Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   V8H05_RS00190 Genome accession   NZ_CP146213
Coordinates   42654..44003 (-) Length   449 a.a.
NCBI ID   WP_338616594.1    Uniprot ID   -
Organism   Staphylococcus aureus strain KWT 2019-23549     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 37654..49003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8H05_RS00160 (V8H05_00160) - 38404..38802 (-) 399 WP_338616790.1 DUF2871 domain-containing protein -
  V8H05_RS00165 (V8H05_00165) - 38977..39197 (-) 221 Protein_30 hypothetical protein -
  V8H05_RS00170 (V8H05_00170) - 39212..39715 (-) 504 WP_338616592.1 DUF1643 domain-containing protein -
  V8H05_RS00175 (V8H05_00175) - 39730..40044 (-) 315 WP_002502952.1 DUF960 family protein -
  V8H05_RS00180 (V8H05_00180) - 40131..40481 (-) 351 WP_002502953.1 SAUGI family uracil-DNA glycosylase inhibitor -
  V8H05_RS00185 (V8H05_00185) ccrB 41004..42632 (-) 1629 WP_338616593.1 recombinase family protein Machinery gene
  V8H05_RS00190 (V8H05_00190) ccrA 42654..44003 (-) 1350 WP_338616594.1 recombinase family protein Machinery gene
  V8H05_RS00195 (V8H05_00195) - 44237..46030 (-) 1794 WP_338616595.1 DUF927 domain-containing protein -
  V8H05_RS00200 (V8H05_00200) - 46030..46326 (-) 297 WP_000273824.1 single-stranded DNA-binding protein -
  V8H05_RS00205 (V8H05_00205) - 46519..47565 (-) 1047 WP_002454338.1 hypothetical protein -
  V8H05_RS00210 (V8H05_00210) - 47837..48908 (-) 1072 Protein_39 IS3 family transposase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52489.15 Da        Isoelectric Point: 9.9328

>NTDB_id=942029 V8H05_RS00190 WP_338616594.1 42654..44003(-) (ccrA) [Staphylococcus aureus strain KWT 2019-23549]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGQLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDGTFINRHPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNLNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLLGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=942029 V8H05_RS00190 WP_338616594.1 42654..44003(-) (ccrA) [Staphylococcus aureus strain KWT 2019-23549]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTACATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGTCTTCAAGAAAAGGCAAAACAAGGTCAATTGATTACAACACATGCGCCTTTTGGTTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATGGTACGTTCATCAATCGACACCCTTATCAAGTTCGTAATATTATCATGA
ATCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCAGATAATCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACTTGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TTTAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterProScan.

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.323

100

0.953
  ccrA Staphylococcus aureus COL

75.278

100

0.753