Detailed information NTG0937890

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V6C75_RS04765
• Genome accession: NZ_CP145221
• Coordinates: 1006687..1007733 (+)
• Length: 348 a.a.
• NCBI ID: WP_002435929.1
• Uniprot ID: A0A0S4MEI3
• Organism: Staphylococcus capitis subsp. urealyticus strain Sc1365706
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1001687..1012733

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6C75_RS04735	-	1001952..1002677 (+)	726	WP_002469718.1	type 1 glutamine amidotransferase	-
V6C75_RS04740	isaB	1002906..1003448 (+)	543	WP_023350030.1	immunodominant staphylococcal antigen IsaB family protein	-
V6C75_RS04745	-	1003526..1004515 (-)	990	WP_002435886.1	FUSC family protein	-
V6C75_RS04750	map	1004688..1005443 (+)	756	WP_002435911.1	type I methionyl aminopeptidase	-
V6C75_RS04755	-	1005588..1005974 (+)	387	WP_002453601.1	hypothetical protein	-
V6C75_RS04760	liaF	1005989..1006690 (+)	702	WP_047796452.1	cell wall-active antibiotics response protein LiaF	-
V6C75_RS04765	vraS	1006687..1007733 (+)	1047	WP_002435929.1	sensor histidine kinase	Regulator
V6C75_RS04770	vraR	1007723..1008352 (+)	630	WP_002469716.1	two-component system response regulator VraR	Regulator
V6C75_RS04775	-	1008417..1009670 (-)	1254	WP_002435884.1	YihY/virulence factor BrkB family protein	-
V6C75_RS04780	-	1010007..1010291 (-)	285	WP_002435890.1	hypothetical protein	-
V6C75_RS04785	-	1010298..1010762 (-)	465	WP_058121615.1	low molecular weight protein-tyrosine-phosphatase	-
V6C75_RS04790	-	1010903..1011109 (+)	207	WP_002435959.1	DUF1128 domain-containing protein	-
V6C75_RS04795	-	1011123..1012364 (+)	1242	WP_047796450.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40136.57 Da
• Isoelectric Point: 6.0600

>NTDB_id=937890 V6C75_RS04765 WP_002435929.1 1006687..1007733(+) (vraS) [Staphylococcus capitis subsp. urealyticus strain Sc1365706]
MNHYLRAIGSMLILVYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNILIILLCIIVGSVLAYKINQQNDWLKS
QIERSIEGETVGINDQNLELYSETLEIYHTLVPLNQELHRLRMKTQNMTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGSKVTVELFNKEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDESNGD

Nucleotide

• Length: 1047 bp

>NTDB_id=937890 V6C75_RS04765 WP_002435929.1 1006687..1007733(+) (vraS) [Staphylococcus capitis subsp. urealyticus strain Sc1365706]
ATGAATCACTACTTGAGAGCAATTGGTTCAATGCTAATACTTGTATATAGCATGCTAACTGCTTTTTTATTCATTGATAA
GGTGTTCGTCAATATTATTTATTTTCAAGGGATGTTTTACACCCAAATTTTTGGAATACCAGTATTTTTATTCCTAAATA
TATTAATCATCTTACTATGTATTATCGTTGGCTCTGTGTTAGCGTATAAAATCAATCAACAAAATGATTGGCTTAAGTCA
CAAATTGAAAGGTCTATTGAAGGTGAAACAGTTGGCATTAATGATCAAAATCTAGAGTTATACAGTGAAACGTTAGAAAT
TTACCATACTTTAGTTCCTTTAAATCAAGAATTACACCGATTGAGAATGAAAACGCAGAATATGACCAATGAAAATTATA
ATATGAATGATGTAAAAGTGAAGAAAATCATTGAAGACGAACGTCAACGTTTAGCAAGAGAACTACATGACTCAGTTAGT
CAGCAATTATTTGCAGCAAGTATGATGTTGTCAGCGATTAAAGAGTCAAAATTAGAACCACCTTTAGACCAACAAATACC
TGTATTAGAGAAGATGGTTCAAGACTCTCAGCTCGAAATGAGAGCATTACTACTACATCTAAGACCTATTGGTTTGAAAG
ACAAATCATTAGGGGAGGGTATTAAAGATTTAGTTATTGATCTTCAAAAGAAAGTCCCTATGAAAGTTGTTCATGAAATT
CAAGATTTCAAAGTACCAAAAGGGATAGAAGATCATCTGTTTAGAATCACTCAAGAGGCTATTTCTAATACATTACGACA
CTCTAATGGTTCTAAGGTAACAGTTGAATTATTTAATAAAGAAGATTATTTACTACTTAGAATTCAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTTGAACAGAGTTATGGATTAAAAAATATGAGAGAACGTGCTTTAGAGATTGGTGCCACA
TTCCATATCGTATCGTTACCGGATTCAGGTACGAGAATAGAAGTTAAAGCACCATTGAATAAGGAGGATGAATCAAATGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A0S4MEI3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.586	98.563	0.922