Detailed information NTG0943579

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACFIOT_RS00850
• Genome accession: NZ_CP170414
• Coordinates: 184030..186138 (-)
• Length: 702 a.a.
• NCBI ID: WP_054189847.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain t5047
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 179030..191138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOT_RS00835	-	181546..181773 (+)	228	WP_000932073.1	FeoA family protein	-
ACFIOT_RS00840	feoB	181785..183779 (+)	1995	WP_054189846.1	ferrous iron transport protein B	-
ACFIOT_RS00845	-	183792..183962 (+)	171	WP_000111118.1	FeoB-associated Cys-rich membrane protein	-
ACFIOT_RS00850	clpE	184030..186138 (-)	2109	WP_054189847.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACFIOT_RS00855	-	186501..187022 (+)	522	WP_054189848.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACFIOT_RS00860	-	187192..188358 (-)	1167	WP_054189849.1	hydroxymethylglutaryl-CoA synthase	-
ACFIOT_RS00865	-	188613..189893 (+)	1281	WP_054189850.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACFIOT_RS00870	-	190032..190463 (-)	432	WP_000875614.1	CHAP domain-containing protein	-
ACFIOT_RS00875	-	190855..191070 (-)	216	WP_054189851.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78082.52 Da
• Isoelectric Point: 4.6626

>NTDB_id=943579 ACFIOT_RS00850 WP_054189847.1 184030..186138(-) (clpE) [Staphylococcus aureus strain t5047]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQATQRQLGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVETLKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIIQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=943579 ACFIOT_RS00850 WP_054189847.1 184030..186138(-) (clpE) [Staphylococcus aureus strain t5047]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAACACAAAGACAACTAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACACAAGAAGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTTGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCGCAAGCAATCGTTGAAGGAAATGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCACTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAACTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATACAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGGGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCTAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTAATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTGCTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
TCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.222	92.308	0.436
clpE	Streptococcus pneumoniae Rx1	47.164	87.892	0.415
clpE	Streptococcus pneumoniae D39	47.164	87.892	0.415
clpE	Streptococcus pneumoniae R6	47.164	87.892	0.415
clpE	Streptococcus pneumoniae TIGR4	47.164	87.892	0.415
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	43.578	93.162	0.406
clpC	Streptococcus thermophilus LMD-9	44.373	88.604	0.393
clpC	Streptococcus thermophilus LMG 18311	44.212	88.604	0.392
clpC	Streptococcus pneumoniae TIGR4	42.767	90.598	0.387
clpC	Streptococcus pneumoniae Rx1	42.767	90.598	0.387
clpC	Streptococcus pneumoniae D39	42.767	90.598	0.387
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.678	92.45	0.376