Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   LLL8_RS11610 Genome accession   NZ_AP025700
Coordinates   2333345..2334373 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis strain L8     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 2328345..2339373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLL8_RS11590 (LLL8_22670) - 2329419..2330276 (-) 858 WP_058203259.1 Rgg/GadR/MutR family transcriptional regulator -
  LLL8_RS11595 (LLL8_22680) - 2330387..2331526 (-) 1140 WP_012898644.1 MFS transporter -
  LLL8_RS11600 (LLL8_22690) kwcM 2331523..2332842 (-) 1320 WP_058207975.1 KxxxW cyclic peptide radical SAM maturase -
  LLL8_RS11605 (LLL8_22700) - 2332910..2333023 (-) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  LLL8_RS11610 (LLL8_22710) sepM 2333345..2334373 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  LLL8_RS11615 (LLL8_22720) coaD 2334360..2334857 (-) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  LLL8_RS11620 (LLL8_22730) rsmD 2334905..2335444 (-) 540 WP_015427191.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  LLL8_RS11625 (LLL8_22740) - 2335615..2336835 (-) 1221 WP_251899980.1 MFS transporter -
  LLL8_RS11630 (LLL8_22750) lmrP 2336918..2338144 (-) 1227 WP_012898648.1 multidrug efflux MFS transporter LmrP -
  LLL8_RS11635 (LLL8_22760) - 2338332..2338826 (+) 495 WP_017865181.1 RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=93719 LLL8_RS11610 WP_003132657.1 2333345..2334373(-) (sepM) [Lactococcus lactis strain L8]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=93719 LLL8_RS11610 WP_003132657.1 2333345..2334373(-) (sepM) [Lactococcus lactis strain L8]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491

Multiple sequence alignment