Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | V6C94_RS00445 | Genome accession | NZ_CP145253 |
| Coordinates | 90946..92574 (-) | Length | 542 a.a. |
| NCBI ID | WP_023350828.1 | Uniprot ID | T1T072 |
| Organism | Staphylococcus capitis subsp. urealyticus strain Sc1191106 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 37576..93944 | 90946..92574 | within | 0 |
Gene organization within MGE regions
Location: 37576..93944
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V6C94_RS00160 (V6C94_00160) | - | 37576..39252 (+) | 1677 | WP_367122003.1 | recombinase family protein | - |
| V6C94_RS00165 (V6C94_00165) | - | 39358..39696 (+) | 339 | WP_000171559.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C94_RS00170 (V6C94_00170) | - | 39792..40103 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| V6C94_RS00175 (V6C94_00175) | - | 40119..40625 (+) | 507 | WP_000447786.1 | DUF1643 domain-containing protein | - |
| V6C94_RS00180 (V6C94_00180) | - | 40774..41448 (-) | 675 | WP_001106056.1 | IS6-like element IS257 family transposase | - |
| V6C94_RS00185 (V6C94_00185) | - | 41532..41873 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| V6C94_RS00190 (V6C94_00190) | - | 42790..43533 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| V6C94_RS00195 (V6C94_00195) | - | 43630..44058 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| V6C94_RS00200 (V6C94_00200) | mecA | 44104..46113 (-) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| V6C94_RS00205 (V6C94_00205) | - | 46210..46317 (+) | 108 | Protein_38 | beta-lactam sensor/signal transducer MecR1 | - |
| V6C94_RS00210 (V6C94_00210) | - | 46358..47032 (+) | 675 | Protein_39 | IS6 family transposase | - |
| V6C94_RS00215 (V6C94_00215) | - | 47092..47520 (-) | 429 | WP_000671996.1 | VOC family protein | - |
| V6C94_RS00220 (V6C94_00220) | - | 47601..48530 (+) | 930 | WP_000750311.1 | HTH domain-containing protein | - |
| V6C94_RS00225 (V6C94_00225) | - | 48692..50680 (+) | 1989 | WP_001038847.1 | hypothetical protein | - |
| V6C94_RS00230 (V6C94_00230) | - | 50875..51984 (+) | 1110 | WP_000283873.1 | DNA polymerase | - |
| V6C94_RS00235 (V6C94_00235) | - | 51977..52345 (+) | 369 | WP_001058155.1 | hypothetical protein | - |
| V6C94_RS00240 (V6C94_00240) | - | 52345..53961 (+) | 1617 | WP_001015575.1 | DUF5906 domain-containing protein | - |
| V6C94_RS00245 (V6C94_00245) | - | 54186..55862 (+) | 1677 | WP_367122003.1 | recombinase family protein | - |
| V6C94_RS00250 (V6C94_00250) | - | 55968..56306 (+) | 339 | WP_000171559.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C94_RS00255 (V6C94_00255) | - | 56402..56713 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| V6C94_RS00260 (V6C94_00260) | - | 56729..57235 (+) | 507 | WP_000447786.1 | DUF1643 domain-containing protein | - |
| V6C94_RS00265 (V6C94_00265) | - | 57384..58058 (-) | 675 | WP_001106056.1 | IS6-like element IS257 family transposase | - |
| V6C94_RS00270 (V6C94_00270) | - | 58142..58483 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| V6C94_RS00275 (V6C94_00275) | - | 59400..60143 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| V6C94_RS00280 (V6C94_00280) | - | 60240..60668 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| V6C94_RS00285 (V6C94_00285) | mecA | 60714..62723 (-) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| V6C94_RS00290 (V6C94_00290) | - | 62820..62927 (+) | 108 | Protein_55 | beta-lactam sensor/signal transducer MecR1 | - |
| V6C94_RS00295 (V6C94_00295) | - | 62968..63642 (+) | 675 | Protein_56 | IS6 family transposase | - |
| V6C94_RS00300 (V6C94_00300) | - | 63702..64130 (-) | 429 | WP_000671996.1 | VOC family protein | - |
| V6C94_RS00305 (V6C94_00305) | - | 64211..65140 (+) | 930 | WP_000750311.1 | HTH domain-containing protein | - |
| V6C94_RS00310 (V6C94_00310) | - | 65302..67290 (+) | 1989 | WP_001038847.1 | hypothetical protein | - |
| V6C94_RS00315 (V6C94_00315) | - | 67485..68594 (+) | 1110 | WP_000283873.1 | DNA polymerase | - |
| V6C94_RS00320 (V6C94_00320) | - | 68587..68955 (+) | 369 | WP_001058155.1 | hypothetical protein | - |
| V6C94_RS00325 (V6C94_00325) | - | 68955..70571 (+) | 1617 | WP_001015575.1 | DUF5906 domain-containing protein | - |
| V6C94_RS00330 (V6C94_00330) | - | 70796..72475 (+) | 1680 | WP_367122004.1 | recombinase family protein | - |
| V6C94_RS00335 (V6C94_00335) | - | 72564..72902 (+) | 339 | WP_000175888.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C94_RS00340 (V6C94_00340) | - | 72996..73307 (+) | 312 | WP_001024805.1 | DUF960 family protein | - |
| V6C94_RS00345 (V6C94_00345) | - | 73322..73825 (+) | 504 | WP_001092190.1 | DUF1643 domain-containing protein | - |
| V6C94_RS00350 (V6C94_00350) | - | 73840..74061 (+) | 222 | WP_001015193.1 | hypothetical protein | - |
| V6C94_RS00355 (V6C94_00355) | - | 74134..74735 (-) | 602 | Protein_68 | DUF3387 domain-containing protein | - |
| V6C94_RS00360 (V6C94_00360) | cas1 | 76117..77022 (+) | 906 | WP_000655859.1 | type II CRISPR-associated endonuclease Cas1 | - |
| V6C94_RS00365 (V6C94_00365) | cas2 | 77022..77327 (+) | 306 | WP_000281076.1 | CRISPR-associated endonuclease Cas2 | - |
| V6C94_RS00370 (V6C94_00370) | cas10 | 77341..79614 (+) | 2274 | WP_000359017.1 | type III-A CRISPR-associated protein Cas10/Csm1 | - |
| V6C94_RS00375 (V6C94_00375) | csm2 | 79617..80042 (+) | 426 | WP_000599362.1 | type III-A CRISPR-associated protein Csm2 | - |
| V6C94_RS00380 (V6C94_00380) | csm3 | 80044..80688 (+) | 645 | WP_000286998.1 | type III-A CRISPR-associated RAMP protein Csm3 | - |
| V6C94_RS00385 (V6C94_00385) | csm4 | 80699..81607 (+) | 909 | WP_000208937.1 | type III-A CRISPR-associated RAMP protein Csm4 | - |
| V6C94_RS00390 (V6C94_00390) | csm5 | 81610..82632 (+) | 1023 | WP_000153149.1 | type III-A CRISPR-associated RAMP protein Csm5 | - |
| V6C94_RS00395 (V6C94_00395) | csm6 | 82632..83900 (+) | 1269 | WP_000865879.1 | type III-A CRISPR-associated CARF protein Csm6 | - |
| V6C94_RS00400 (V6C94_00400) | cas6 | 83897..84631 (+) | 735 | WP_000608705.1 | CRISPR-associated endoribonuclease Cas6 | - |
| V6C94_RS00405 (V6C94_00405) | - | 85741..85899 (+) | 159 | WP_000669699.1 | hypothetical protein | - |
| V6C94_RS00410 (V6C94_00410) | - | 86646..87281 (-) | 636 | WP_023350821.1 | HXXEE domain-containing protein | - |
| V6C94_RS00415 (V6C94_00415) | - | 87286..87933 (-) | 648 | WP_023350822.1 | TetR/AcrR family transcriptional regulator | - |
| V6C94_RS00420 (V6C94_00420) | - | 87943..88602 (-) | 660 | WP_023350823.1 | HXXEE domain-containing protein | - |
| V6C94_RS00425 (V6C94_00425) | - | 88972..89193 (-) | 222 | WP_023350824.1 | hypothetical protein | - |
| V6C94_RS00430 (V6C94_00430) | - | 89207..89716 (-) | 510 | WP_023350825.1 | DUF1643 domain-containing protein | - |
| V6C94_RS00435 (V6C94_00435) | - | 89732..90043 (-) | 312 | WP_023350826.1 | DUF960 family protein | - |
| V6C94_RS00440 (V6C94_00440) | - | 90130..90480 (-) | 351 | WP_023350827.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C94_RS00445 (V6C94_00445) | ccrB | 90946..92574 (-) | 1629 | WP_023350828.1 | recombinase family protein | Machinery gene |
| V6C94_RS00450 (V6C94_00450) | ccrA | 92595..93944 (-) | 1350 | WP_023350829.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62691.59 Da Isoelectric Point: 9.7324
>NTDB_id=938259 V6C94_RS00445 WP_023350828.1 90946..92574(-) (ccrB) [Staphylococcus capitis subsp. urealyticus strain Sc1191106]
MQQLKQKRVGIYVRVSTEIQNTEGYSINGQINQIRDYCQFHHFEVTDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANTLNHKGYVTKKGKPFSISSITYILSNPFYMGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHAPIISQALWDKVQARKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFD
EINTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIEFMDKSQLK
ALYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI
MQQLKQKRVGIYVRVSTEIQNTEGYSINGQINQIRDYCQFHHFEVTDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANTLNHKGYVTKKGKPFSISSITYILSNPFYMGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHAPIISQALWDKVQARKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFD
EINTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIEFMDKSQLK
ALYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI
Nucleotide
Download Length: 1629 bp
>NTDB_id=938259 V6C94_RS00445 WP_023350828.1 90946..92574(-) (ccrB) [Staphylococcus capitis subsp. urealyticus strain Sc1191106]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGTGTATCGACTGAAATCCAAAATACAGAAGGTTATAGTAT
TAATGGCCAAATCAATCAGATTAGAGACTACTGTCAATTTCACCATTTTGAAGTCACAGATATTTACGCTGATCGTGGTA
TCTCAGGAAAATCTATGAACCGTCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTACAAAACAAACCGACTGGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAGCAAAATGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAATACTTCTTCTGGAAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTTGAACGTAATAACATTGTCGAGAACGTATTCATGGGCCAAACCAGACGTGCCCAAGAAGGCTATTATCAAGGAAAT
TTACCGCTAGGCTATGACAAAATACCCGACAGTAAACACGAATTGATGATTAATCAACATGAAGCTAATATTGTAAAATA
TATTTTCGAATCTTATGCCAAAGGGCATGGCTATCGTAAAATTGCCAATACACTCAATCATAAAGGCTATGTCACTAAAA
AAGGGAAGCCTTTCAGTATAAGTTCTATTACTTATATTCTATCCAATCCCTTCTATATGGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAACGTCGTAAAGGACTGAATGATAAACCGATCATAGCTGAGGGTAAGCACGCCCCTATTAT
TAGCCAAGCATTATGGGATAAAGTGCAAGCACGTAAAAAGCAAGTCAGTCAAAAACCCCAAGTTCACGGTAAAGGAACTA
ATCTATTAACCGGTATCGTTCATTGTCCCCAATGCGGAGCACCTATGGCCGCGAGTAATACTACTAATACACTCAAAGAT
GGAACTAAGAAACGTATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTG
TCGAACGTGTTAATCAAGAAAATCAAGTCGATGTAGCTGCGCTCAATCATGATATCGCTTATAAACAACAACAATTTGAT
GAAATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATTCATGGATAAATCACAGCTCAAA
GCTTTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGACGAGAATCATAAAAAACAATTCTATGTCACTCTCAA
GCTCAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTT
TGCCTCAAACACTCTACTTTCAAATATAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGTGTATCGACTGAAATCCAAAATACAGAAGGTTATAGTAT
TAATGGCCAAATCAATCAGATTAGAGACTACTGTCAATTTCACCATTTTGAAGTCACAGATATTTACGCTGATCGTGGTA
TCTCAGGAAAATCTATGAACCGTCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTACAAAACAAACCGACTGGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAGCAAAATGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAATACTTCTTCTGGAAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTTGAACGTAATAACATTGTCGAGAACGTATTCATGGGCCAAACCAGACGTGCCCAAGAAGGCTATTATCAAGGAAAT
TTACCGCTAGGCTATGACAAAATACCCGACAGTAAACACGAATTGATGATTAATCAACATGAAGCTAATATTGTAAAATA
TATTTTCGAATCTTATGCCAAAGGGCATGGCTATCGTAAAATTGCCAATACACTCAATCATAAAGGCTATGTCACTAAAA
AAGGGAAGCCTTTCAGTATAAGTTCTATTACTTATATTCTATCCAATCCCTTCTATATGGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAACGTCGTAAAGGACTGAATGATAAACCGATCATAGCTGAGGGTAAGCACGCCCCTATTAT
TAGCCAAGCATTATGGGATAAAGTGCAAGCACGTAAAAAGCAAGTCAGTCAAAAACCCCAAGTTCACGGTAAAGGAACTA
ATCTATTAACCGGTATCGTTCATTGTCCCCAATGCGGAGCACCTATGGCCGCGAGTAATACTACTAATACACTCAAAGAT
GGAACTAAGAAACGTATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTG
TCGAACGTGTTAATCAAGAAAATCAAGTCGATGTAGCTGCGCTCAATCATGATATCGCTTATAAACAACAACAATTTGAT
GAAATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATTCATGGATAAATCACAGCTCAAA
GCTTTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGACGAGAATCATAAAAAACAATTCTATGTCACTCTCAA
GCTCAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTT
TGCCTCAAACACTCTACTTTCAAATATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
87.085 |
100 |
0.871 |