Detailed information NTG0940620

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V6U67_RS00490
• Genome accession: NZ_CP145865
• Coordinates: 77698..80148 (+)
• Length: 816 a.a.
• NCBI ID: WP_371511101.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS8
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 72698..85148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U67_RS00465 (V6U67_00465)	ahpC	73596..74156 (-)	561	WP_022496765.1	alkyl hydroperoxide reductase subunit C	-
V6U67_RS00470 (V6U67_00470)	rpsB	74429..75196 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
V6U67_RS00475 (V6U67_00475)	tsf	75307..76347 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
V6U67_RS00480 (V6U67_00480)	-	76454..76924 (-)	471	WP_004182164.1	COG2426 family protein	-
V6U67_RS00485 (V6U67_00485)	-	77242..77697 (+)	456	WP_272126820.1	CtsR family transcriptional regulator	-
V6U67_RS00490 (V6U67_00490)	clpC	77698..80148 (+)	2451	WP_371511101.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V6U67_RS00495 (V6U67_00495)	-	80277..81440 (-)	1164	WP_410531190.1	D-alanyl-D-alanine carboxypeptidase	-
V6U67_RS00500 (V6U67_00500)	pbp3	81585..82832 (-)	1248	WP_037603297.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90163.44 Da
• Isoelectric Point: 5.9166

>NTDB_id=940620 V6U67_RS00490 WP_371511101.1 77698..80148(+) (clpC) [Streptococcus salivarius strain KSS8]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDV
IDLRAQSHALEAMLQEAEGIAGVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKITQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=940620 V6U67_RS00490 WP_371511101.1 77698..80148(+) (clpC) [Streptococcus salivarius strain KSS8]
ATGACGACATATTCAAGAAAAATGCAGGCTATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATGTT
ATCGATTTACGTGCACAGTCGCATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTGGTGTGACTGGTGCTGT
AGAGGTAGGTTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAGTCAAAGGCATCAGGGAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAGGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAAACGGCACTTGCGCTTGGCTTGGCACAACGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAAATCATCGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCAGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTACCCGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATAACACAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGATGAAGCAGTTTCAGCCATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCAATTGGTTCCTTTATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAAGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTTGACTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTGTTGGTTTTGGTGCTCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATTATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAACAACTTCGCGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CGTTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGCCAAGTGGTTAGTGGACAA
ACCCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA lid domain (AAA_lid_9) (377-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (109-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.098	100	0.951
clpC	Streptococcus thermophilus LMD-9	94.975	100	0.95
clpC	Streptococcus mutans UA159	73.039	100	0.73
clpC	Streptococcus pneumoniae TIGR4	67.402	100	0.674
clpC	Streptococcus pneumoniae Rx1	67.402	100	0.674
clpC	Streptococcus pneumoniae D39	67.402	100	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.509	100	0.479
clpE	Streptococcus mutans UA159	48.243	76.716	0.37
clpC	Lactococcus lactis subsp. cremoris KW2	44.885	80.27	0.36