NTDB

Overview

Name	comGA	Type	Machinery gene
Locus tag	V7A41_RS00690	Genome accession	NZ_CP146746
Coordinates	144967..145911 (+)	Length	314 a.a.
NCBI ID	WP_019291447.1	Uniprot ID	-
Organism	Lactococcus petauri strain L4
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 139967..150911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V7A41_RS00675 (V7A41_00675)	-	141228..142829 (-)	1602	WP_153924348.1	GH25 family lysozyme	-
V7A41_RS00680 (V7A41_00680)	guaB	142998..144479 (+)	1482	WP_003133714.1	IMP dehydrogenase	-
V7A41_RS00685 (V7A41_00685)	rpsU	144605..144781 (+)	177	WP_003134539.1	30S ribosomal protein S21	-
V7A41_RS00690 (V7A41_00690)	comGA	144967..145911 (+)	945	WP_019291447.1	competence type IV pilus ATPase ComGA	Machinery gene
V7A41_RS00695 (V7A41_00695)	comGB	145850..146869 (+)	1020	WP_255566838.1	competence type IV pilus assembly protein ComGB	Machinery gene
V7A41_RS00700 (V7A41_00700)	comYC	146888..147193 (+)	306	WP_153924350.1	competence type IV pilus major pilin ComGC	Machinery gene
V7A41_RS00705 (V7A41_00705)	comGD	147168..147584 (+)	417	WP_019291446.1	competence type IV pilus minor pilin ComGD	Machinery gene
V7A41_RS00710 (V7A41_00710)	comGE	147616..147849 (+)	234	WP_019293009.1	competence type IV pilus minor pilin ComGE	-
V7A41_RS00715 (V7A41_00715)	comGF	147830..148270 (+)	441	WP_019291444.1	competence type IV pilus minor pilin ComGF	-
V7A41_RS00720 (V7A41_00720)	-	148502..149347 (+)	846	WP_019291443.1	metal ABC transporter solute-binding protein, Zn/Mn family	-
V7A41_RS00725 (V7A41_00725)	-	149418..150302 (-)	885	WP_019291442.1	RluA family pseudouridine synthase	-

Sequence

Protein

Download Length: 314 a.a. Molecular weight: 35713.01 Da Isoelectric Point: 6.9700

                                >NTDB_id=944032 V7A41_RS00690 WP_019291447.1 144967..145911(+) (comGA) [Lactococcus petauri strain L4]

MIQVLAKNLLQKAVDQMVHDLYLVALEGKYSLYFRTTTERRFEGELTLEQGQALIAHMKFLSGMNLGESRRVQLGACTYI

LDKGEQRLRLSTVGDFHGQESLVIRLLHHQQNQLHFWNSEIFNTIIGGRGLYLFSGPVGSGKTSLMYKFAREHFKNQQVI

CIEDPVELVENEFLQLQVNKVIGNDYDSLIKLSLRHRPDLLIVGEIRDSQTAKAVLRASLTGYTVFSTVHARSISGVIAR

LKELGLSDWELQSSLQRVIYQRLIAGKGLLVCEKEKFEEWKPDEWNDQIDQLVADGFISAVAAAREKIEFSKAD

Nucleotide

Download Length: 945 bp

                                >NTDB_id=944032 V7A41_RS00690 WP_019291447.1 144967..145911(+) (comGA) [Lactococcus petauri strain L4]

ATGATACAGGTTTTGGCAAAAAACCTTTTACAAAAAGCAGTAGATCAGATGGTGCACGATCTTTATTTAGTAGCATTAGA

AGGAAAGTATTCTCTCTATTTTCGTACAACAACAGAAAGGAGGTTTGAAGGAGAACTCACCCTTGAGCAAGGGCAAGCAC

TGATTGCTCATATGAAATTTTTATCTGGTATGAATCTAGGAGAAAGTAGACGAGTACAGTTGGGGGCTTGCACTTATATC

TTAGATAAAGGTGAGCAGCGCTTACGTTTATCTACTGTCGGTGATTTTCATGGTCAAGAAAGCTTGGTTATTCGACTCTT

GCATCATCAACAAAACCAACTTCATTTTTGGAATTCAGAGATCTTTAATACTATTATTGGGGGAAGAGGCCTTTACCTTT

TTTCAGGTCCTGTAGGTTCAGGTAAGACCAGTCTTATGTACAAATTTGCAAGGGAGCATTTTAAAAATCAACAAGTTATT

TGTATAGAAGATCCTGTGGAGTTAGTAGAAAATGAATTTTTGCAACTTCAAGTCAATAAAGTAATAGGGAATGATTATGA

TTCCTTGATTAAGCTTTCGCTGCGACATAGACCTGATTTACTTATTGTTGGTGAAATTAGGGATAGTCAAACGGCAAAAG

CTGTTCTTCGTGCAAGTTTGACTGGGTATACAGTATTCTCTACTGTTCATGCACGCTCAATATCAGGTGTAATTGCACGC

TTAAAAGAACTTGGATTAAGTGATTGGGAGCTACAATCCAGTCTTCAGCGGGTGATTTATCAACGATTAATTGCAGGAAA

GGGATTGCTTGTTTGTGAAAAGGAAAAGTTTGAAGAATGGAAACCAGACGAATGGAATGACCAGATTGATCAGTTGGTTG

CAGATGGATTTATCTCAGCTGTTGCAGCTGCGCGCGAAAAAATTGAGTTTAGCAAAGCAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-264)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGA	Lactococcus lactis subsp. cremoris KW2	60.191	100	0.602
comYA	Streptococcus gordonii str. Challis substr. CH1	53.651	100	0.538
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	53.035	99.682	0.529
comGA/cglA/cilD	Streptococcus pneumoniae R6	52.716	99.682	0.525
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	52.716	99.682	0.525
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	52.716	99.682	0.525
comGA/cglA/cilD	Streptococcus pneumoniae D39	52.716	99.682	0.525
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	52.564	99.363	0.522
comYA	Streptococcus mutans UA159	50.949	100	0.513
comYA	Streptococcus mutans UA140	50.949	100	0.513

Detailed information NTG0944032