Detailed information NTG0940350

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: V6U63_RS00535
• Genome accession: NZ_CP145861
• Coordinates: 85107..87557 (+)
• Length: 816 a.a.
• NCBI ID: WP_410535127.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS3
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 80107..92557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U63_RS00510 (V6U63_00510)	ahpC	81003..81563 (-)	561	WP_064520680.1	alkyl hydroperoxide reductase subunit C	-
V6U63_RS00515 (V6U63_00515)	rpsB	81836..82603 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
V6U63_RS00520 (V6U63_00520)	tsf	82714..83754 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
V6U63_RS00525 (V6U63_00525)	-	83863..84333 (-)	471	WP_004182164.1	COG2426 family protein	-
V6U63_RS00530 (V6U63_00530)	-	84651..85106 (+)	456	WP_014633783.1	CtsR family transcriptional regulator	-
V6U63_RS00535 (V6U63_00535)	clpC	85107..87557 (+)	2451	WP_410535127.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V6U63_RS00540 (V6U63_00540)	pbp3	87685..88941 (-)	1257	WP_022496763.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
V6U63_RS00545 (V6U63_00545)	pbp3	89086..90333 (-)	1248	WP_410535129.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90207.56 Da
• Isoelectric Point: 6.0145

>NTDB_id=940350 V6U63_RS00535 WP_410535127.1 85107..87557(+) (clpC) [Streptococcus salivarius strain KSS3]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALGAMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKAIQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDRLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=940350 V6U63_RS00535 WP_410535127.1 85107..87557(+) (clpC) [Streptococcus salivarius strain KSS3]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGGGGCTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTAACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTTCTCCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCACGACCTTCGTAAGCCTAAAAAGTCAAAGGCATCAGGTAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTACACAAAAGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAATTGCATACGATTATCGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCGAATATTTTGAAACCTGCTCTAGCACGTGGAACCCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAAAAAGATGCAGCTCTTTCTCGTCGTTTTGCTAAAATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCAGTTGAGACAGCGGTCAAGGCGGCCCACCGTTATTTGACGAGTAAAAACTTACCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CACTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTATCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGATGAAGCAGTTTCAGCCATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTTGACTTTTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTGTTGGTTTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATTATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTTGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGGTGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCCCTTAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCCCGCC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAGGTTATCTGAGCTCTTACTAGGTGGCCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• AAA lid domain (AAA_lid_9) (377-455)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.221	100	0.952
clpC	Streptococcus thermophilus LMD-9	95.098	100	0.951
clpC	Streptococcus mutans UA159	72.917	100	0.729
clpC	Streptococcus pneumoniae TIGR4	67.402	100	0.674
clpC	Streptococcus pneumoniae Rx1	67.402	100	0.674
clpC	Streptococcus pneumoniae D39	67.402	100	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.344	100	0.507
clpC	Bacillus subtilis subsp. subtilis str. 168	46.659	100	0.471
clpE	Streptococcus mutans UA159	48.243	76.716	0.37