Detailed information NTG0941245

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: V6K67_RS03050
• Genome accession: NZ_CP145941
• Coordinates: 573876..574775 (+)
• Length: 299 a.a.
• NCBI ID: WP_156703476.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TCI633
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 568876..579775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6K67_RS03030 (V6K67_03030)	trkA	570012..571361 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
V6K67_RS03035 (V6K67_03035)	-	571650..572159 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
V6K67_RS03040 (V6K67_03040)	-	572471..573028 (+)	558	WP_002949523.1	ECF transporter S component	-
V6K67_RS03045 (V6K67_03045)	-	573031..573681 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
V6K67_RS03050 (V6K67_03050)	comR	573876..574775 (+)	900	WP_156703476.1	helix-turn-helix domain-containing protein	Regulator
V6K67_RS03055 (V6K67_03055)	-	575013..576191 (+)	1179	Protein_553	ABC transporter transmembrane domain-containing protein	-
V6K67_RS03060 (V6K67_03060)	-	576477..577045 (+)	569	Protein_554	ATP-binding cassette domain-containing protein	-
V6K67_RS03065 (V6K67_03065)	-	577153..577464 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
V6K67_RS03070 (V6K67_03070)	-	577432..577716 (-)	285	WP_231108755.1	hypothetical protein	-
V6K67_RS03075 (V6K67_03075)	-	577956..578258 (-)	303	WP_011226859.1	hypothetical protein	-
V6K67_RS03080 (V6K67_03080)	-	578482..578853 (-)	372	WP_231108754.1	hypothetical protein	-
V6K67_RS03085 (V6K67_03085)	-	579258..579773 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35345.85 Da
• Isoelectric Point: 5.1073

>NTDB_id=941245 V6K67_RS03050 WP_156703476.1 573876..574775(+) (comR) [Streptococcus thermophilus strain TCI633]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAVENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=941245 V6K67_RS03050 WP_156703476.1 573876..574775(+) (comR) [Streptococcus thermophilus strain TCI633]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGTAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	98.662	100	0.987
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421