Detailed information    

insolico Bioinformatically predicted

Overview


Name   recA   Type   Machinery gene
Locus tag   V5F96_RS04185 Genome accession   NZ_CP145059
Coordinates   808858..809904 (+) Length   348 a.a.
NCBI ID   WP_003688695.1    Uniprot ID   Q5F8M9
Organism   Neisseria gonorrhoeae strain WHO_W_2024     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 801773..877262 808858..809904 within 0


Gene organization within MGE regions


Location: 801773..877262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5F96_RS04155 (V5F96_04165) - 801773..802843 (-) 1071 WP_003691208.1 integrase arm-type DNA-binding domain-containing protein -
  V5F96_RS04160 (V5F96_04170) - 803052..803831 (-) 780 WP_003688701.1 ferredoxin--NADP reductase -
  V5F96_RS04165 (V5F96_04175) - 804423..804632 (-) 210 WP_003688699.1 hypothetical protein -
  V5F96_RS04170 (V5F96_04180) dinB 804731..805789 (+) 1059 WP_003688698.1 DNA polymerase IV -
  V5F96_RS04175 (V5F96_04185) rep 805859..807874 (-) 2016 WP_012503651.1 DNA helicase Rep -
  V5F96_RS04180 (V5F96_04190) aroD 807894..808658 (-) 765 WP_003688696.1 type I 3-dehydroquinate dehydratase -
  V5F96_RS04185 (V5F96_04195) recA 808858..809904 (+) 1047 WP_003688695.1 recombinase RecA Machinery gene
  V5F96_RS04190 (V5F96_04200) - 810557..810892 (-) 336 WP_003688693.1 YbaB/EbfC family nucleoid-associated protein -
  V5F96_RS04195 (V5F96_04205) dnaX 810973..813096 (-) 2124 WP_003691207.1 DNA polymerase III subunit gamma/tau -
  V5F96_RS04200 (V5F96_04210) mutL 813191..815167 (-) 1977 WP_003688688.1 DNA mismatch repair endonuclease MutL -
  V5F96_RS04205 (V5F96_04215) - 815311..815496 (+) 186 WP_003688687.1 DUF3460 family protein -
  V5F96_RS04210 (V5F96_04220) - 815507..816175 (+) 669 WP_003688686.1 class I SAM-dependent methyltransferase -
  V5F96_RS04215 (V5F96_04225) - 816175..816888 (+) 714 WP_003688685.1 tol-pal system YbgF family protein -
  V5F96_RS04220 (V5F96_04230) purE 816936..817421 (+) 486 WP_003688684.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  V5F96_RS04225 (V5F96_04235) - 817633..818497 (-) 865 Protein_825 transposase -
  V5F96_RS04230 (V5F96_04240) - 818814..819179 (+) 366 Protein_826 transposase -
  V5F96_RS04235 (V5F96_04245) - 819201..820205 (+) 1005 Protein_827 autotransporter outer membrane beta-barrel domain-containing protein -
  V5F96_RS04240 (V5F96_04250) - 820406..821062 (-) 657 WP_003688682.1 response regulator transcription factor -
  V5F96_RS04245 (V5F96_04255) - 821059..822828 (-) 1770 WP_003691205.1 histidine kinase -
  V5F96_RS04250 (V5F96_04260) - 823035..823649 (+) 615 WP_003691204.1 molybdenum cofactor guanylyltransferase -
  V5F96_RS04255 (V5F96_04265) - 823812..824429 (+) 618 WP_010358100.1 riboflavin synthase -
  V5F96_RS04260 (V5F96_04270) - 824437..825300 (+) 864 WP_003688678.1 ATP-binding protein -
  V5F96_RS04265 (V5F96_04275) - 825313..825747 (-) 435 WP_003688677.1 Spy/CpxP family protein refolding chaperone -
  V5F96_RS04270 (V5F96_04280) rpe 825893..826576 (+) 684 WP_003688675.1 ribulose-phosphate 3-epimerase -
  V5F96_RS04275 (V5F96_04285) ruvB 826821..827852 (-) 1032 WP_003691202.1 Holliday junction branch migration DNA helicase RuvB -
  V5F96_RS04280 (V5F96_04290) - 827934..828242 (-) 309 WP_002232489.1 hypothetical protein -
  V5F96_RS04285 (V5F96_04295) - 828661..829893 (-) 1233 WP_003691200.1 multifunctional CCA addition/repair protein -
  V5F96_RS04290 (V5F96_04300) - 829972..831600 (-) 1629 WP_010951119.1 ABC-F family ATPase -
  V5F96_RS04295 (V5F96_04305) - 831750..832124 (+) 375 WP_003688664.1 arsenate reductase -
  V5F96_RS04300 (V5F96_04310) - 832173..833711 (+) 1539 WP_003691199.1 SurA N-terminal domain-containing protein -
  V5F96_RS04305 (V5F96_04315) recR 833778..834395 (+) 618 WP_003688660.1 recombination mediator RecR -
  V5F96_RS04310 (V5F96_04320) - 834451..834729 (-) 279 WP_003688659.1 hypothetical protein -
  V5F96_RS04315 (V5F96_04325) - 834955..836202 (+) 1248 WP_003691197.1 lipoprotein-releasing ABC transporter permease subunit -
  V5F96_RS04320 (V5F96_04330) lolD 836195..836890 (+) 696 WP_003688655.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  V5F96_RS04325 (V5F96_04335) recD 836957..838702 (+) 1746 WP_003691195.1 exodeoxyribonuclease V subunit alpha Machinery gene
  V5F96_RS04330 (V5F96_04340) - 838774..839420 (-) 647 Protein_846 methyltransferase -
  V5F96_RS04335 (V5F96_04345) - 839428..840390 (+) 963 WP_017147020.1 IS110 family transposase -
  V5F96_RS04340 (V5F96_04350) - 840523..840978 (-) 456 Protein_848 methyltransferase -
  V5F96_RS04345 (V5F96_04355) lon 841230..843692 (+) 2463 WP_003691187.1 endopeptidase La -
  V5F96_RS04350 (V5F96_04360) - 843874..844143 (+) 270 WP_003688640.1 HU family DNA-binding protein -
  V5F96_RS04355 (V5F96_04365) - 844319..844753 (-) 435 WP_003688638.1 hypothetical protein -
  V5F96_RS04360 (V5F96_04370) - 844746..846053 (-) 1308 WP_003695291.1 homoserine dehydrogenase -
  V5F96_RS04365 (V5F96_04375) - 846249..846620 (+) 372 WP_003688636.1 Mth938-like domain-containing protein -
  V5F96_RS04370 (V5F96_04380) - 846697..848619 (+) 1923 WP_003691184.1 ATP-binding cassette domain-containing protein -
  V5F96_RS04375 (V5F96_04385) - 848606..849001 (+) 396 WP_010358122.1 hypothetical protein -
  V5F96_RS04380 (V5F96_04390) - 849092..849604 (+) 513 WP_003688633.1 hypothetical protein -
  V5F96_RS04385 (V5F96_04395) - 850049..850744 (-) 696 WP_033910499.1 DUF4400 domain-containing protein -
  V5F96_RS04390 (V5F96_04400) traD 850734..852776 (-) 2043 WP_003693097.1 type IV conjugative transfer system coupling protein TraD -
  V5F96_RS04395 (V5F96_04405) mobH 852773..855325 (-) 2553 WP_047949925.1 MobH family relaxase -
  V5F96_RS04400 (V5F96_04410) - 855322..855741 (-) 420 WP_003693104.1 hypothetical protein -
  V5F96_RS04405 (V5F96_04415) - 856252..856713 (+) 462 WP_012503638.1 lytic transglycosylase domain-containing protein -
  V5F96_RS04410 (V5F96_04420) - 856683..857204 (+) 522 WP_003695285.1 OmpA family protein -
  V5F96_RS04415 (V5F96_04425) traA 857260..857556 (+) 297 WP_003697092.1 TraA family conjugative transfer protein -
  V5F96_RS04420 (V5F96_04430) traL 857578..857859 (+) 282 WP_003693110.1 type IV conjugative transfer system protein TraL -
  V5F96_RS04425 (V5F96_04435) - 857856..858521 (+) 666 WP_003704028.1 conjugal transfer protein TraE -
  V5F96_RS04430 (V5F96_04440) - 858523..859257 (+) 735 WP_003695279.1 type-F conjugative transfer system secretin TraK -
  V5F96_RS04435 (V5F96_04445) - 859259..860572 (+) 1314 WP_003693116.1 TrbI/VirB10 family protein -
  V5F96_RS04440 (V5F96_04450) - 860582..861301 (+) 720 WP_003693119.1 DsbC family protein -
  V5F96_RS04445 (V5F96_04455) - 861298..861879 (+) 582 WP_017146802.1 TraV family lipoprotein -
  V5F96_RS04450 (V5F96_04460) traC 861889..864465 (+) 2577 WP_003693122.1 type IV secretion system protein TraC -
  V5F96_RS04455 (V5F96_04465) - 864493..865041 (+) 549 WP_003693124.1 hypothetical protein -
  V5F96_RS04460 (V5F96_04470) - 865041..865586 (+) 546 WP_003704029.1 S26 family signal peptidase -
  V5F96_RS04465 (V5F96_04475) - 865595..866251 (+) 657 WP_003695268.1 hypothetical protein -
  V5F96_RS04470 (V5F96_04480) - 866248..867366 (+) 1119 WP_003695266.1 TraU family protein -
  V5F96_RS04475 (V5F96_04485) trbC 867381..868133 (+) 753 WP_003699946.1 type-F conjugative transfer system pilin assembly protein TrbC -
  V5F96_RS04480 (V5F96_04490) - 868130..869374 (+) 1245 WP_033909962.1 hypothetical protein -
  V5F96_RS04485 (V5F96_04495) traN 869413..870954 (+) 1542 WP_226876101.1 conjugal transfer protein TraN -
  V5F96_RS04490 (V5F96_04500) - 870941..871366 (+) 426 WP_003693140.1 hypothetical protein -
  V5F96_RS04495 (V5F96_04505) - 871378..872154 (+) 777 WP_012503632.1 thioredoxin family protein -
  V5F96_RS04500 (V5F96_04510) - 872326..873837 (+) 1512 WP_003693144.1 conjugal transfer protein TraH -
  V5F96_RS04505 (V5F96_04515) - 873844..876756 (+) 2913 WP_047949926.1 conjugal transfer protein TraG N-terminal domain-containing protein -
  V5F96_RS04510 (V5F96_04520) - 876819..877262 (+) 444 WP_002255587.1 M23 family metallopeptidase -

Sequence


Protein


Download         Length: 348 a.a.        Molecular weight: 37642.87 Da        Isoelectric Point: 4.8330

>NTDB_id=936658 V5F96_RS04185 WP_003688695.1 808858..809904(+) (recA) [Neisseria gonorrhoeae strain WHO_W_2024]
MSDDKSKALAAALAQIEKSFGKGAIMKMDGSQQEENLEVISTGSLGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAV
AQCQKNGGVCAFVDAEHAFDPVYARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMG
DSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFYSSVRLDIRRTGSIKKGEEVLGN
ETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELIDIGVKNDIINKSGAWYSYNGAKIGQGKDNVRVWLKENPEISDEID
AKIRALNGVEMHITEGTQDETDGERPEE

Nucleotide


Download         Length: 1047 bp        

>NTDB_id=936658 V5F96_RS04185 WP_003688695.1 808858..809904(+) (recA) [Neisseria gonorrhoeae strain WHO_W_2024]
ATGTCAGACGACAAAAGCAAAGCCCTTGCCGCCGCACTGGCGCAAATCGAAAAAAGTTTCGGCAAAGGCGCCATCATGAA
AATGGACGGCAGCCAGCAGGAAGAAAACCTCGAAGTCATTTCCACCGGATCGCTCGGATTAGACCTCGCCCTCGGAGTCG
GCGGCCTGCCGCGCGGGCGCATCGTCGAAATCTTCGGCCCCGAATCCTCCGGCAAAACCACACTCTGCCTCGAAGCCGTC
GCCCAATGCCAGAAAAACGGCGGCGTGTGCGCCTTTGTCGATGCCGAACACGCCTTCGATCCCGTTTACGCCCGCAAACT
CGGCGTAAAAGTCGAAGAGCTTTACCTGTCCCAGCCCGATACCGGCGAACAGGCTTTGGAAATCTGCGACACGCTCGTCC
GTTCGGGCGGCATAGATATGGTAGTCGTCGATTCCGTAGCCGCACTCGTCCCCAAAGCCGAAATCGAAGGCGATATGGGG
GACAGCCACGTCGGACTGCAGGCGCGCCTGATGAGTCAGGCTTTGCGCAAACTGACCGGACACATCAAAAAAACCAATAC
GCTGGTTGTGTTCATCAACCAAATCCGAATGAAGATCGGCGTAATGTTCGGCAGCCCCGAGACCACGACCGGCGGCAACG
CGCTGAAATTCTATTCTTCCGTCCGCCTCGACATCCGCCGCACCGGATCCATCAAAAAAGGCGAAGAAGTATTGGGCAAC
GAAACCCGCGTCAAAGTCATCAAAAACAAAGTCGCCCCCCCGTTCCGTCAGGCAGAGTTTGACATCCTCTACGGAGAAGG
CATCAGTTGGGAAGGCGAATTGATCGACATCGGCGTGAAAAACGACATCATCAACAAATCCGGCGCGTGGTACAGCTACA
ACGGCGCGAAAATCGGTCAGGGCAAAGACAACGTCCGCGTCTGGCTGAAAGAAAACCCCGAAATTTCCGACGAAATCGAC
GCAAAAATCCGCGCCCTCAACGGCGTAGAAATGCACATCACCGAAGGGACGCAGGACGAAACCGACGGCGAACGACCCGA
AGAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5F8M9

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recA Neisseria gonorrhoeae MS11

100

100

1

  recA Neisseria gonorrhoeae strain FA1090

100

100

1

  recA Neisseria gonorrhoeae MS11

100

100

1

  recA Ralstonia pseudosolanacearum GMI1000

74.468

94.54

0.704

  recA Vibrio cholerae O1 biovar El Tor strain E7946

66.949

100

0.681

  recA Vibrio cholerae strain A1552

66.949

100

0.681

  recA Glaesserella parasuis strain SC1401

67.521

100

0.681

  recA Pseudomonas stutzeri DSM 10701

71.692

93.391

0.67

  recA Acinetobacter baylyi ADP1

66.859

99.713

0.667

  recA Acinetobacter baumannii D1279779

65.517

100

0.655

  recA Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

65.103

97.989

0.638

  recA Riemerella anatipestifer ATCC 11845 = DSM 15868

67.073

94.253

0.632

  recA Helicobacter pylori 26695

67.077

93.391

0.626

  recA Helicobacter pylori strain NCTC11637

66.769

93.391

0.624

  recA Bacillus subtilis subsp. subtilis str. 168

65.138

93.966

0.612

  recA Streptococcus mutans UA159

60.684

100

0.612

  recA Streptococcus pneumoniae TIGR4

59.544

100

0.601

  recA Streptococcus pneumoniae Rx1

59.544

100

0.601

  recA Streptococcus pneumoniae D39

59.544

100

0.601

  recA Streptococcus pneumoniae R6

59.544

100

0.601

  recA Streptococcus mitis NCTC 12261

59.884

98.851

0.592

  recA Latilactobacillus sakei subsp. sakei 23K

62.691

93.966

0.589

  recA Streptococcus pyogenes NZ131

61.963

93.678

0.58

  recA Streptococcus mitis SK321

60.606

94.828

0.575

  recA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

60.121

95.115

0.572

  recA Lactococcus lactis subsp. cremoris KW2

60.303

94.828

0.572