Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   V6T26_RS08650 Genome accession   NZ_CP145858
Coordinates   1869221..1870750 (-) Length   509 a.a.
NCBI ID   WP_175062728.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS11     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1864221..1875750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6T26_RS08625 (V6T26_08615) - 1864434..1865063 (-) 630 WP_410541226.1 HI_0552 family protein -
  V6T26_RS08630 (V6T26_08620) der 1865127..1866437 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  V6T26_RS08635 (V6T26_08625) dnaI 1866542..1867444 (-) 903 WP_002883792.1 primosomal protein DnaI -
  V6T26_RS08640 (V6T26_08630) - 1867448..1868623 (-) 1176 WP_129852167.1 DnaD domain protein -
  V6T26_RS08645 (V6T26_08635) nrdR 1868620..1869099 (-) 480 WP_002883820.1 transcriptional regulator NrdR -
  V6T26_RS08650 (V6T26_08640) covS 1869221..1870750 (-) 1530 WP_175062728.1 HAMP domain-containing histidine kinase Regulator
  V6T26_RS08655 (V6T26_08645) covR 1870747..1871436 (-) 690 WP_002883757.1 response regulator transcription factor Regulator
  V6T26_RS08660 (V6T26_08650) - 1871593..1872129 (-) 537 WP_175062727.1 DUF177 domain-containing protein -
  V6T26_RS08665 (V6T26_08655) rsmG 1872429..1873142 (+) 714 WP_175062726.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  V6T26_RS08670 (V6T26_08660) - 1873211..1874575 (+) 1365 WP_410541227.1 TrkH family potassium uptake protein -
  V6T26_RS08675 (V6T26_08665) - 1874615..1875286 (+) 672 WP_073949300.1 potassium channel family protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58013.40 Da        Isoelectric Point: 5.2781

>NTDB_id=940266 V6T26_RS08650 WP_175062728.1 1869221..1870750(-) (covS) [Streptococcus salivarius strain KSS11]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNTTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDAMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=940266 V6T26_RS08650 WP_175062728.1 1869221..1870750(-) (covS) [Streptococcus salivarius strain KSS11]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCAGCCAATACGCTACTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCTCAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCCGACGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCGATCATTAATGGAGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
GGTTGCGATTTCTAATAAATTATATTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAGAACACAGATTCGCCTCCAGGTATGTCCGAAGTAAATAAACTGAAGTCAGTATCCTATAAAGGGAAGCGTGGTTTC
CTGCTGCAAGTTCCAATCTACGGTAAAGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGATTTTCTTATTGATTTTCCTCGAAGTGGGAATGACGGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACACCGATTGCGGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGGAAAAATGACCCTGAAATCCTTGAGGAAAGTCTTGAGGCTGCAAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCACAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGTGTCTTGCATGAAGATTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCAGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGCAATGTTGGTACAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAATC
GTACAACAACACAATCTGGTGTTGGTATTGGTTTGTCAATTCTTTACCAAATTGTGGAAGCTTATCGTTGCCGTATCGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.804

100

0.998