Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACFIOB_RS08235 Genome accession   NZ_CP170401
Coordinates   1722870..1724144 (+) Length   424 a.a.
NCBI ID   WP_001279338.1    Uniprot ID   A0A0H2XGV4
Organism   Staphylococcus aureus strain t10543     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1717870..1729144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOB_RS08215 - 1719203..1719289 (+) 87 WP_153908661.1 hypothetical protein -
  ACFIOB_RS08220 - 1719250..1720380 (-) 1131 WP_000721726.1 HAD family hydrolase -
  ACFIOB_RS08225 nagE 1720487..1721953 (-) 1467 WP_000276359.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  ACFIOB_RS08230 - 1722081..1722698 (-) 618 WP_000287588.1 lysophospholipid acyltransferase family protein -
  ACFIOB_RS08235 htrA 1722870..1724144 (+) 1275 WP_001279338.1 S1C family serine protease Regulator
  ACFIOB_RS08240 tyrS 1724238..1725500 (-) 1263 WP_000186035.1 tyrosine--tRNA ligase -
  ACFIOB_RS08245 - 1725881..1726786 (+) 906 WP_000184363.1 transglycosylase domain-containing protein -
  ACFIOB_RS08250 - 1726766..1726852 (-) 87 WP_031785424.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45802.98 Da        Isoelectric Point: 9.9696

>NTDB_id=943202 ACFIOB_RS08235 WP_001279338.1 1722870..1724144(+) (htrA) [Staphylococcus aureus strain t10543]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=943202 ACFIOB_RS08235 WP_001279338.1 1722870..1724144(+) (htrA) [Staphylococcus aureus strain t10543]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATCATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTCCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCCGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAATCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGTGAACGTACTATTGACGCAGAGACAACTGGAGGTAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATTGGGTTTGCCATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATAGACCGCCCTTCAATCGGTATTGGATTAATTAATTTGAAAGATATCCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCAAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAGCCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGCCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-269)

PDZ domain (PDZ_2)

(307-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

39.055

94.811

0.37