Detailed information NTG0940418

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: V6U64_RS00800
• Genome accession: NZ_CP145862
• Coordinates: 154490..155590 (+)
• Length: 366 a.a.
• NCBI ID: WP_148263031.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 149490..160590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U64_RS00790 (V6U64_00790)	-	153225..153587 (+)	363	WP_014635121.1	DUF1033 family protein	-
V6U64_RS00795 (V6U64_00795)	comGA/cglA/cilD	153667..154608 (+)	942	WP_002887018.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U64_RS00800 (V6U64_00800)	comYB	154490..155590 (+)	1101	WP_148263031.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U64_RS00805 (V6U64_00805)	comYC	155599..155913 (+)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U64_RS00810 (V6U64_00810)	comYD	155873..156301 (+)	429	WP_270334813.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U64_RS00815 (V6U64_00815)	comGE	156333..156563 (+)	231	WP_021144685.1	competence type IV pilus minor pilin ComGE	-
V6U64_RS00820 (V6U64_00820)	comYF	156550..156987 (+)	438	WP_227071977.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U64_RS00825 (V6U64_00825)	comGG	156965..157282 (+)	318	WP_227071976.1	competence type IV pilus minor pilin ComGG	-
V6U64_RS00830 (V6U64_00830)	comYH	157327..158283 (+)	957	WP_227071975.1	class I SAM-dependent methyltransferase	Machinery gene
V6U64_RS00835 (V6U64_00835)	-	158340..159533 (+)	1194	WP_002885831.1	acetate kinase	-
V6U64_RS00840 (V6U64_00840)	-	159786..159983 (+)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41650.75 Da
• Isoelectric Point: 10.1478

>NTDB_id=940418 V6U64_RS00800 WP_148263031.1 154490..155590(+) (comYB) [Streptococcus salivarius strain KSS4]
MPVKISKATRQPAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGTDLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=940418 V6U64_RS00800 WP_148263031.1 154490..155590(+) (comYB) [Streptococcus salivarius strain KSS4]
TTGCCAGTGAAAATTTCCAAAGCCACTCGTCAACCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCCTTGTCTCTTATG
AAAGCGAGTTTAATGCGAGGCGACAGGTTGGACCAGATGTTTGCGTCAGTAGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTATCCTATTCTACTTCTGGGGTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAATTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTGCTTGTATTAAGCTTAATTCTCTATCTATGGGTGAAACGCCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGAGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTGGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGACTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	55.102	93.716	0.516
comYB	Streptococcus mutans UA159	55.102	93.716	0.516
comYB	Streptococcus gordonii str. Challis substr. CH1	51.603	93.716	0.484
comGB/cglB	Streptococcus mitis NCTC 12261	50.147	92.623	0.464
comGB/cglB	Streptococcus mitis SK321	49.408	92.35	0.456
comGB/cglB	Streptococcus pneumoniae Rx1	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae D39	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae R6	49.112	92.35	0.454
comGB/cglB	Streptococcus pneumoniae TIGR4	49.112	92.35	0.454
comGB	Lactococcus lactis subsp. cremoris KW2	44.681	89.891	0.402