Detailed information NTG0942785

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACFIOJ_RS00870
• Genome accession: NZ_CP170391
• Coordinates: 183965..186073 (-)
• Length: 702 a.a.
• NCBI ID: WP_410533243.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain t21642
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 178965..191073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFIOJ_RS00855	-	181481..181708 (+)	228	WP_410533240.1	FeoA family protein	-
ACFIOJ_RS00860	feoB	181720..183714 (+)	1995	WP_410533241.1	ferrous iron transport protein B	-
ACFIOJ_RS00865	-	183727..183897 (+)	171	WP_410533242.1	FeoB-associated Cys-rich membrane protein	-
ACFIOJ_RS00870	clpE	183965..186073 (-)	2109	WP_410533243.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACFIOJ_RS00875	-	186433..186954 (+)	522	WP_054189848.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACFIOJ_RS00880	-	187124..188290 (-)	1167	WP_054189849.1	hydroxymethylglutaryl-CoA synthase	-
ACFIOJ_RS00885	-	188546..189826 (+)	1281	WP_054189850.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACFIOJ_RS00890	-	189965..190396 (-)	432	WP_000875614.1	CHAP domain-containing protein	-
ACFIOJ_RS00895	-	190788..191003 (-)	216	WP_054189851.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78168.78 Da
• Isoelectric Point: 4.6626

>NTDB_id=942785 ACFIOJ_RS00870 WP_410533243.1 183965..186073(-) (clpE) [Staphylococcus aureus strain t21642]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQATQRQLGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEIHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGMDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELIVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=942785 ACFIOJ_RS00870 WP_410533243.1 183965..186073(-) (clpE) [Staphylococcus aureus strain t21642]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAACACAAAGACAACTAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACACAAGAAGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTTGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCGCAAGCAATCGTTGAAGGAAATGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCACTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGTGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAATACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATACAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGGGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCTAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATCA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTTC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTAATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTATGGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAATCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.597	91.88	0.437
clpE	Streptococcus pneumoniae Rx1	47.326	87.892	0.416
clpE	Streptococcus pneumoniae D39	47.326	87.892	0.416
clpE	Streptococcus pneumoniae R6	47.326	87.892	0.416
clpE	Streptococcus pneumoniae TIGR4	47.326	87.892	0.416
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	43.731	93.162	0.407
clpC	Streptococcus thermophilus LMD-9	44.534	88.604	0.395
clpC	Streptococcus thermophilus LMG 18311	44.373	88.604	0.393
clpC	Streptococcus pneumoniae TIGR4	43.15	90.456	0.39
clpC	Streptococcus pneumoniae Rx1	43.15	90.456	0.39
clpC	Streptococcus pneumoniae D39	43.15	90.456	0.39
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.832	92.45	0.377