Detailed information NTG0940484

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V6U65_RS00505
• Genome accession: NZ_CP145863
• Coordinates: 79981..82431 (+)
• Length: 816 a.a.
• NCBI ID: WP_064520679.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS6
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 74981..87431

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS00480 (V6U65_00480)	ahpC	75895..76455 (-)	561	WP_004182174.1	alkyl hydroperoxide reductase subunit C	-
V6U65_RS00485 (V6U65_00485)	rpsB	76728..77495 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
V6U65_RS00490 (V6U65_00490)	tsf	77606..78646 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
V6U65_RS00495 (V6U65_00495)	-	78753..79223 (-)	471	WP_004182164.1	COG2426 family protein	-
V6U65_RS00500 (V6U65_00500)	-	79525..79980 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
V6U65_RS00505 (V6U65_00505)	clpC	79981..82431 (+)	2451	WP_064520679.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V6U65_RS00510 (V6U65_00510)	pbp3	82560..83816 (-)	1257	WP_410532494.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
V6U65_RS00515 (V6U65_00515)	pbp3	83961..85208 (-)	1248	WP_192573926.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90168.48 Da
• Isoelectric Point: 5.8164

>NTDB_id=940484 V6U65_RS00505 WP_064520679.1 79981..82431(+) (clpC) [Streptococcus salivarius strain KSS6]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEAMLQEAEGIAGVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGCIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKITQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQLAALKHLAKDGYDVEMGARPLRRTIQTQVEDRLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=940484 V6U65_RS00505 WP_064520679.1 79981..82431(+) (clpC) [Streptococcus salivarius strain KSS6]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTAGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTGGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTCCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAAGACTTAACGGCAGTAGCCGAATCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTA
GGTGAAGCAGGTGTTGGTAAAACGGCACTTGCGCTTGGCTTGGCACAACGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCAAATATTTTGAAACCTGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACAACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGTCGTTTTGCTAAAATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTACCCGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTTGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATAACACAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGATGAAGCAGTTTCGGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACCGGAAAACGCCCGATTGGTTCCTTTATGTTCCTTGGCCCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTTTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACAGATAGTCGAGGTCGTAAAGTCGACTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACCGTTGGTTTTGGAGCCCAAGACATTTCTCATAATCACCAAG
CTATGCAGTCACGTATTATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTTGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACTAGCTGCCCTTAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCCCGCC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAGGTTATCTGAGCTCTTACTAGGTGGCCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• AAA lid domain (AAA_lid_9) (377-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (109-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	94.853	100	0.949
clpC	Streptococcus thermophilus LMD-9	94.73	100	0.947
clpC	Streptococcus mutans UA159	72.794	100	0.728
clpC	Streptococcus pneumoniae TIGR4	67.279	100	0.673
clpC	Streptococcus pneumoniae Rx1	67.279	100	0.673
clpC	Streptococcus pneumoniae D39	67.279	100	0.673
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.301	100	0.512
clpC	Bacillus subtilis subsp. subtilis str. 168	47.509	100	0.479
clpE	Streptococcus mutans UA159	48.243	76.716	0.37
clpC	Lactococcus lactis subsp. cremoris KW2	44.885	80.27	0.36