Detailed information NTG0943380

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ACFIOO_RS08975
• Genome accession: NZ_CP170406
• Coordinates: 1863640..1864347 (+)
• Length: 235 a.a.
• NCBI ID: WP_000094093.1
• Uniprot ID: A0A1D4DWM6
• Organism: Staphylococcus aureus strain t21635
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1858640..1869347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOO_RS08925	-	1859595..1859858 (-)	264	WP_001205732.1	hypothetical protein	-
ACFIOO_RS08930	-	1859867..1860127 (-)	261	WP_000291489.1	DUF1108 family protein	-
ACFIOO_RS08935	-	1860220..1860381 (-)	162	WP_000066020.1	DUF1270 domain-containing protein	-
ACFIOO_RS08940	-	1860378..1860698 (-)	321	WP_001120197.1	DUF771 domain-containing protein	-
ACFIOO_RS08945	-	1860757..1861389 (+)	633	WP_000275058.1	hypothetical protein	-
ACFIOO_RS08950	-	1861404..1861544 (-)	141	WP_000939496.1	hypothetical protein	-
ACFIOO_RS08955	-	1861618..1862337 (-)	720	WP_410540922.1	phage antirepressor KilAC domain-containing protein	-
ACFIOO_RS08960	-	1862394..1862933 (+)	540	WP_054190605.1	hypothetical protein	-
ACFIOO_RS08965	-	1862957..1863217 (-)	261	WP_000435341.1	transcriptional regulator	-
ACFIOO_RS08970	-	1863230..1863469 (-)	240	WP_000548578.1	helix-turn-helix transcriptional regulator	-
ACFIOO_RS08975	irvR	1863640..1864347 (+)	708	WP_000094093.1	helix-turn-helix domain-containing protein	Regulator
ACFIOO_RS08980	-	1864359..1864514 (+)	156	WP_001049399.1	hypothetical protein	-
ACFIOO_RS08985	-	1864501..1864686 (+)	186	WP_001089804.1	hypothetical protein	-
ACFIOO_RS08990	-	1864886..1865053 (+)	168	WP_000705238.1	hypothetical protein	-
ACFIOO_RS08995	-	1865193..1865732 (+)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
ACFIOO_RS09000	-	1865905..1866942 (+)	1038	WP_054190606.1	tyrosine-type recombinase/integrase	-
ACFIOO_RS09005	-	1867005..1867598 (-)	594	Protein_1770	restriction endonuclease subunit S	-
ACFIOO_RS09010	-	1867591..1869147 (-)	1557	WP_061745621.1	type I restriction-modification system subunit M	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26769.35 Da
• Isoelectric Point: 5.4082

>NTDB_id=943380 ACFIOO_RS08975 WP_000094093.1 1863640..1864347(+) (irvR) [Staphylococcus aureus strain t21635]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide

• Length: 708 bp

>NTDB_id=943380 ACFIOO_RS08975 WP_000094093.1 1863640..1864347(+) (irvR) [Staphylococcus aureus strain t21635]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (123-234)

• Helix-turn-helix (HTH_3) (8-61)

3D structure

• AlphaFold DB: A0A1D4DWM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	30.769	100	0.374