Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   V6C61_RS00185 Genome accession   NZ_CP145198
Coordinates   37966..39327 (-) Length   453 a.a.
NCBI ID   WP_057504845.1    Uniprot ID   -
Organism   Staphylococcus capitis subsp. urealyticus strain Sc1516945     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 36634..72669 37966..39327 within 0


Gene organization within MGE regions


Location: 36634..72669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6C61_RS00185 (V6C61_00180) ccrA 37966..39327 (-) 1362 WP_057504845.1 cassette chromosome recombinase CcrA Machinery gene
  V6C61_RS00190 (V6C61_00185) cch1 39514..41283 (-) 1770 WP_031870521.1 cassette chromosome replicative helicase -
  V6C61_RS00195 (V6C61_00190) ssb 41283..41579 (-) 297 WP_031870522.1 cassette chromosome ssDNA-binding protein -
  V6C61_RS00200 (V6C61_00195) - 41771..42805 (-) 1035 WP_031870523.1 hypothetical protein -
  V6C61_RS00205 (V6C61_00200) - 42937..43710 (+) 774 WP_367019707.1 hypothetical protein -
  V6C61_RS00210 (V6C61_00205) - 43765..44256 (+) 492 Protein_39 sulfite exporter TauE/SafE family protein -
  V6C61_RS00215 (V6C61_00210) - 44472..49910 (+) 5439 WP_367019708.1 E domain-containing protein -
  V6C61_RS00220 (V6C61_00215) - 50034..51650 (+) 1617 WP_000393940.1 hypothetical protein -
  V6C61_RS00225 (V6C61_00220) - 51810..53321 (-) 1512 WP_000640645.1 glycosyltransferase family 4 protein -
  V6C61_RS00230 (V6C61_00225) - 53344..55398 (-) 2055 WP_260832840.1 Mur ligase family protein -
  V6C61_RS00235 (V6C61_00230) - 56385..56711 (+) 327 WP_000624048.1 helix-turn-helix domain-containing protein -
  V6C61_RS00240 (V6C61_00235) - 56748..57581 (+) 834 WP_000694291.1 CPBP family intramembrane glutamic endopeptidase -
  V6C61_RS00245 (V6C61_00240) - 58267..59040 (+) 774 WP_000998885.1 hypothetical protein -
  V6C61_RS00250 (V6C61_00245) - 59278..59637 (-) 360 WP_000432280.1 DUF4870 domain-containing protein -
  V6C61_RS00255 (V6C61_00250) - 59802..60872 (-) 1071 WP_002499602.1 NAD(P)H-dependent flavin oxidoreductase -
  V6C61_RS00260 (V6C61_00255) - 60885..61751 (-) 867 WP_001052247.1 LysR family transcriptional regulator -
  V6C61_RS00265 (V6C61_00260) - 61738..62928 (-) 1191 WP_000716034.1 YbfB/YjiJ family MFS transporter -
  V6C61_RS00270 (V6C61_00265) - 63139..63813 (+) 675 Protein_51 IS6 family transposase -
  V6C61_RS00275 (V6C61_00270) - 63873..64301 (-) 429 WP_000671997.1 VOC family protein -
  V6C61_RS00280 (V6C61_00275) - 64382..65311 (+) 930 WP_002504713.1 helix-turn-helix transcriptional regulator -
  V6C61_RS00285 (V6C61_00280) - 65473..67485 (+) 2013 WP_012088687.1 hypothetical protein -
  V6C61_RS00290 (V6C61_00285) - 67655..68764 (+) 1110 WP_002437509.1 DNA polymerase -
  V6C61_RS00295 (V6C61_00290) - 68757..69128 (+) 372 WP_002437511.1 hypothetical protein -
  V6C61_RS00300 (V6C61_00295) - 69125..70768 (+) 1644 WP_141489472.1 DUF5906 domain-containing protein -
  V6C61_RS00305 (V6C61_00300) ccrC 70993..72669 (+) 1677 WP_002504707.1 cassette chromosome recombinase CcrC -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53205.31 Da        Isoelectric Point: 9.8623

>NTDB_id=937642 V6C61_RS00185 WP_057504845.1 37966..39327(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1516945]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSHVTFYDDKKTGRHTKRSGYQKMVEMITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHQVTIISVNDGYFDLSKEFDRFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYRYK
QGHFVVHEEEAYTVKVVYCWYLQGLGYKKISQHLDNNPKLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNEAYHTCPFKGINAQMIETEILST
CKAYCDNQSFHDKLNKTVLKALKHQQIKHKETHLTQAQLIEKLAQNRIDVKTFKRLSASCKSEENYPTYSTYQIDDKLKY
VIKNKITLQDIAPLIDEITITQTKQLQGIYFKNTPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=937642 V6C61_RS00185 WP_057504845.1 37966..39327(-) (ccrA) [Staphylococcus capitis subsp. urealyticus strain Sc1516945]
ATGGAAGAAGCCATTGCTTACGTACGTCAAAGTACATTAAAACAACAAAGCTTAGCGACACAGAAATCACTTATTATGGA
TACTGCTAAACAATATGGATGGTCTCATGTGACGTTTTATGATGATAAAAAAACAGGTCGACATACAAAACGTTCGGGCT
ATCAAAAAATGGTAGAAATGATTACATCTGGAAAATGTAAAGTATTATGTTGTTATCGTCTGAATCGACTTCATCGTAAT
TTGAAAAACGCTATACAATTCTTTGAAATTTGTAAAAAGCATCAAGTCACAATCATCAGCGTGAATGATGGCTATTTTGA
CTTATCTAAAGAATTTGATCGCTTTCGCCTAAACATACTTATGAGTCTAGCTGAAATGGAGTCTAATAATATCAGTGAAC
AGACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGTTATCGTTACAAA
CAAGGTCATTTTGTTGTACATGAAGAAGAAGCGTATACAGTCAAAGTGGTCTATTGCTGGTACTTACAAGGGCTAGGCTA
CAAAAAAATTTCCCAACATTTAGATAACAACCCTAAGCTTATTCCACGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAATTATTGTGGTCGTGTCATTAATAAATATGGAACATTTAATGATATCGTTCCACCTATTATTGATATTGATACG
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGTTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAAAATTACTCTCTACGTTACTACGTTTGTCCTA
AGAATATGAATGAAGCTTATCATACGTGTCCATTTAAAGGTATCAATGCACAAATGATTGAAACAGAGATCCTCAGCACT
TGTAAAGCGTATTGTGACAATCAATCATTTCATGACAAATTAAATAAGACAGTACTAAAAGCTCTAAAACACCAACAAAT
AAAGCATAAAGAAACCCATCTAACACAAGCACAATTGATTGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTATCCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGACATAGCACCTTTGATTGATGAAATTACAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAATACTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(168-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

54.853

97.792

0.536
  ccrA Staphylococcus aureus N315

51.242

97.792

0.501