Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACFIOP_RS08575 Genome accession   NZ_CP170392
Coordinates   1779262..1780536 (+) Length   424 a.a.
NCBI ID   WP_001279338.1    Uniprot ID   A0A0H2XGV4
Organism   Staphylococcus aureus strain t442     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1774262..1785536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOP_RS08555 - 1775586..1775681 (+) 96 WP_031761395.1 hypothetical protein -
  ACFIOP_RS08560 - 1775642..1776772 (-) 1131 WP_000721699.1 HAD family hydrolase -
  ACFIOP_RS08565 nagE 1776879..1778345 (-) 1467 WP_000276367.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  ACFIOP_RS08570 - 1778473..1779090 (-) 618 WP_103152290.1 lysophospholipid acyltransferase family protein -
  ACFIOP_RS08575 htrA 1779262..1780536 (+) 1275 WP_001279338.1 S1C family serine protease Regulator
  ACFIOP_RS08580 tyrS 1780630..1781892 (-) 1263 WP_000186029.1 tyrosine--tRNA ligase -
  ACFIOP_RS08585 - 1782274..1783179 (+) 906 WP_000184370.1 transglycosylase domain-containing protein -
  ACFIOP_RS08590 - 1783159..1783251 (-) 93 WP_031761401.1 hypothetical protein -

Sequence

Protein


Download         Length: 424 a.a.        Molecular weight: 45802.98 Da        Isoelectric Point: 9.9696

>NTDB_id=942934 ACFIOP_RS08575 WP_001279338.1 1779262..1780536(+) (htrA) [Staphylococcus aureus strain t442]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide


Download         Length: 1275 bp        

>NTDB_id=942934 ACFIOP_RS08575 WP_001279338.1 1779262..1780536(+) (htrA) [Staphylococcus aureus strain t442]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(125-269)

PDZ domain (PDZ_2)

(307-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XGV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

39.055

94.811

0.37