Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | V6C79_RS00365 | Genome accession | NZ_CP145251 |
| Coordinates | 76198..77547 (-) | Length | 449 a.a. |
| NCBI ID | WP_023350829.1 | Uniprot ID | - |
| Organism | Staphylococcus capitis subsp. urealyticus strain Sc1365665 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 37576..77547 | 76198..77547 | within | 0 |
Gene organization within MGE regions
Location: 37576..77547
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V6C79_RS00160 (V6C79_00160) | - | 37576..39252 (+) | 1677 | WP_000676596.1 | recombinase family protein | - |
| V6C79_RS00165 (V6C79_00165) | - | 39358..39696 (+) | 339 | WP_000171559.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C79_RS00170 (V6C79_00170) | - | 39792..40103 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| V6C79_RS00175 (V6C79_00175) | - | 40119..40625 (+) | 507 | WP_000447786.1 | DUF1643 domain-containing protein | - |
| V6C79_RS00180 (V6C79_00180) | - | 40774..41448 (-) | 675 | WP_001106056.1 | IS6-like element IS257 family transposase | - |
| V6C79_RS00185 (V6C79_00185) | - | 41532..41873 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| V6C79_RS00190 (V6C79_00190) | - | 42790..43533 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| V6C79_RS00195 (V6C79_00195) | - | 43630..44058 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| V6C79_RS00200 (V6C79_00200) | mecA | 44104..46113 (-) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| V6C79_RS00205 (V6C79_00205) | - | 46210..46317 (+) | 108 | Protein_38 | beta-lactam sensor/signal transducer MecR1 | - |
| V6C79_RS00210 (V6C79_00210) | - | 46358..47032 (+) | 675 | Protein_39 | IS6 family transposase | - |
| V6C79_RS00215 (V6C79_00215) | - | 47092..47520 (-) | 429 | WP_000671996.1 | VOC family protein | - |
| V6C79_RS00220 (V6C79_00220) | - | 47601..48530 (+) | 930 | WP_000750311.1 | HTH domain-containing protein | - |
| V6C79_RS00225 (V6C79_00225) | - | 48692..50680 (+) | 1989 | WP_001038847.1 | hypothetical protein | - |
| V6C79_RS00230 (V6C79_00230) | - | 50875..51984 (+) | 1110 | WP_000283873.1 | DNA polymerase | - |
| V6C79_RS00235 (V6C79_00235) | - | 51977..52345 (+) | 369 | WP_001058155.1 | hypothetical protein | - |
| V6C79_RS00240 (V6C79_00240) | - | 52345..53961 (+) | 1617 | WP_001015575.1 | DUF5906 domain-containing protein | - |
| V6C79_RS00245 (V6C79_00245) | - | 54186..55865 (+) | 1680 | WP_000676592.1 | recombinase family protein | - |
| V6C79_RS00250 (V6C79_00250) | - | 55954..56292 (+) | 339 | WP_000175888.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C79_RS00255 (V6C79_00255) | - | 56386..56697 (+) | 312 | WP_001024805.1 | DUF960 family protein | - |
| V6C79_RS00260 (V6C79_00260) | - | 56712..57215 (+) | 504 | WP_001092190.1 | DUF1643 domain-containing protein | - |
| V6C79_RS00265 (V6C79_00265) | - | 57230..57451 (+) | 222 | WP_001015193.1 | hypothetical protein | - |
| V6C79_RS00270 (V6C79_00270) | - | 57524..58125 (-) | 602 | Protein_51 | DUF3387 domain-containing protein | - |
| V6C79_RS00275 (V6C79_00275) | cas1 | 59720..60625 (+) | 906 | WP_000655859.1 | type II CRISPR-associated endonuclease Cas1 | - |
| V6C79_RS00280 (V6C79_00280) | cas2 | 60625..60930 (+) | 306 | WP_000281076.1 | CRISPR-associated endonuclease Cas2 | - |
| V6C79_RS00285 (V6C79_00285) | cas10 | 60944..63217 (+) | 2274 | WP_000359017.1 | type III-A CRISPR-associated protein Cas10/Csm1 | - |
| V6C79_RS00290 (V6C79_00290) | csm2 | 63220..63645 (+) | 426 | WP_000599362.1 | type III-A CRISPR-associated protein Csm2 | - |
| V6C79_RS00295 (V6C79_00295) | csm3 | 63647..64291 (+) | 645 | WP_000286998.1 | type III-A CRISPR-associated RAMP protein Csm3 | - |
| V6C79_RS00300 (V6C79_00300) | csm4 | 64302..65210 (+) | 909 | WP_000208937.1 | type III-A CRISPR-associated RAMP protein Csm4 | - |
| V6C79_RS00305 (V6C79_00305) | csm5 | 65213..66235 (+) | 1023 | WP_000153149.1 | type III-A CRISPR-associated RAMP protein Csm5 | - |
| V6C79_RS00310 (V6C79_00310) | csm6 | 66235..67503 (+) | 1269 | WP_000865879.1 | type III-A CRISPR-associated CARF protein Csm6 | - |
| V6C79_RS00315 (V6C79_00315) | cas6 | 67500..68234 (+) | 735 | WP_000608705.1 | CRISPR-associated endoribonuclease Cas6 | - |
| V6C79_RS00320 (V6C79_00320) | - | 69344..69502 (+) | 159 | WP_000669699.1 | hypothetical protein | - |
| V6C79_RS00325 (V6C79_00325) | - | 70249..70884 (-) | 636 | WP_023350821.1 | HXXEE domain-containing protein | - |
| V6C79_RS00330 (V6C79_00330) | - | 70889..71536 (-) | 648 | WP_023350822.1 | TetR/AcrR family transcriptional regulator | - |
| V6C79_RS00335 (V6C79_00335) | - | 71546..72205 (-) | 660 | WP_023350823.1 | HXXEE domain-containing protein | - |
| V6C79_RS00340 (V6C79_00340) | - | 72575..72796 (-) | 222 | WP_023350824.1 | hypothetical protein | - |
| V6C79_RS00345 (V6C79_00345) | - | 72810..73319 (-) | 510 | WP_023350825.1 | DUF1643 domain-containing protein | - |
| V6C79_RS00350 (V6C79_00350) | - | 73335..73646 (-) | 312 | WP_023350826.1 | DUF960 family protein | - |
| V6C79_RS00355 (V6C79_00355) | - | 73733..74083 (-) | 351 | WP_023350827.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C79_RS00360 (V6C79_00360) | ccrB | 74549..76177 (-) | 1629 | WP_023350828.1 | recombinase family protein | Machinery gene |
| V6C79_RS00365 (V6C79_00365) | ccrA | 76198..77547 (-) | 1350 | WP_023350829.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52477.05 Da Isoelectric Point: 10.0268
>NTDB_id=938225 V6C79_RS00365 WP_023350829.1 76198..77547(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1365665]
MKQAIGYLRQSTTKQQSLAAQKQTIKVLAEKHNIQHITFYSDKQSGRTNKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQTYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPNHSLRYYVCPKNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDADTFREQSQSFRQQSNPITSINAHQIRKVFQ
NIIQQRFTLNMLYPYIDEIHITKNKTLTGIYFKNEPLNIVNQTAQSSIA
MKQAIGYLRQSTTKQQSLAAQKQTIKVLAEKHNIQHITFYSDKQSGRTNKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQTYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPNHSLRYYVCPKNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDADTFREQSQSFRQQSNPITSINAHQIRKVFQ
NIIQQRFTLNMLYPYIDEIHITKNKTLTGIYFKNEPLNIVNQTAQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=938225 V6C79_RS00365 WP_023350829.1 76198..77547(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1365665]
ATGAAACAAGCAATTGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCTCAAAAACAAACCATCAAGGT
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTAATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAGGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
TTGAAAAATGCATTAAAGCTCATGAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAGACAAGGTAAACTAATTACAACACATGCCCCCTTTGGGTATCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAATCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGCCATTCGACACTCACAAACATGACCGTCCGAAAACCAAATCATTCATTGCGTTACTATGTCTGTCCGA
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAATCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGATACGTTCA
GAGAACAATCGCAATCATTTCGACAACAGTCAAACCCTATAACATCAATCAATGCACATCAAATTCGAAAGGTTTTTCAA
AATATCATACAACAACGTTTCACGTTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAAAAATAAAACACT
TACGGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACGGCGCAATCATCGATTGCTTAA
ATGAAACAAGCAATTGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCTCAAAAACAAACCATCAAGGT
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTAATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAGGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
TTGAAAAATGCATTAAAGCTCATGAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAGACAAGGTAAACTAATTACAACACATGCCCCCTTTGGGTATCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAATCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTCAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGCCATTCGACACTCACAAACATGACCGTCCGAAAACCAAATCATTCATTGCGTTACTATGTCTGTCCGA
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAATCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGATACGTTCA
GAGAACAATCGCAATCATTTCGACAACAGTCAAACCCTATAACATCAATCAATGCACATCAAATTCGAAAGGTTTTTCAA
AATATCATACAACAACGTTTCACGTTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAAAAATAAAACACT
TACGGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACGGCGCAATCATCGATTGCTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
91.759 |
100 |
0.918 |
| ccrA | Staphylococcus aureus N315 |
76.392 |
100 |
0.764 |