Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   AAX72_RS00675 Genome accession   NZ_CP145109
Coordinates   84431..86236 (-) Length   601 a.a.
NCBI ID   WP_024855562.1    Uniprot ID   -
Organism   Levilactobacillus brevis strain 47f     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 78743..94961 84431..86236 within 0
IScluster/Tn 86562..87337 84431..86236 flank 326


Gene organization within MGE regions


Location: 78743..94961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAX72_RS00645 (AAX72_000645) - 78743..79666 (+) 924 WP_024855102.1 IS30 family transposase -
  AAX72_RS00650 (AAX72_000650) - 80034..80933 (-) 900 WP_011668196.1 RluA family pseudouridine synthase -
  AAX72_RS00655 (AAX72_000655) - 80930..81733 (-) 804 WP_021740943.1 NAD kinase -
  AAX72_RS00660 (AAX72_000660) - 81735..82394 (-) 660 WP_011668198.1 GTP pyrophosphokinase family protein -
  AAX72_RS00665 (AAX72_000665) - 82708..83346 (+) 639 WP_047021752.1 ClpXP adapter SpxH family protein -
  AAX72_RS00670 (AAX72_000670) - 83509..84372 (+) 864 WP_011668200.1 DegV family protein -
  AAX72_RS00675 (AAX72_000675) pepF 84431..86236 (-) 1806 WP_024855562.1 oligoendopeptidase F Regulator
  AAX72_RS00680 (AAX72_000680) - 86562..87337 (+) 776 WP_289668966.1 IS5-like element ISLpl3 family transposase -
  AAX72_RS00685 (AAX72_000685) - 87341..88252 (-) 912 WP_260145688.1 competence protein CoiA family protein -
  AAX72_RS00690 (AAX72_000690) trmB 88379..89026 (-) 648 WP_015473913.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  AAX72_RS00695 (AAX72_000695) - 89092..89883 (-) 792 WP_011668204.1 phosphotransferase family protein -
  AAX72_RS00700 (AAX72_000700) - 89945..91171 (-) 1227 WP_011668205.1 ABC transporter permease -
  AAX72_RS00705 (AAX72_000705) - 91168..91902 (-) 735 WP_011668206.1 ABC transporter ATP-binding protein -
  AAX72_RS00710 (AAX72_000710) - 92112..92570 (+) 459 WP_187128170.1 HIT family protein -
  AAX72_RS00715 (AAX72_000715) - 92573..92893 (+) 321 WP_011668208.1 hypothetical protein -
  AAX72_RS00720 (AAX72_000720) - 93006..93923 (+) 918 WP_011668209.1 peptidylprolyl isomerase PrsA -
  AAX72_RS00725 (AAX72_000725) - 93987..94955 (-) 969 WP_041816463.1 HD domain-containing protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 67159.29 Da        Isoelectric Point: 4.8810

>NTDB_id=937210 AAX72_RS00675 WP_024855562.1 84431..86236(-) (pepF) [Levilactobacillus brevis strain 47f]
MKQIPKRSEVPTALTWDLTTIFPDEAAFKTAIAAIKAQITVVAGLKGQLAQSGVALYRVTTAVFDLNRQLERVYVYASLN
NDQDTGNAAAQALMGQAESLVATVGAATAWFEPEVLALSADQLQTLIDNDPRLADYQHVFDVLGQQRAHTLSVAEEKLLA
GASDIFGASAKTYSVLSDADLKFPVVQDEAGNDVRLSEGLYGVLLQSTTPRVRQQAFEALYSVYQQFRHTFAATLASEVK
THNFSAETRHYASARAAAMSRNNVPAVVYDTLVETVNEHLDSLHRYVNLRKEILALPQLHMYDLYTPITGEPSLKYTYQE
AQEMALKALAVLGPDYTANVQKMFDGRAIDVVENQGKRTGAYSGGMYDTKPYILLNWQDSLESLFTLVHEMGHSMHSHYT
RTNQPYQYGDYSIFVAEIASTTNENLLTDYLLKTQTDPKVRAYVLNHYLDGFKGTVYRQTQFAEFEDYIHQQDAAGETLT
ADFMSDFYGKLNQRYYGDGVISDPQIADEWTRIPHFYYDYYVYQYATGFAAATTLSQRILSGDEAKRDAYLAYLKAGSSA
LPLDVMKQAGVDMTQPGYLQTAFATFDERLAEFTQLAHELK

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=937210 AAX72_RS00675 WP_024855562.1 84431..86236(-) (pepF) [Levilactobacillus brevis strain 47f]
GTGAAACAAATTCCGAAACGATCAGAGGTTCCCACGGCACTGACTTGGGACCTGACAACTATTTTTCCCGACGAAGCAGC
TTTTAAGACCGCAATTGCCGCGATTAAAGCGCAAATAACGGTTGTGGCCGGCTTGAAGGGACAATTGGCCCAAAGTGGGG
TCGCGTTATATCGTGTCACGACGGCGGTATTTGATTTGAATCGCCAGTTGGAGCGGGTATACGTCTATGCGTCTTTAAAC
AATGATCAGGATACCGGCAATGCTGCGGCCCAAGCATTAATGGGGCAGGCCGAGAGCTTGGTGGCAACTGTGGGTGCCGC
CACGGCTTGGTTTGAACCTGAGGTATTGGCCTTGTCAGCGGATCAGCTGCAAACGCTGATTGATAACGACCCCCGGCTGG
CAGATTATCAGCATGTGTTTGACGTATTGGGCCAGCAACGGGCACATACGCTGTCAGTGGCGGAGGAAAAATTGTTAGCG
GGGGCTAGTGATATCTTTGGTGCATCTGCTAAAACTTATAGTGTGCTGAGTGATGCTGATCTAAAGTTTCCGGTTGTTCA
AGACGAGGCCGGCAACGATGTGCGACTGTCAGAAGGACTGTATGGTGTTTTGCTACAATCCACAACACCACGGGTGCGGC
AGCAGGCCTTTGAAGCATTATATTCGGTTTATCAACAATTCCGACATACCTTTGCTGCAACCTTGGCGAGTGAAGTCAAA
ACGCATAATTTTAGCGCTGAGACGCGTCACTATGCGAGTGCCAGAGCGGCCGCAATGAGTCGCAACAATGTGCCAGCAGT
GGTCTATGATACCTTGGTGGAAACAGTCAATGAGCATTTAGACTCGCTGCATCGCTATGTTAATTTGCGCAAAGAGATTT
TGGCCTTGCCGCAACTGCACATGTACGACCTGTATACGCCAATTACGGGTGAACCCAGCTTGAAATATACCTACCAAGAA
GCACAAGAGATGGCGTTAAAGGCACTAGCAGTTTTGGGACCGGATTACACTGCCAATGTTCAAAAGATGTTTGATGGTCG
GGCAATTGATGTGGTTGAAAATCAGGGTAAGCGAACGGGCGCTTACTCAGGCGGGATGTATGATACCAAACCGTATATTT
TGTTGAATTGGCAAGATAGCTTGGAAAGCTTGTTCACGTTGGTTCATGAGATGGGACACAGCATGCATAGCCATTACACT
CGGACAAATCAACCGTACCAGTATGGTGATTATTCAATCTTTGTTGCGGAAATTGCCTCGACAACGAATGAAAACTTGCT
GACGGACTATCTGTTGAAAACCCAGACTGACCCCAAGGTGCGAGCTTACGTATTAAACCATTATCTGGATGGCTTTAAAG
GCACGGTATACCGCCAGACGCAGTTTGCAGAATTTGAGGACTACATTCACCAACAGGATGCCGCTGGCGAAACTCTGACA
GCTGACTTCATGAGTGATTTCTACGGCAAACTTAATCAGCGTTATTACGGTGATGGCGTGATTTCCGATCCACAAATCGC
TGATGAATGGACCCGAATTCCACATTTCTACTATGACTACTATGTGTACCAGTACGCAACCGGGTTTGCGGCGGCTACGA
CGTTATCGCAACGAATTTTGAGTGGCGACGAGGCAAAGCGGGATGCCTACTTGGCCTATCTAAAGGCGGGAAGTTCTGCC
TTACCACTTGATGTGATGAAACAAGCGGGCGTCGATATGACGCAACCGGGCTATTTGCAGACGGCTTTTGCAACGTTCGA
CGAGCGTTTGGCAGAATTCACGCAATTGGCGCATGAATTAAAATAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(204-584)

Oligopeptidase F (Peptidase_M3_N)

(114-183)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50

98.17

0.491