Detailed information NTG0940256

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: V6T26_RS07135
• Genome accession: NZ_CP145858
• Coordinates: 1549271..1551541 (+)
• Length: 756 a.a.
• NCBI ID: WP_201042702.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS11
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1544271..1556541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6T26_RS07110 (V6T26_07110)	-	1545372..1545848 (-)	477	WP_064523218.1	ferrous iron transport protein A	-
V6T26_RS07115 (V6T26_07115)	-	1546020..1546754 (-)	735	WP_073686440.1	amino acid ABC transporter ATP-binding protein	-
V6T26_RS07120 (V6T26_07120)	-	1546754..1547434 (-)	681	WP_002890385.1	amino acid ABC transporter permease	-
V6T26_RS07125 (V6T26_07125)	-	1547749..1547979 (-)	231	WP_002885970.1	DUF1797 family protein	-
V6T26_RS07130 (V6T26_07130)	argF	1548048..1549028 (-)	981	WP_201042704.1	ornithine carbamoyltransferase	-
V6T26_RS07135 (V6T26_07135)	clpE	1549271..1551541 (+)	2271	WP_201042702.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
V6T26_RS07140 (V6T26_07140)	-	1551684..1552142 (+)	459	WP_002890379.1	NUDIX hydrolase	-
V6T26_RS07145 (V6T26_07145)	-	1552152..1552454 (+)	303	WP_002885967.1	DUF1827 family protein	-
V6T26_RS07150 (V6T26_07150)	-	1552500..1553462 (-)	963	WP_410541154.1	Gfo/Idh/MocA family protein	-
V6T26_RS07155 (V6T26_07155)	-	1553562..1554797 (-)	1236	WP_198463285.1	aminoacyltransferase	-
V6T26_RS07160 (V6T26_07160)	-	1554775..1555458 (-)	684	WP_410541155.1	TVP38/TMEM64 family protein	-
V6T26_RS07165 (V6T26_07165)	-	1555541..1556161 (-)	621	WP_037602103.1	DUF3862 domain-containing protein	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83978.03 Da
• Isoelectric Point: 4.9707

>NTDB_id=940256 V6T26_RS07135 WP_201042702.1 1549271..1551541(+) (clpE) [Streptococcus salivarius strain KSS11]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGDNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGATRENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQCLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKATQKAEAAKESD

Nucleotide

• Length: 2271 bp

>NTDB_id=940256 V6T26_RS07135 WP_201042702.1 1549271..1551541(+) (clpE) [Streptococcus salivarius strain KSS11]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTTAATCAATTCAATCAAACTGGAGGTTCCA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGTGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGACAATACACAAGGGCCAGGCCGCCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATCGATCCAGTCATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAATCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTCGTTGAAGGACTAGCTCAAAAAATTGTAGATGGTAGCGTTCCTCAAAAACTCCAAGGCAAACA
AGTTATCCGTCTTGATGTGGTCAGCTTGGTTCAAGGGACTGGTATCCGAGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGACGAAATTCATGAAATCGTAGGAGCTGGTAATGCTGGA
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCCCTTGCTCGTGGGGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAATACCGCATCATCGAAAAAGATGCTGCCCTTGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACTGTTG
AGGAAACCATCACTATTTTGCGTGGGATTCAGCCTAAATATCAAGACTACCACCACGTCAAATATACGGACGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGCTTCTTGCCAGACAAGGCCATCGACCTTCTGGATGAAGC
TGGTTCGAAGATGAACTTGACCCTCAACTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAGGACTTTGAAAAGGCTGCCTATTTCCGTGACCAAATTGCCAAATACAAGGAAATGCAA
AAGCAAACCATCAAAGACCAGGATATGCCTGTCATCACCGAAAAACATATCGAAGCTATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCCGATGATCTTAAATCACATGTTATCGGAC
AAGATGCTGCAGTTGATAAGATTGCTAAAGCTATCCGCCGTAATCGTGTTGGATTGGGTGCTCCAAACCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTTGGTGCCCCCCCAGGAT
ATGTTGGTTACGACGAAGCTGGTCAGTTGACTGAAAAAGTCCGCCGTAATCCTTATTCACTTATTCTTTTAGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTACTTGACGACGGTCGTTTGACTGATGGTCAAGGGCGCAC
TGTAAGCTTCAAGGATACCATCATCATCATGACATCAAATGCTGGTACTGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTACTCGTGAAAATCGTACCAATTCTGTTCTTAACCAACTTGGAGATTTCTTCAGTCCTGAATTTATGAACCGCTTTGAC
GGTATTATCGAATTCTCTGCCCTTAGCAAAGAAAATCTCCTTACTATCGTGGACCTCATGCTTGATAATGTCAACCAATG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACTGAGAAAGTTAAGGAAAAATTGGTTGATCTTGGTTACGATCCTAAGA
TGGGTGCTCGACCACTACGTCGTACTATCCAAGATCACATTGAAGATGCTATTACCGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGCCACATTACCATTAAGTCTGCTAAAAAAGCCGAAAAAGCTACTCA
AAAAGCTGAGGCAGCAAAAGAATCTGATTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (477-640)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (648-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (154-274)

• AAA lid domain (AAA_lid_9) (292-390)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.505	99.471	0.851
clpE	Streptococcus pneumoniae Rx1	82.869	99.603	0.825
clpE	Streptococcus pneumoniae D39	82.869	99.603	0.825
clpE	Streptococcus pneumoniae R6	82.869	99.603	0.825
clpE	Streptococcus pneumoniae TIGR4	82.869	99.603	0.825
clpC	Lactococcus lactis subsp. cremoris KW2	78.718	96.958	0.763
clpC	Bacillus subtilis subsp. subtilis str. 168	51.698	85.714	0.443
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	44.22	91.534	0.405
clpC	Streptococcus pneumoniae Rx1	47.36	82.672	0.392
clpC	Streptococcus pneumoniae D39	47.36	82.672	0.392
clpC	Streptococcus pneumoniae TIGR4	47.2	82.672	0.39
clpC	Streptococcus thermophilus LMD-9	47.04	82.672	0.389
clpC	Streptococcus thermophilus LMG 18311	46.72	82.672	0.386
clpC	Streptococcus mutans UA159	46.228	82.407	0.381