Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   V6667_RS06225 Genome accession   NZ_CP145811
Coordinates   1366237..1368462 (-) Length   741 a.a.
NCBI ID   WP_274584918.1    Uniprot ID   A0A9X4IAU1
Organism   Neisseria leonii strain CCUG 45853     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1361237..1373462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6667_RS06215 (V6667_06215) - 1362112..1364343 (-) 2232 WP_338809041.1 type I secretion system permease/ATPase -
  V6667_RS06220 (V6667_06220) - 1364350..1366047 (-) 1698 WP_338809042.1 TolC family protein -
  V6667_RS06225 (V6667_06225) comA 1366237..1368462 (-) 2226 WP_274584918.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V6667_RS06230 (V6667_06230) bfr 1368579..1369052 (-) 474 WP_338809737.1 bacterioferritin -
  V6667_RS06235 (V6667_06235) bfr 1369079..1369543 (-) 465 WP_274572144.1 bacterioferritin -
  V6667_RS06240 (V6667_06240) typA 1369974..1371782 (+) 1809 WP_338809043.1 translational GTPase TypA -
  V6667_RS06245 (V6667_06245) - 1372063..1372647 (+) 585 WP_274570986.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 741 a.a.        Molecular weight: 80436.53 Da        Isoelectric Point: 10.2971

>NTDB_id=940019 V6667_RS06225 WP_274584918.1 1366237..1368462(-) (comA) [Neisseria leonii strain CCUG 45853]
MRRYLAAWPTGVLLSFGLADIPPLWLWTAAAVLLLSAALRFRRLRPLPVLLAGAAFAVWQVQTALDGQWPAERQGREVLL
VRVADLPQTDGRRTVFAADAWTEDKRYYRLRLSDYEGRDWPAGSYWRVSARLRPPVGEVNLRGFNREAWALANGLAGIGS
VGAARTAVDAEKRPFSDGLAAVRTAISLRWQRWYGQGADNGVALMRALSVGEQGALSDEMWQVLRPLGLNHLVSISGLHV
SMVALLAAVFGRVLLKYGPHTPKRPRLWLLTVGLAAAWAYAALAGFAVPTVRAAAMLTVVALAWARGGTASAWTAWWAAL
AGVLTLWPTAVLAAGTWLSFGLVGALLWGGSWRTGEQGGGLWRAQWAAGMMSAVMLGYGFAVLPLWSPAVNLPAIPWFSW
VLVPLALAASAIPWPPLQQAAVWLGEYTWRALAWLAEYAPEWSVAAAPWPLAAAAFCAVAVWLVPAGLGLRPWAAAVLLL
FVLYRPERPPSGRLNVTVLDSGQGLAVWLQTANRDLLFDTGTAAAAGGQVIPALRAAGVRRLDTLVFSHRDNDHDGGGQM
VRQAFAPDRVWAGQPEFYSGARHCSPASWQWDGVHFEWLTPEESADSDNGKSCVLRAVAGGEAVLLTGDLDSRGEQRLIA
QYGSALFSQLLILGHHGSNTSSAGRFLNLVSPEYAVASSGYANAYGHPSPAVQNRVRAHGGRLLRTDLSGAWRFELGTGQ
RLPVQVRPWRPYWQKKPFDWV

Nucleotide


Download         Length: 2226 bp        

>NTDB_id=940019 V6667_RS06225 WP_274584918.1 1366237..1368462(-) (comA) [Neisseria leonii strain CCUG 45853]
ATGCGGCGGTATCTGGCGGCGTGGCCGACGGGGGTGTTGTTGTCGTTCGGTTTGGCGGACATACCGCCGCTTTGGCTGTG
GACGGCCGCCGCCGTGTTGCTGCTGTCTGCCGCTTTGCGCTTCCGCCGCCTGAGGCCGCTGCCCGTTTTGCTGGCCGGAG
CGGCGTTTGCGGTGTGGCAGGTTCAGACGGCCTTGGACGGGCAATGGCCGGCGGAGCGGCAAGGGCGGGAAGTGTTGCTG
GTGCGGGTGGCGGACTTGCCGCAAACCGACGGGCGGCGGACGGTGTTTGCCGCCGACGCGTGGACGGAGGACAAGCGGTA
TTACCGTCTGCGCTTGTCGGATTATGAGGGGCGCGACTGGCCGGCGGGCAGCTATTGGCGGGTATCGGCGCGTTTGCGCC
CGCCGGTGGGCGAAGTGAATTTGCGCGGTTTCAACCGCGAGGCATGGGCGTTGGCCAACGGTTTGGCCGGTATCGGCAGC
GTGGGCGCGGCGCGGACGGCGGTTGATGCGGAAAAACGGCCGTTTTCAGACGGCCTGGCGGCCGTGAGGACGGCGATCAG
TCTGCGCTGGCAGCGTTGGTACGGGCAGGGCGCGGATAACGGGGTGGCGCTGATGCGGGCGTTGAGTGTGGGCGAGCAGG
GGGCGTTGTCCGACGAAATGTGGCAGGTACTGCGCCCGCTGGGGCTGAATCATTTGGTGAGTATTTCGGGGCTGCATGTA
TCGATGGTGGCTCTGCTGGCCGCCGTATTCGGGCGGGTGCTGCTGAAATATGGGCCGCATACGCCCAAACGGCCGCGTCT
GTGGCTGTTGACTGTCGGTTTGGCGGCAGCATGGGCGTATGCGGCGTTGGCCGGTTTTGCCGTACCGACGGTACGTGCGG
CGGCGATGCTGACGGTGGTGGCGCTGGCATGGGCGCGGGGCGGAACGGCATCGGCGTGGACGGCTTGGTGGGCGGCGTTG
GCGGGGGTGCTGACGCTGTGGCCGACGGCAGTTCTGGCGGCGGGGACATGGTTGTCTTTCGGTTTGGTGGGTGCTTTGCT
GTGGGGCGGCAGTTGGCGCACGGGTGAGCAGGGAGGCGGGCTTTGGCGGGCGCAATGGGCGGCAGGTATGATGTCGGCAG
TGATGTTGGGCTACGGATTTGCGGTGCTGCCGTTATGGAGTCCGGCGGTCAATCTGCCCGCGATACCGTGGTTTTCATGG
GTGTTGGTGCCTTTGGCACTGGCCGCTTCGGCAATACCGTGGCCGCCGCTGCAACAGGCGGCGGTTTGGTTGGGCGAATA
CACTTGGCGCGCACTGGCATGGCTGGCCGAGTATGCGCCCGAGTGGTCGGTAGCTGCCGCGCCTTGGCCGCTGGCTGCGG
CCGCATTTTGTGCCGTGGCGGTATGGCTGGTACCGGCGGGCTTGGGTTTGCGCCCGTGGGCGGCGGCGGTTTTGCTGCTG
TTTGTGCTGTACCGGCCGGAGCGGCCGCCGTCAGGCCGTCTGAATGTAACGGTGCTGGACAGCGGGCAGGGGTTGGCGGT
ATGGCTGCAAACGGCCAATCGGGATTTATTGTTCGATACGGGAACGGCCGCCGCTGCCGGCGGTCAGGTCATACCGGCAT
TGCGCGCGGCCGGTGTGCGGCGTTTGGACACGCTGGTATTCTCGCACCGGGATAACGATCACGACGGCGGCGGGCAGATG
GTGCGGCAGGCATTTGCGCCCGATAGAGTGTGGGCGGGGCAGCCGGAGTTTTACAGCGGGGCACGGCACTGTTCGCCTGC
ATCGTGGCAGTGGGACGGTGTCCATTTCGAGTGGCTGACACCGGAGGAGTCGGCCGACAGCGATAACGGGAAGAGCTGTG
TGCTGCGGGCGGTGGCCGGCGGGGAGGCGGTGCTGCTGACCGGCGATTTGGACAGTCGGGGCGAGCAGCGGCTGATAGCG
CAATACGGCTCCGCGCTGTTCAGCCAGCTGCTGATTTTGGGACACCACGGCAGCAACACATCGTCTGCGGGCCGTTTTTT
GAATCTGGTGTCGCCCGAATATGCCGTTGCGTCCAGCGGTTATGCCAATGCCTACGGTCACCCGTCGCCTGCCGTGCAGA
ACCGTGTGCGCGCCCACGGCGGCCGTCTGCTGCGTACCGATTTGTCCGGTGCATGGCGGTTCGAACTGGGGACGGGGCAG
CGTTTGCCCGTCCAAGTGCGGCCGTGGCGGCCGTATTGGCAGAAAAAGCCGTTTGATTGGGTATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-163)

Metallo-beta-lactamase superfamily (Lactamase_B)

(502-678)

Competence protein (Competence)

(208-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

55.87

100

0.559