Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U66_RS01525 Genome accession   NZ_CP145864
Coordinates   282463..283992 (+) Length   509 a.a.
NCBI ID   WP_002886591.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 277463..288992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS01495 (V6U66_01500) - 277717..277839 (+) 123 Protein_241 energy-coupling factor transporter transmembrane protein EcfT -
  V6U66_RS01500 (V6U66_01505) - 277929..278600 (-) 672 WP_155214076.1 potassium channel family protein -
  V6U66_RS01505 (V6U66_01510) - 278640..280004 (-) 1365 WP_311772411.1 TrkH family potassium uptake protein -
  V6U66_RS01510 (V6U66_01515) rsmG 280073..280786 (-) 714 WP_013990060.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U66_RS01515 (V6U66_01520) - 281085..281621 (+) 537 WP_002886588.1 DUF177 domain-containing protein -
  V6U66_RS01520 (V6U66_01525) covR 281777..282466 (+) 690 WP_002886589.1 response regulator transcription factor Regulator
  V6U66_RS01525 (V6U66_01530) covS 282463..283992 (+) 1530 WP_002886591.1 HAMP domain-containing histidine kinase Regulator
  V6U66_RS01530 (V6U66_01535) nrdR 284114..284593 (+) 480 WP_002886592.1 transcriptional regulator NrdR -
  V6U66_RS01535 (V6U66_01540) - 284590..285765 (+) 1176 WP_049529055.1 DnaD domain protein -
  V6U66_RS01540 (V6U66_01545) dnaI 285769..286671 (+) 903 WP_013990064.1 primosomal protein DnaI -
  V6U66_RS01545 (V6U66_01550) der 286776..288086 (+) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6U66_RS01550 (V6U66_01555) - 288150..288775 (+) 626 Protein_252 HI_0552 family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58137.57 Da        Isoelectric Point: 5.3949

>NTDB_id=940558 V6U66_RS01525 WP_002886591.1 282463..283992(+) (covS) [Streptococcus salivarius strain KSS7]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADRETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940558 V6U66_RS01525 WP_002886591.1 282463..283992(+) (covS) [Streptococcus salivarius strain KSS7]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGATTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGATTCGCCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTTTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTTCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGATTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCGATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCACGTAACC
GTACAACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCAGATCGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986