Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   V5F99_RS01395 Genome accession   NZ_CP145053
Coordinates   278207..280426 (+) Length   739 a.a.
NCBI ID   WP_154235978.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_beta_2024     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 273207..285426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V5F99_RS01385 (V5F99_01395) - 273223..277821 (-) 4599 WP_104691705.1 S6 family peptidase -
  V5F99_RS01390 (V5F99_01400) - 277900..278175 (-) 276 WP_153707850.1 hypothetical protein -
  V5F99_RS01395 (V5F99_01405) comA 278207..280426 (+) 2220 WP_154235978.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  V5F99_RS01400 (V5F99_01410) comL 280496..281299 (-) 804 WP_003687645.1 outer membrane protein assembly factor BamD Machinery gene
  V5F99_RS01405 (V5F99_01415) rluD 281298..282422 (+) 1125 WP_003687642.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  V5F99_RS01410 (V5F99_01420) - 282575..283522 (-) 948 Protein_276 bile acid:sodium symporter family protein -
  V5F99_RS01415 (V5F99_01425) - 283599..283823 (-) 225 WP_225577482.1 hypothetical protein -
  V5F99_RS01420 (V5F99_01430) pgeF 283975..284754 (+) 780 WP_003687651.1 peptidoglycan editing factor PgeF -
  V5F99_RS01425 (V5F99_01435) lptE 284806..285285 (+) 480 WP_003687653.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79961.82 Da        Isoelectric Point: 10.3520

>NTDB_id=936545 V5F99_RS01395 WP_154235978.1 278207..280426(+) (comA) [Neisseria gonorrhoeae strain WHO_beta_2024]
MFRRWFLPCWVVGVAVSFALSVVPHWPFWLAAFAVLAVLARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGV
GTVGADRVLLHGGSGWGIAVWRSRISRNWRQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVLFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPLAVLGVGTWLSFGLVAALIWACAGRLYEGKRQTAVRGQWAASVLSLVLLGYLFASLPLVSPLVNAVSIPWFSW
VLTPLALLGSVVPFAPLQQAGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVSYRPEAVPENEAAVTVWDAGQGLSVLVRTANRHLLFDTGTVAAAQTGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLRPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEAELVK
KYGSNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRVYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=936545 V5F99_RS01395 WP_154235978.1 278207..280426(+) (comA) [Neisseria gonorrhoeae strain WHO_beta_2024]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGTGGCAGTTTCGTTCGCACTGTCGGTTGTACCGCATTGGCC
GTTTTGGTTGGCGGCTTTTGCGGTTTTGGCTGTGCTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCTGCAAAGGCTGTGGACAGCGGCGG
TCGGACGTTCGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGCG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGATAGGCGGCGTG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
CAATTGGCGGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGACTGACGCATTTGGTCAGTATCTCGGGTTTGCACGTT
ACGATGGTGGCGGTGCTGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCCGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCGGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTCGCGTGGGCGTGGCGCAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCTTTGGCGGTTTTGGGTGTCGGTACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTGCAGGGCGTTTGTACGAGGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCTCTGG
TTTTGCTCGGTTATCTGTTTGCCTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGTCGATACCGTGGTTTTCTTGG
GTGTTGACCCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGGGGCATTTTTGGCGGAATA
CACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCTGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTATCCTACCGTCCTGAAGCAGTACCTGAAAACGAAGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGCTTGTCGGT
GCTTGTGCGGACGGCAAACCGCCATCTGCTTTTCGATACGGGAACGGTAGCGGCGGCACAAACGGGTATCGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGCTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTCGAGTTTTTGAGGCCGTCTGAACGCAAAAATATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGAGATTTGGATACGAAAGGTGAGGCGGAGTTGGTTAAA
AAATACGGCTCAAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTTTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAGCATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAGTTGTTGCGGACGGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGACGCGGAGGC
GTAAAGGCTCAACGTTTGAGAGTGTATAAATTCTATTGGCAGAAAAAACCGTTTGAGTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(208-465)

Domain of unknown function (DUF4131) (DUF4131)

(7-167)

Metallo-beta-lactamase superfamily (Lactamase_B)

(500-677)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

99.053

100

0.991