Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   V6C55_RS00200 Genome accession   NZ_CP145224
Coordinates   44609..45958 (-) Length   449 a.a.
NCBI ID   WP_310990885.1    Uniprot ID   -
Organism   Staphylococcus capitis subsp. urealyticus strain Sc1365701     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 36194..51239 44609..45958 within 0


Gene organization within MGE regions


Location: 36194..51239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6C55_RS00160 (V6C55_00160) mecA 36194..38203 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  V6C55_RS00165 (V6C55_00165) - 38300..39286 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  V6C55_RS00170 (V6C55_00170) - 39258..39518 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  V6C55_RS00175 (V6C55_00175) - 39509..41116 (-) 1608 Protein_32 IS1182 family transposase -
  V6C55_RS00180 (V6C55_00180) - 41168..41674 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  V6C55_RS00185 (V6C55_00185) - 41689..42000 (-) 312 WP_000700851.1 DUF960 family protein -
  V6C55_RS00190 (V6C55_00190) - 42087..42437 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  V6C55_RS00195 (V6C55_00195) ccrB 42959..44587 (-) 1629 WP_001186608.1 recombinase family protein Machinery gene
  V6C55_RS00200 (V6C55_00200) ccrA 44609..45958 (-) 1350 WP_310990885.1 recombinase family protein Machinery gene
  V6C55_RS00205 (V6C55_00205) - 46192..47985 (-) 1794 WP_021758190.1 DUF927 domain-containing protein -
  V6C55_RS00210 (V6C55_00210) - 47985..48278 (-) 294 WP_021758191.1 single-stranded DNA-binding protein -
  V6C55_RS00215 (V6C55_00215) - 48513..49654 (+) 1142 WP_089535815.1 IS3 family transposase -
  V6C55_RS00220 (V6C55_00220) - 49725..51239 (-) 1515 WP_021758193.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52657.29 Da        Isoelectric Point: 9.9639

>NTDB_id=937918 V6C55_RS00200 WP_310990885.1 44609..45958(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1365701]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQVTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHIIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=937918 V6C55_RS00200 WP_310990885.1 44609..45958(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1365701]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAGTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATTAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTATGTGATTTCAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAGCAAACACAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAACACATCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATTGTCAATCAAACCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.773

100

0.978
  ccrA Staphylococcus aureus COL

74.833

100

0.748