NTDB

Overview

Name	irvR	Type	Regulator
Locus tag	ACFIOR_RS03690	Genome accession	NZ_CP170409
Coordinates	739256..739969 (-)	Length	237 a.a.
NCBI ID	WP_001031454.1	Uniprot ID	A0A0H2XG68
Organism	Staphylococcus aureus strain t359
Function	regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 734256..744969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOR_RS03660	sph	735034..735858 (-)	825	Protein_717	sphingomyelin phosphodiesterase	-
ACFIOR_RS03665	-	735915..736952 (-)	1038	WP_000857184.1	tyrosine-type recombinase/integrase	-
ACFIOR_RS03670	-	737011..737475 (-)	465	WP_000825947.1	hypothetical protein	-
ACFIOR_RS03675	-	737575..737757 (-)	183	WP_000705243.1	hypothetical protein	-
ACFIOR_RS03680	-	737961..738302 (-)	342	WP_000591749.1	hypothetical protein	-
ACFIOR_RS03685	-	738308..739240 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
ACFIOR_RS03690	irvR	739256..739969 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
ACFIOR_RS03695	-	739932..740106 (+)	175	Protein_724	transcriptional regulator	-
ACFIOR_RS03700	-	740103..740366 (+)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
ACFIOR_RS03705	-	740382..740597 (+)	216	WP_001025404.1	MW1434 family type I TA system toxin	-
ACFIOR_RS03710	-	740586..740915 (-)	330	WP_000128907.1	hypothetical protein	-
ACFIOR_RS03715	-	740966..741718 (+)	753	WP_113588646.1	phage antirepressor KilAC domain-containing protein	-
ACFIOR_RS03720	-	741734..741931 (+)	198	WP_168768264.1	hypothetical protein	-
ACFIOR_RS03725	-	741918..742298 (-)	381	WP_000762521.1	DUF2513 domain-containing protein	-
ACFIOR_RS03730	-	742353..742676 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
ACFIOR_RS03735	-	742673..742834 (+)	162	WP_000048129.1	DUF1270 family protein	-
ACFIOR_RS03740	-	742927..743187 (+)	261	WP_000291488.1	DUF1108 family protein	-
ACFIOR_RS03745	-	743196..743459 (+)	264	WP_001205732.1	hypothetical protein	-

Sequence

Protein

Download Length: 237 a.a. Molecular weight: 27017.58 Da Isoelectric Point: 5.0545

                                >NTDB_id=943411 ACFIOR_RS03690 WP_001031454.1 739256..739969(-) (irvR) [Staphylococcus aureus strain t359]

MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI

YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV

NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

Download Length: 714 bp

                                >NTDB_id=943411 ACFIOR_RS03690 WP_001031454.1 739256..739969(-) (irvR) [Staphylococcus aureus strain t359]

ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT

TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC

AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA

TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG

AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG

GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA

AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA

AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC

TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
irvR	Streptococcus mutans UA159	33.929	100	0.401

Detailed information NTG0943411