Detailed information NTG0938525

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: ACEWY3_RS10335
• Genome accession: NZ_CP169265
• Coordinates: 2077154..2078236 (-)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain CBC226
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2072154..2083236

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACEWY3_RS10315 (ACEWY3_10315)	-	2072763..2072867 (-)	105	WP_001790092.1	hypothetical protein	-
ACEWY3_RS10320 (ACEWY3_10320)	secA	2072909..2075440 (-)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
ACEWY3_RS10325 (ACEWY3_10325)	hpf	2075854..2076426 (-)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
ACEWY3_RS10330 (ACEWY3_10330)	-	2076487..2077161 (-)	675	WP_001057965.1	ComF family protein	-
ACEWY3_RS10335 (ACEWY3_10335)	comFA	2077154..2078236 (-)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
ACEWY3_RS10340 (ACEWY3_10340)	fakB1	2078600..2079466 (-)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
ACEWY3_RS10345 (ACEWY3_10345)	-	2079610..2080251 (+)	642	WP_374150578.1	YigZ family protein	-
ACEWY3_RS10350 (ACEWY3_10350)	-	2080421..2081476 (-)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
ACEWY3_RS10355 (ACEWY3_10355)	gdpS	2081794..2082864 (+)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=938525 ACEWY3_RS10335 WP_001548033.1 2077154..2078236(-) (comFA) [Staphylococcus aureus strain CBC226]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=938525 ACEWY3_RS10335 WP_001548033.1 2077154..2078236(-) (comFA) [Staphylococcus aureus strain CBC226]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367