Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | V6C70_RS00615 | Genome accession | NZ_CP145235 |
| Coordinates | 73834..75462 (-) | Length | 542 a.a. |
| NCBI ID | WP_023350828.1 | Uniprot ID | T1T072 |
| Organism | Staphylococcus capitis subsp. urealyticus strain Sc1365688 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 37551..76832 | 73834..75462 | within | 0 |
Gene organization within MGE regions
Location: 37551..76832
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| V6C70_RS00415 (V6C70_00405) | - | 37551..39227 (+) | 1677 | WP_049322008.1 | recombinase family protein | - |
| V6C70_RS00420 (V6C70_00410) | - | 39333..39671 (+) | 339 | WP_000171559.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C70_RS00425 (V6C70_00415) | - | 39767..40078 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| V6C70_RS00430 (V6C70_00420) | - | 40094..40600 (+) | 507 | WP_000447786.1 | DUF1643 domain-containing protein | - |
| V6C70_RS00435 (V6C70_00425) | - | 40749..41423 (-) | 675 | WP_001106056.1 | IS6-like element IS257 family transposase | - |
| V6C70_RS00440 (V6C70_00430) | - | 41507..41848 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| V6C70_RS00445 (V6C70_00435) | - | 42765..43508 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| V6C70_RS00450 (V6C70_00440) | - | 43605..44033 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| V6C70_RS00455 (V6C70_00445) | mecA | 44079..46088 (-) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| V6C70_RS00460 (V6C70_00450) | - | 46185..46292 (+) | 108 | Protein_38 | beta-lactam sensor/signal transducer MecR1 | - |
| V6C70_RS00465 (V6C70_00455) | - | 46333..47007 (+) | 675 | Protein_39 | IS6 family transposase | - |
| V6C70_RS00470 (V6C70_00460) | - | 47067..47495 (-) | 429 | WP_000671996.1 | VOC family protein | - |
| V6C70_RS00475 (V6C70_00465) | - | 47576..48505 (+) | 930 | WP_000750311.1 | HTH domain-containing protein | - |
| V6C70_RS00480 (V6C70_00470) | - | 48667..50655 (+) | 1989 | WP_001038847.1 | hypothetical protein | - |
| V6C70_RS00485 (V6C70_00475) | - | 50850..51959 (+) | 1110 | WP_000283873.1 | DNA polymerase | - |
| V6C70_RS00490 (V6C70_00480) | - | 51952..52320 (+) | 369 | WP_001058155.1 | hypothetical protein | - |
| V6C70_RS00495 (V6C70_00485) | - | 52320..53960 (+) | 1641 | WP_367009797.1 | DUF5906 domain-containing protein | - |
| V6C70_RS00500 (V6C70_00490) | - | 54186..55865 (+) | 1680 | WP_367009798.1 | recombinase family protein | - |
| V6C70_RS00505 (V6C70_00495) | - | 55954..56292 (+) | 339 | WP_000175888.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C70_RS00510 (V6C70_00500) | - | 56386..56697 (+) | 312 | WP_001024805.1 | DUF960 family protein | - |
| V6C70_RS00515 (V6C70_00505) | - | 56712..57215 (+) | 504 | WP_001092190.1 | DUF1643 domain-containing protein | - |
| V6C70_RS00520 (V6C70_00510) | - | 57230..57451 (+) | 222 | WP_001015193.1 | hypothetical protein | - |
| V6C70_RS00525 (V6C70_00515) | - | 57524..58125 (-) | 602 | Protein_51 | DUF3387 domain-containing protein | - |
| V6C70_RS00530 (V6C70_00520) | cas1 | 59005..59910 (+) | 906 | WP_000655859.1 | type II CRISPR-associated endonuclease Cas1 | - |
| V6C70_RS00535 (V6C70_00525) | cas2 | 59910..60215 (+) | 306 | WP_000281076.1 | CRISPR-associated endonuclease Cas2 | - |
| V6C70_RS00540 (V6C70_00530) | cas10 | 60229..62502 (+) | 2274 | WP_000359017.1 | type III-A CRISPR-associated protein Cas10/Csm1 | - |
| V6C70_RS00545 (V6C70_00535) | csm2 | 62505..62930 (+) | 426 | WP_000599362.1 | type III-A CRISPR-associated protein Csm2 | - |
| V6C70_RS00550 (V6C70_00540) | csm3 | 62932..63576 (+) | 645 | WP_000286998.1 | type III-A CRISPR-associated RAMP protein Csm3 | - |
| V6C70_RS00555 (V6C70_00545) | csm4 | 63587..64495 (+) | 909 | WP_000208937.1 | type III-A CRISPR-associated RAMP protein Csm4 | - |
| V6C70_RS00560 (V6C70_00550) | csm5 | 64498..65520 (+) | 1023 | WP_000153149.1 | type III-A CRISPR-associated RAMP protein Csm5 | - |
| V6C70_RS00565 (V6C70_00555) | csm6 | 65520..66788 (+) | 1269 | WP_000865879.1 | type III-A CRISPR-associated CARF protein Csm6 | - |
| V6C70_RS00570 (V6C70_00560) | cas6 | 66785..67519 (+) | 735 | WP_000608705.1 | CRISPR-associated endoribonuclease Cas6 | - |
| V6C70_RS00575 (V6C70_00565) | - | 68629..68787 (+) | 159 | WP_000669699.1 | hypothetical protein | - |
| V6C70_RS00580 (V6C70_00570) | - | 69534..70169 (-) | 636 | WP_023350821.1 | HXXEE domain-containing protein | - |
| V6C70_RS00585 (V6C70_00575) | - | 70174..70821 (-) | 648 | WP_023350822.1 | TetR/AcrR family transcriptional regulator | - |
| V6C70_RS00590 (V6C70_00580) | - | 70831..71490 (-) | 660 | WP_023350823.1 | HXXEE domain-containing protein | - |
| V6C70_RS00595 (V6C70_00585) | - | 71860..72081 (-) | 222 | WP_023350824.1 | hypothetical protein | - |
| V6C70_RS00600 (V6C70_00590) | - | 72095..72604 (-) | 510 | WP_023350825.1 | DUF1643 domain-containing protein | - |
| V6C70_RS00605 (V6C70_00595) | - | 72620..72931 (-) | 312 | WP_023350826.1 | DUF960 family protein | - |
| V6C70_RS00610 (V6C70_00600) | - | 73018..73368 (-) | 351 | WP_023350827.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| V6C70_RS00615 (V6C70_00605) | ccrB | 73834..75462 (-) | 1629 | WP_023350828.1 | recombinase family protein | Machinery gene |
| V6C70_RS00620 (V6C70_00610) | ccrA | 75483..76832 (-) | 1350 | WP_023350829.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62691.59 Da Isoelectric Point: 9.7324
>NTDB_id=937989 V6C70_RS00615 WP_023350828.1 73834..75462(-) (ccrB) [Staphylococcus capitis subsp. urealyticus strain Sc1365688]
MQQLKQKRVGIYVRVSTEIQNTEGYSINGQINQIRDYCQFHHFEVTDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANTLNHKGYVTKKGKPFSISSITYILSNPFYMGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHAPIISQALWDKVQARKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFD
EINTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIEFMDKSQLK
ALYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI
MQQLKQKRVGIYVRVSTEIQNTEGYSINGQINQIRDYCQFHHFEVTDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANTLNHKGYVTKKGKPFSISSITYILSNPFYMGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHAPIISQALWDKVQARKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQENQVDVAALNHDIAYKQQQFD
EINTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIEFMDKSQLK
ALYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI
Nucleotide
Download Length: 1629 bp
>NTDB_id=937989 V6C70_RS00615 WP_023350828.1 73834..75462(-) (ccrB) [Staphylococcus capitis subsp. urealyticus strain Sc1365688]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGTGTATCGACTGAAATCCAAAATACAGAAGGTTATAGTAT
TAATGGCCAAATCAATCAGATTAGAGACTACTGTCAATTTCACCATTTTGAAGTCACAGATATTTACGCTGATCGTGGTA
TCTCAGGAAAATCTATGAACCGTCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTACAAAACAAACCGACTGGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAGCAAAATGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAATACTTCTTCTGGAAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTTGAACGTAATAACATTGTCGAGAACGTATTCATGGGCCAAACCAGACGTGCCCAAGAAGGCTATTATCAAGGAAAT
TTACCGCTAGGCTATGACAAAATACCCGACAGTAAACACGAATTGATGATTAATCAACATGAAGCTAATATTGTAAAATA
TATTTTCGAATCTTATGCCAAAGGGCATGGCTATCGTAAAATTGCCAATACACTCAATCATAAAGGCTATGTCACTAAAA
AAGGGAAGCCTTTCAGTATAAGTTCTATTACTTATATTCTATCCAATCCCTTCTATATGGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAACGTCGTAAAGGACTGAATGATAAACCGATCATAGCTGAGGGTAAGCACGCCCCTATTAT
TAGCCAAGCATTATGGGATAAAGTGCAAGCACGTAAAAAGCAAGTCAGTCAAAAACCCCAAGTTCACGGTAAAGGAACTA
ATCTATTAACCGGTATCGTTCATTGTCCCCAATGCGGAGCACCTATGGCCGCGAGTAATACTACTAATACACTCAAAGAT
GGAACTAAGAAACGTATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTG
TCGAACGTGTTAATCAAGAAAATCAAGTCGATGTAGCTGCGCTCAATCATGATATCGCTTATAAACAACAACAATTTGAT
GAAATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATTCATGGATAAATCACAGCTCAAA
GCTTTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGACGAGAATCATAAAAAACAATTCTATGTCACTCTCAA
GCTCAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTT
TGCCTCAAACACTCTACTTTCAAATATAA
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGTGTATCGACTGAAATCCAAAATACAGAAGGTTATAGTAT
TAATGGCCAAATCAATCAGATTAGAGACTACTGTCAATTTCACCATTTTGAAGTCACAGATATTTACGCTGATCGTGGTA
TCTCAGGAAAATCTATGAACCGTCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTACAAAACAAACCGACTGGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAGCAAAATGTCGA
ATTTTTCAGTTTGTCTGAACGTATGGAAGTCAATACTTCTTCTGGAAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTTGAACGTAATAACATTGTCGAGAACGTATTCATGGGCCAAACCAGACGTGCCCAAGAAGGCTATTATCAAGGAAAT
TTACCGCTAGGCTATGACAAAATACCCGACAGTAAACACGAATTGATGATTAATCAACATGAAGCTAATATTGTAAAATA
TATTTTCGAATCTTATGCCAAAGGGCATGGCTATCGTAAAATTGCCAATACACTCAATCATAAAGGCTATGTCACTAAAA
AAGGGAAGCCTTTCAGTATAAGTTCTATTACTTATATTCTATCCAATCCCTTCTATATGGGTAAAATTCAATTTGCGAAG
TACAAAGATTGGAATGAAAAACGTCGTAAAGGACTGAATGATAAACCGATCATAGCTGAGGGTAAGCACGCCCCTATTAT
TAGCCAAGCATTATGGGATAAAGTGCAAGCACGTAAAAAGCAAGTCAGTCAAAAACCCCAAGTTCACGGTAAAGGAACTA
ATCTATTAACCGGTATCGTTCATTGTCCCCAATGCGGAGCACCTATGGCCGCGAGTAATACTACTAATACACTCAAAGAT
GGAACTAAGAAACGTATTCGCTATTATTCTTGTAGTAACTTTCGCAACAAAGGATCAAAGGTATGTTCAGCCAATAGTGT
TAGAGCTGATGTTATCGAAAAGTATGTTATGGATCAAATACTCGAAATAGTCAAAAGTGATAAAGTTATCAAACAAGTTG
TCGAACGTGTTAATCAAGAAAATCAAGTCGATGTAGCTGCGCTCAATCATGATATCGCTTATAAACAACAACAATTTGAT
GAAATTAACACTAAACTTAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATTCATGGATAAATCACAGCTCAAA
GCTTTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGACGAGAATCATAAAAAACAATTCTATGTCACTCTCAA
GCTCAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTT
TGCCTCAAACACTCTACTTTCAAATATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
87.085 |
100 |
0.871 |