Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   V9Z45_RS02195 Genome accession   NZ_CP146660
Coordinates   454951..456075 (+) Length   374 a.a.
NCBI ID   WP_000228508.1    Uniprot ID   A0A0D8VMA7
Organism   Escherichia coli strain MS 57-2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 449951..461075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9Z45_RS02170 (V9Z45_02170) mscL 450068..450481 (-) 414 WP_000022450.1 large-conductance mechanosensitive channel protein MscL -
  V9Z45_RS02175 (V9Z45_02175) trkA 450611..451987 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  V9Z45_RS02180 (V9Z45_02180) rsmB 452009..453298 (-) 1290 WP_000744764.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  V9Z45_RS02185 (V9Z45_02185) fmt 453350..454297 (-) 948 WP_000004424.1 methionyl-tRNA formyltransferase -
  V9Z45_RS02190 (V9Z45_02190) def 454312..454821 (-) 510 WP_000114984.1 peptide deformylase -
  V9Z45_RS02195 (V9Z45_02195) dprA 454951..456075 (+) 1125 WP_000228508.1 DNA-protecting protein DprA Machinery gene
  V9Z45_RS02200 (V9Z45_02200) smg 456047..456520 (+) 474 WP_000460673.1 DUF494 family protein Smg -
  V9Z45_RS02205 (V9Z45_02205) yrdD 456549..457091 (+) 543 WP_001312137.1 type I DNA topoisomerase -
  V9Z45_RS02210 (V9Z45_02210) tsaC 457096..457668 (+) 573 WP_001296460.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  V9Z45_RS02215 (V9Z45_02215) aroE 457673..458491 (+) 819 WP_000451230.1 shikimate dehydrogenase -
  V9Z45_RS02220 (V9Z45_02220) yrdB 458488..458745 (+) 258 WP_001070567.1 DUF1488 domain-containing protein -
  V9Z45_RS02225 (V9Z45_02225) yrdA 458721..459275 (-) 555 WP_001286206.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40892.82 Da        Isoelectric Point: 6.0395

>NTDB_id=943574 V9Z45_RS02195 WP_000228508.1 454951..456075(+) (dprA) [Escherichia coli strain MS 57-2]
MVDTEIWLRLISISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=943574 V9Z45_RS02195 WP_000228508.1 454951..456075(+) (dprA) [Escherichia coli strain MS 57-2]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATTAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTATCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGCCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAGGGGGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39