Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6U62_RS08525 Genome accession   NZ_CP145860
Coordinates   1857501..1859030 (-) Length   509 a.a.
NCBI ID   WP_002883784.1    Uniprot ID   A0A1V0GG48
Organism   Streptococcus salivarius strain KSS2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1852501..1864030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U62_RS08500 (V6U62_08480) - 1852713..1853342 (-) 630 WP_022495832.1 hypothetical protein -
  V6U62_RS08505 (V6U62_08485) der 1853407..1854717 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6U62_RS08510 (V6U62_08490) dnaI 1854822..1855724 (-) 903 WP_002883792.1 primosomal protein DnaI -
  V6U62_RS08515 (V6U62_08495) - 1855728..1856903 (-) 1176 WP_129852167.1 DnaD domain protein -
  V6U62_RS08520 (V6U62_08500) nrdR 1856900..1857379 (-) 480 WP_073689471.1 transcriptional regulator NrdR -
  V6U62_RS08525 (V6U62_08505) covS 1857501..1859030 (-) 1530 WP_002883784.1 HAMP domain-containing histidine kinase Regulator
  V6U62_RS08530 (V6U62_08510) covR 1859027..1859716 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6U62_RS08535 (V6U62_08515) - 1859872..1860408 (-) 537 WP_002883813.1 DUF177 domain-containing protein -
  V6U62_RS08540 (V6U62_08520) rsmG 1860707..1861420 (+) 714 WP_349955348.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6U62_RS08545 (V6U62_08525) - 1861489..1862853 (+) 1365 WP_022496218.1 TrkH family potassium uptake protein -
  V6U62_RS08550 (V6U62_08530) - 1862893..1863564 (+) 672 WP_022496217.1 potassium channel family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58071.44 Da        Isoelectric Point: 5.1853

>NTDB_id=940332 V6U62_RS08525 WP_002883784.1 1857501..1859030(-) (covS) [Streptococcus salivarius strain KSS2]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940332 V6U62_RS08525 WP_002883784.1 1857501..1859030(-) (covS) [Streptococcus salivarius strain KSS2]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGAGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAAGTAAATAAACTGAAGTCAGTATCCTATAAAGGGAAGCGTGGTTTC
CTGCTACAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTCGAAGTGGGAATGACGGTCCTAGTTATTGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGGAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTACAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACACAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGTTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GG48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

100

100

1