Detailed information NTG0942074

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: V8H03_RS00360
• Genome accession: NZ_CP146215
• Coordinates: 78003..79631 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain KWT 2016-Z4326
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	58489..80998	78003..79631	within	0

Gene organization within MGE regions

Location: 58489..80998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V8H03_RS00260 (V8H03_00260)	mec	58489..60566 (-)	2078	Protein_49	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase	-
V8H03_RS00265 (V8H03_00265)	mecR1	60663..62420 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
V8H03_RS00270 (V8H03_00270)	mecI	62420..62791 (+)	372	Protein_51	mecA-type methicillin resistance repressor MecI	-
V8H03_RS00275 (V8H03_00275)	psm-mec	62876..62944 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
V8H03_RS00280 (V8H03_00280)	-	63265..64436 (-)	1172	Protein_53	IS256-like element IS256 family transposase	-
V8H03_RS00285 (V8H03_00285)	-	64595..65743 (+)	1149	WP_150854453.1	ROK family transcriptional regulator	-
V8H03_RS00290 (V8H03_00290)	cstB	65857..67191 (-)	1335	Protein_55	persulfide dioxygenase-sulfurtransferase CstB	-
V8H03_RS00295 (V8H03_00295)	-	67223..68287 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
V8H03_RS00300 (V8H03_00300)	cstR	68423..68683 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
V8H03_RS00305 (V8H03_00305)	-	68683..69321 (+)	639	Protein_58	sulfite exporter TauE/SafE family protein	-
V8H03_RS00310 (V8H03_00310)	-	69595..70212 (-)	618	WP_000562107.1	CadD family cadmium resistance transporter	-
V8H03_RS00315 (V8H03_00315)	-	70293..72707 (-)	2415	WP_000378485.1	cadmium-translocating P-type ATPase CadA	-
V8H03_RS00320 (V8H03_00320)	-	72700..73065 (-)	366	WP_000159127.1	metalloregulator ArsR/SmtB family transcription factor	-
V8H03_RS00325 (V8H03_00325)	-	73251..73628 (-)	378	WP_001041908.1	DUF6262 family protein	-
V8H03_RS00330 (V8H03_00330)	-	73635..75527 (-)	1893	WP_338613460.1	site-specific integrase	-
V8H03_RS00335 (V8H03_00335)	-	75722..76045 (-)	324	WP_000088091.1	JAB domain-containing protein	-
V8H03_RS00340 (V8H03_00340)	-	76038..76244 (-)	207	WP_001077283.1	hypothetical protein	-
V8H03_RS00345 (V8H03_00345)	-	76246..76767 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
V8H03_RS00350 (V8H03_00350)	-	76786..77097 (-)	312	WP_000833212.1	DUF960 family protein	-
V8H03_RS00355 (V8H03_00355)	-	77182..77532 (-)	351	WP_000171449.1	SAUGI family uracil-DNA glycosylase inhibitor	-
V8H03_RS00360 (V8H03_00360)	ccrB	78003..79631 (-)	1629	WP_001186596.1	recombinase family protein	Machinery gene
V8H03_RS00365 (V8H03_00365)	ccrA	79652..80998 (-)	1347	WP_000816499.1	recombinase family protein	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=942074 V8H03_RS00360 WP_001186596.1 78003..79631(-) (ccrB) [Staphylococcus aureus strain KWT 2016-Z4326]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=942074 V8H03_RS00360 WP_001186596.1 78003..79631(-) (ccrB) [Staphylococcus aureus strain KWT 2016-Z4326]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAAAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865