Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   V7A39_RS07360 Genome accession   NZ_CP146749
Coordinates   1467776..1469890 (+) Length   704 a.a.
NCBI ID   WP_031559418.1    Uniprot ID   -
Organism   Lactococcus petauri strain L3     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1466268..1505428 1467776..1469890 within 0
IScluster/Tn 1459179..1494983 1467776..1469890 within 0


Gene organization within MGE regions


Location: 1459179..1505428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V7A39_RS07335 (V7A39_07335) - 1459999..1462359 (-) 2361 WP_341784996.1 mucin-binding protein -
  V7A39_RS07340 (V7A39_07340) - 1462474..1463371 (+) 898 Protein_1451 IS982 family transposase -
  V7A39_RS10460 - 1463784..1463855 (-) 72 WP_370569341.1 KxYKxGKxW signal peptide domain-containing protein -
  V7A39_RS07345 (V7A39_07345) - 1464078..1466135 (+) 2058 WP_341784997.1 heavy metal translocating P-type ATPase -
  V7A39_RS07350 (V7A39_07350) - 1466268..1466948 (+) 681 WP_285013972.1 IS6 family transposase -
  V7A39_RS07355 (V7A39_07355) - 1467058..1467555 (-) 498 WP_154413824.1 GNAT family N-acetyltransferase -
  V7A39_RS07360 (V7A39_07360) clpC 1467776..1469890 (+) 2115 WP_031559418.1 ATP-dependent protease ClpL Regulator
  V7A39_RS07365 (V7A39_07365) - 1469947..1470627 (-) 681 WP_341784998.1 IS6-like element IS1216 family transposase -
  V7A39_RS07370 (V7A39_07370) - 1470753..1471052 (-) 300 WP_003134227.1 hypothetical protein -
  V7A39_RS07375 (V7A39_07375) - 1471055..1471822 (-) 768 WP_003134226.1 ParA family protein -
  V7A39_RS07380 (V7A39_07380) - 1471916..1472488 (-) 573 WP_003134225.1 recombinase family protein -
  V7A39_RS07385 (V7A39_07385) - 1472890..1473075 (+) 186 WP_165719067.1 hypothetical protein -
  V7A39_RS07390 (V7A39_07390) - 1473107..1473406 (+) 300 WP_165719066.1 hypothetical protein -
  V7A39_RS07395 (V7A39_07395) - 1473500..1473712 (+) 213 WP_165719065.1 garvicin Q family class II bacteriocin -
  V7A39_RS07400 (V7A39_07400) - 1473736..1474050 (+) 315 WP_032495339.1 bacteriocin immunity protein -
  V7A39_RS10465 - 1474177..1474281 (+) 105 WP_405023571.1 cysteine peptidase family C39 domain-containing protein -
  V7A39_RS07405 (V7A39_07405) - 1474319..1474999 (+) 681 WP_013646119.1 IS6-like element IS1216 family transposase -
  V7A39_RS07410 (V7A39_07410) - 1475545..1475712 (-) 168 WP_005228365.1 cysteine-rich KTR domain-containing protein -
  V7A39_RS07415 (V7A39_07415) tet(S) 1475800..1477740 (-) 1941 WP_002405437.1 tetracycline resistance ribosomal protection protein Tet(S) -
  V7A39_RS10470 - 1477725..1477850 (+) 126 WP_193393255.1 hypothetical protein -
  V7A39_RS07420 (V7A39_07420) - 1478569..1478772 (-) 204 WP_017370349.1 conjugal transfer protein -
  V7A39_RS07425 (V7A39_07425) - 1478856..1479536 (+) 681 WP_013646119.1 IS6-like element IS1216 family transposase -
  V7A39_RS07430 (V7A39_07430) - 1480012..1480392 (-) 381 WP_160214536.1 hypothetical protein -
  V7A39_RS07435 (V7A39_07435) - 1480398..1481180 (-) 783 WP_165712995.1 hypothetical protein -
  V7A39_RS07440 (V7A39_07440) - 1481481..1481774 (-) 294 WP_160214574.1 helix-turn-helix transcriptional regulator -
  V7A39_RS07445 (V7A39_07445) - 1482601..1483032 (-) 432 WP_160214575.1 hypothetical protein -
  V7A39_RS07450 (V7A39_07450) - 1483040..1483957 (-) 918 WP_341784999.1 protein rep -
  V7A39_RS07455 (V7A39_07455) - 1483999..1484679 (+) 681 WP_013646119.1 IS6-like element IS1216 family transposase -
  V7A39_RS07460 (V7A39_07460) - 1484746..1485183 (-) 438 WP_341785000.1 hypothetical protein -
  V7A39_RS07465 (V7A39_07465) - 1485198..1487087 (-) 1890 WP_017369570.1 heavy metal translocating P-type ATPase -
  V7A39_RS07470 (V7A39_07470) - 1487178..1487957 (+) 780 WP_017369569.1 MerR family DNA-binding transcriptional regulator -
  V7A39_RS07475 (V7A39_07475) - 1488010..1488378 (-) 369 Protein_1481 CHAP domain-containing protein -
  V7A39_RS07480 (V7A39_07480) - 1488451..1489131 (+) 681 WP_003106709.1 IS6-like element ISTeha2 family transposase -
  V7A39_RS07485 (V7A39_07485) - 1489483..1491345 (+) 1863 WP_341785001.1 heavy metal translocating P-type ATPase -
  V7A39_RS07490 (V7A39_07490) - 1492048..1492275 (+) 228 WP_019335409.1 heavy-metal-associated domain-containing protein -
  V7A39_RS07495 (V7A39_07495) - 1492324..1492869 (+) 546 WP_019335408.1 DNA-binding protein -
  V7A39_RS07500 (V7A39_07500) - 1492955..1493644 (+) 690 WP_019291977.1 Crp/Fnr family transcriptional regulator -
  V7A39_RS07510 (V7A39_07510) - 1495062..1495259 (-) 198 WP_040087131.1 helix-turn-helix domain-containing protein -
  V7A39_RS07515 (V7A39_07515) - 1495446..1495805 (-) 360 WP_019291578.1 hypothetical protein -
  V7A39_RS07520 (V7A39_07520) - 1495793..1496293 (-) 501 WP_019335597.1 hypothetical protein -
  V7A39_RS07525 (V7A39_07525) - 1496317..1496439 (-) 123 WP_258175758.1 hypothetical protein -
  V7A39_RS07530 (V7A39_07530) - 1496711..1497196 (-) 486 WP_198493846.1 phage tail protein -
  V7A39_RS07535 (V7A39_07535) - 1497303..1497818 (-) 516 WP_213439414.1 DUF6273 domain-containing protein -
  V7A39_RS07540 (V7A39_07540) - 1497840..1497968 (-) 129 WP_255566819.1 hypothetical protein -
  V7A39_RS07545 (V7A39_07545) - 1497965..1498396 (-) 432 WP_029346097.1 hypothetical protein -
  V7A39_RS07550 (V7A39_07550) - 1498513..1498659 (-) 147 WP_232621162.1 hypothetical protein -
  V7A39_RS07555 (V7A39_07555) - 1498674..1498904 (-) 231 WP_232621163.1 hypothetical protein -
  V7A39_RS07560 (V7A39_07560) - 1499157..1501142 (-) 1986 WP_019291582.1 ATP-binding cassette domain-containing protein -
  V7A39_RS07565 (V7A39_07565) - 1501231..1501872 (-) 642 WP_019291583.1 MarR family winged helix-turn-helix transcriptional regulator -
  V7A39_RS07570 (V7A39_07570) cydC 1501972..1503690 (-) 1719 WP_019291584.1 thiol reductant ABC exporter subunit CydC -
  V7A39_RS07575 (V7A39_07575) cydD 1503722..1505428 (-) 1707 WP_019291585.1 thiol reductant ABC exporter subunit CydD -

Sequence

Protein


Download         Length: 704 a.a.        Molecular weight: 77795.22 Da        Isoelectric Point: 4.9547

>NTDB_id=944107 V7A39_RS07360 WP_031559418.1 1467776..1469890(+) (clpC) [Lactococcus petauri strain L3]
MANFYGNDPFFNNDRDDVFNQLFRRMDNQNSERARYLVNGQSLTPDEFAQYRATGKLPQNNKTIEVSKDGKQAVKKGGIL
EKLGTNLTEQARDGLLDPVIGREKEIQETAEILSRRTKNNAILVGDAGVGKTAVVEGLAQAIVAGKVPETIQDKEIYSID
LSSLEAGTQYRGSFEENIKQLVEEVKAAGNIILFFDEIHQILGTGATGGEDGGKGLADIIKPALSRGELSVIGATTQDEY
RNTILKNAALARRFNDVVINEPTAADTLRILQGVKELYEKHHHVVLPDDVLKAAVDYSIQYIPQRTLPDKAIDLIDMTAA
HLAAKNSQTDVETLDQRLKKLEAAKEAAIKAEDFTKAADIKKSIEETKQKIKETDPKEKITATIDDVAQSVERLTGIPVS
DMGANDIERLKNLDKRLKSKVIGQDEAVEMVAKAIRRNRAGFSEGDQPIGSFLFVGPTGVGKTELAKQLALDMFGNENAI
IRLDMSEYADRTAVSKLIGTSAGYVGYEDNANTLTERVRRNPYSIVLLDEIEKADPQVLTLLLQVMDDGRLTDGQGNVIN
FKNTIIIATSNAGFGNEALSGDKQRDQSLMDKLAPFFRPEFLNRFNGIVEFSHLTKQDLSQIVDLMLADVQKTLAKKSIK
LEVTKAAKDWLMEQGYDEAMGARPLRRVIEQQIRDKVTDFYLDHLDVKNLKADLVDAEIVISAA

Nucleotide


Download         Length: 2115 bp        

>NTDB_id=944107 V7A39_RS07360 WP_031559418.1 1467776..1469890(+) (clpC) [Lactococcus petauri strain L3]
ATGGCAAATTTTTACGGAAATGATCCTTTTTTCAACAATGATAGGGATGATGTTTTCAATCAATTATTTCGGCGCATGGA
TAATCAAAATTCGGAGCGTGCACGGTATTTAGTTAATGGACAATCGTTGACACCGGATGAGTTTGCTCAATACCGAGCAA
CTGGTAAGCTACCCCAAAATAATAAAACAATAGAAGTATCTAAAGATGGTAAACAGGCTGTTAAAAAAGGAGGGATTTTA
GAAAAGTTAGGGACCAATTTGACGGAACAGGCTCGTGATGGATTACTAGATCCAGTGATTGGACGTGAGAAAGAGATTCA
AGAAACTGCAGAAATTTTGAGTCGTAGAACGAAAAATAATGCAATCTTAGTTGGTGATGCCGGTGTAGGTAAAACTGCAG
TCGTCGAAGGTCTGGCACAAGCAATTGTGGCTGGTAAAGTTCCAGAAACGATTCAAGATAAAGAAATCTATTCGATTGAT
TTATCGTCTTTGGAAGCGGGAACTCAATATCGCGGTTCTTTTGAAGAAAATATTAAACAGCTGGTAGAGGAAGTTAAAGC
AGCTGGTAATATTATTCTATTCTTCGATGAAATTCATCAGATTCTCGGCACGGGTGCCACTGGTGGTGAAGATGGTGGCA
AAGGATTGGCTGATATCATTAAACCTGCTTTGTCACGTGGCGAGCTGAGTGTAATCGGGGCTACGACTCAAGATGAATAT
CGCAATACTATTTTGAAAAATGCGGCTTTGGCACGGCGATTCAATGATGTTGTGATTAATGAACCGACGGCCGCTGACAC
TTTACGTATATTACAAGGTGTTAAAGAGCTGTACGAAAAACATCATCATGTTGTATTACCAGATGATGTTTTGAAGGCGG
CTGTGGATTATTCAATCCAATATATACCACAACGCACTTTGCCAGATAAAGCTATCGATTTGATCGACATGACTGCGGCT
CATTTAGCGGCTAAAAATTCGCAAACTGATGTTGAGACATTGGATCAACGCCTTAAAAAATTAGAGGCAGCTAAGGAGGC
CGCCATTAAAGCGGAGGACTTTACAAAAGCCGCTGATATCAAGAAGTCGATCGAGGAAACCAAGCAAAAAATTAAAGAAA
CGGATCCAAAAGAAAAAATCACTGCCACGATTGATGATGTGGCACAATCGGTTGAACGTTTAACTGGTATACCAGTTTCT
GATATGGGCGCTAATGATATTGAGCGCTTGAAAAATCTTGATAAGCGTCTGAAAAGTAAGGTAATCGGTCAAGATGAAGC
GGTTGAAATGGTAGCAAAAGCAATTCGGCGTAACCGTGCGGGCTTTTCAGAGGGTGATCAGCCGATTGGAAGTTTTCTGT
TTGTGGGCCCAACTGGCGTAGGAAAGACTGAATTAGCTAAGCAATTAGCCTTAGATATGTTTGGAAATGAAAATGCGATT
ATTCGGCTAGATATGAGTGAATATGCTGATCGTACAGCTGTGTCGAAATTAATTGGTACCTCGGCTGGATACGTAGGCTA
TGAAGATAATGCTAATACTCTAACTGAACGGGTTCGGCGTAATCCATATTCCATTGTATTATTAGATGAAATTGAAAAGG
CTGATCCACAAGTATTAACGTTACTGTTACAAGTGATGGATGATGGGCGCTTAACGGATGGACAAGGCAATGTCATTAAT
TTCAAAAATACGATTATTATTGCTACTTCTAATGCTGGCTTTGGTAATGAAGCATTAAGTGGTGACAAGCAACGAGATCA
GTCATTAATGGATAAGTTAGCACCATTTTTCCGCCCAGAATTTCTGAACCGTTTTAATGGAATCGTGGAATTTTCACATC
TGACTAAGCAAGACTTAAGTCAAATTGTCGATTTGATGTTGGCGGATGTACAAAAAACTTTAGCCAAAAAATCCATCAAA
CTTGAGGTAACTAAAGCGGCCAAAGATTGGCTGATGGAACAAGGCTATGATGAAGCAATGGGTGCGCGGCCATTACGGCG
AGTAATTGAACAACAAATTCGTGATAAGGTAACGGATTTCTACCTTGACCACTTAGATGTCAAAAACTTGAAGGCTGATT
TAGTGGATGCTGAGATTGTGATATCGGCAGCTTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(447-606)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(614-684)

AAA lid domain (AAA_lid_9)

(264-362)

ATPase family associated with various cellular activities (AAA) (AAA)

(122-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.814

100

0.482
  clpE Streptococcus pneumoniae Rx1

51.603

88.636

0.457
  clpE Streptococcus pneumoniae D39

51.603

88.636

0.457
  clpE Streptococcus pneumoniae R6

51.603

88.636

0.457
  clpE Streptococcus mutans UA159

50.235

90.483

0.455
  clpE Streptococcus pneumoniae TIGR4

51.122

88.636

0.453
  clpC Bacillus subtilis subsp. subtilis str. 168

46.154

88.636

0.409
  clpC Streptococcus pneumoniae Rx1

43.78

90.199

0.395
  clpC Streptococcus pneumoniae D39

43.78

90.199

0.395
  clpC Streptococcus thermophilus LMG 18311

44.895

87.642

0.393
  clpC Streptococcus thermophilus LMD-9

44.733

87.642

0.392
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.472

0.391
  clpC Streptococcus mutans UA159

44.032

88.068

0.388
  clpC Streptococcus pneumoniae TIGR4

44.084

87.642

0.386