP)

(214-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

55.936

100

0.56