Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   V5F86_RS06220 Genome accession   NZ_CP145137
Coordinates   1223713..1224369 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus spizizenii strain kcgeb_sc     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1218713..1229369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5F86_RS06190 (V5F86_06195) oppF 1218977..1219894 (+) 918 WP_072182806.1 oligopeptide ABC transporter ATP-binding protein OppF -
  V5F86_RS06195 (V5F86_06200) - 1219995..1221194 (+) 1200 Protein_1155 MFS transporter -
  V5F86_RS06200 (V5F86_06205) - 1221372..1221950 (+) 579 WP_338444128.1 GNAT family N-acetyltransferase -
  V5F86_RS06205 (V5F86_06210) spx 1222131..1222526 (+) 396 WP_003239281.1 transcriptional regulator Spx -
  V5F86_RS06210 (V5F86_06215) - 1222781..1223437 (-) 657 WP_338444129.1 TerC family protein -
  V5F86_RS06215 (V5F86_06220) - 1223621..1223746 (+) 126 WP_120698858.1 hypothetical protein -
  V5F86_RS06220 (V5F86_06225) mecA 1223713..1224369 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  V5F86_RS06225 (V5F86_06230) - 1224364..1224485 (-) 122 Protein_1161 hypothetical protein -
  V5F86_RS06230 (V5F86_06235) coiA 1224529..1225680 (+) 1152 WP_338444130.1 competence protein CoiA Machinery gene
  V5F86_RS06235 (V5F86_06240) pepF 1225910..1227739 (+) 1830 WP_338444497.1 oligoendopeptidase F -
  V5F86_RS06240 (V5F86_06245) - 1227777..1227944 (-) 168 WP_041520918.1 hypothetical protein -
  V5F86_RS06245 (V5F86_06250) spxH 1228258..1229157 (-) 900 WP_014113378.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=937402 V5F86_RS06220 WP_014113374.1 1223713..1224369(+) (mecA) [Bacillus spizizenii strain kcgeb_sc]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=937402 V5F86_RS06220 WP_014113374.1 1223713..1224369(+) (mecA) [Bacillus spizizenii strain kcgeb_sc]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTGGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991