Detailed information NTG0940859

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: V6U70_RS07685
• Genome accession: NZ_CP145868
• Coordinates: 1693402..1695642 (-)
• Length: 746 a.a.
• NCBI ID: WP_410532321.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS12
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1688402..1700642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U70_RS07665 (V6U70_07660)	-	1689270..1690130 (-)	861	WP_247915323.1	methionyl aminopeptidase	-
V6U70_RS07670 (V6U70_07665)	spxR	1690170..1691450 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
V6U70_RS07675 (V6U70_07670)	-	1691443..1691988 (-)	546	WP_410532319.1	GNAT family N-acetyltransferase	-
V6U70_RS07680 (V6U70_07675)	-	1692054..1693316 (-)	1263	WP_410532320.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
V6U70_RS07685 (V6U70_07680)	comEC/celB	1693402..1695642 (-)	2241	WP_410532321.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
V6U70_RS07690 (V6U70_07685)	comEA	1695632..1696327 (-)	696	WP_410532322.1	helix-hairpin-helix domain-containing protein	Machinery gene
V6U70_RS07695 (V6U70_07690)	-	1696436..1697191 (-)	756	WP_037599200.1	lysophospholipid acyltransferase family protein	-
V6U70_RS07700 (V6U70_07695)	-	1697322..1698257 (+)	936	WP_175061944.1	polysaccharide deacetylase family protein	-
V6U70_RS07705 (V6U70_07700)	-	1698307..1699071 (+)	765	WP_175061945.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
V6U70_RS07710 (V6U70_07705)	-	1699075..1699344 (+)	270	WP_410532323.1	GIY-YIG nuclease family protein	-
V6U70_RS07715 (V6U70_07710)	-	1699411..1699881 (-)	471	WP_410532324.1	hypothetical protein	-
V6U70_RS07720 (V6U70_07715)	-	1699884..1700396 (-)	513	WP_410532325.1	hypothetical protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84492.38 Da
• Isoelectric Point: 9.8887

>NTDB_id=940859 V6U70_RS07685 WP_410532321.1 1693402..1695642(-) (comEC/celB) [Streptococcus salivarius strain KSS12]
MWLKKAPISLFSLSLLIAALYFTIFITNVYAIGTFVFLMVCFLKHHWKNKTALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRIAQIERLDQVVPQKSLSPLAFFHQLRRRALVHIQTNFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIVLLPFSLCYGLMTGWTVSVLRSLVQSLLAEFGIKKLDNMGITLLLLFLL
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFALSGLLVFSQINPLFEWMEAFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKTLIPYLQARGVSQIDHMVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEVFLDQLHPSLALVSAGENNRYKHPNDETLERFKQRH
IKVLRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=940859 V6U70_RS07685 WP_410532321.1 1693402..1695642(-) (comEC/celB) [Streptococcus salivarius strain KSS12]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTATCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTGATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGACAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CCTTGGTATTAAAAGGAAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAGGTATTTATCGAATCGCTCAGATTGAGCGCTTGGACCAAGTAGTACCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCTTTGGTTCATATCCAGACGAACTTTCCCAGTCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGCCAGCTTTACACAAGTTTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTACGGTCTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATCGTCTTGCTGCCTTTTTCCTTATGTTATGGCCTAATGACAGGATGGACAGTTTCAGTCCTACGTTCCT
TGGTTCAAAGTTTGCTGGCTGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTATTGTTTCTCTTG
TTACCTCATTTTCTCTTAACAGTGGGAGGTGTATTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCACTTAAAAAGTCAATCTGTACAAGCTTAGTGTTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTATTTGATAGTTTTCTCTTACCTGTCTTGACG
GTATTCTTTGCCCTTTCTGGACTGCTAGTCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGGCCTTTTTGACTTG
GATACAATCCTGGATAGGTCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAATTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGTTCAAAGGAAAAATGGCAAGAGGCTAGCCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATATGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGTGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGTACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGCAAGCTACAGGTTCTTTATCCAAATAAAATTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTTTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAGCTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGCTCATCGTCTGAAGTTTTTTTGGATCAGTTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACATTAGAACGTTTTAAGCAACGTCAC
ATTAAGGTTTTACGAACAGATAAAGACGGAGCCATACGTTTTAAGGGTTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-689)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.594	100	0.487
comEC/celB	Streptococcus mitis SK321	48.262	100	0.484
comEC/celB	Streptococcus pneumoniae Rx1	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae D39	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae R6	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae TIGR4	46.586	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.378	99.196	0.43