Detailed information NTG0938925

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V5F87_RS04370
• Genome accession: NZ_CP145595
• Coordinates: 925415..926461 (+)
• Length: 348 a.a.
• NCBI ID: WP_002435929.1
• Uniprot ID: A0A0S4MEI3
• Organism: Staphylococcus capitis strain kcgeb_sa
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 920415..931461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5F87_RS04340 (V5F87_04340)	-	920679..921404 (+)	726	WP_002469718.1	type 1 glutamine amidotransferase	-
V5F87_RS04345 (V5F87_04345)	-	921633..922175 (+)	543	WP_023350030.1	hypothetical protein	-
V5F87_RS04350 (V5F87_04350)	-	922253..923242 (-)	990	WP_002435886.1	aromatic acid exporter family protein	-
V5F87_RS04355 (V5F87_04355)	map	923416..924171 (+)	756	WP_002435911.1	type I methionyl aminopeptidase	-
V5F87_RS04360 (V5F87_04360)	-	924316..924702 (+)	387	WP_002453601.1	hypothetical protein	-
V5F87_RS04365 (V5F87_04365)	liaF	924717..925418 (+)	702	WP_002435891.1	cell wall-active antibiotics response protein LiaF	-
V5F87_RS04370 (V5F87_04370)	vraS	925415..926461 (+)	1047	WP_002435929.1	sensor histidine kinase	Regulator
V5F87_RS04375 (V5F87_04375)	vraR	926451..927080 (+)	630	WP_002469716.1	two-component system response regulator VraR	Regulator
V5F87_RS04380 (V5F87_04380)	-	927145..928398 (-)	1254	WP_002435884.1	YihY/virulence factor BrkB family protein	-
V5F87_RS04385 (V5F87_04385)	-	928735..929019 (-)	285	WP_002435890.1	hypothetical protein	-
V5F87_RS04390 (V5F87_04390)	-	929026..929490 (-)	465	WP_002435947.1	low molecular weight protein-tyrosine-phosphatase	-
V5F87_RS04395 (V5F87_04395)	-	929631..929837 (+)	207	WP_002435959.1	DUF1128 domain-containing protein	-
V5F87_RS04400 (V5F87_04400)	-	929851..931092 (+)	1242	WP_023350031.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40136.57 Da
• Isoelectric Point: 6.0600

>NTDB_id=938925 V5F87_RS04370 WP_002435929.1 925415..926461(+) (vraS) [Staphylococcus capitis strain kcgeb_sa]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNILIILLCIIVGSVLAYKINQQNDWLKS
QIERSIEGETVGINDQNLELYSETLEIYHTLVPLNQELHRLRMKTQNMTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNKEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDESNGD

Nucleotide

• Length: 1047 bp

>NTDB_id=938925 V5F87_RS04370 WP_002435929.1 925415..926461(+) (vraS) [Staphylococcus capitis strain kcgeb_sa]
ATGAATCACTACTTGAGAGCAATTGGTTCAATGCTAATACTTGTATATAGCATGCTAACTGCTTTTTTATTCATTGATAA
GGTGTTCGTCAATATTATTTATTTTCAAGGGATGTTTTACACCCAAATTTTTGGAATACCAGTATTTTTATTCCTAAATA
TATTAATCATCTTACTATGTATTATCGTTGGCTCTGTGTTAGCGTATAAAATCAATCAACAAAATGATTGGCTTAAGTCA
CAAATTGAAAGGTCTATTGAAGGTGAAACAGTAGGCATAAATGATCAAAACCTAGAGTTATACAGTGAAACGTTAGAAAT
TTACCATACTTTAGTTCCTTTAAATCAAGAATTACACCGATTGAGAATGAAAACGCAGAATATGACCAATGAAAATTATA
ATATGAATGATGTAAAAGTGAAGAAAATTATTGAAGACGAACGTCAACGTTTAGCAAGAGAACTACATGACTCAGTTAGT
CAGCAACTATTTGCAGCAAGTATGATGTTGTCAGCGATTAAAGAGTCAAAATTAGAACCACCTTTAGACCAACAAATACC
TGTACTAGAGAAGATGGTTCAAGACTCTCAGCTCGAAATGAGAGCATTATTATTACATCTAAGACCTATTGGTTTGAAAG
ACAAATCATTAGGAGAGGGTATTAAAGATTTAGTCATTGATCTTCAAAAGAAAGTCCCTATGAAAGTTGTTCATGAAATT
CAAGATTTCAAAGTACCAAAAGGGATAGAAGATCATTTGTTTAGAATCACCCAAGAGGCTATTTCTAATACATTACGACA
CTCTAATGGTTCTAAGGTAACAGTTGAATTATTTAATAAAGAAGATTATTTACTACTTAGAATTCAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTTGAACAGAGTTATGGATTAAAAAATATGAGAGAACGTGCTTTAGAGATTGGTGCCACA
TTCCATATCGTATCGTTACCGGATTCAGGTACGAGAATAGAAGTTAAAGCACCATTGAATAAGGAGGATGAATCAAATGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0S4MEI3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.586	98.563	0.922